Mitchell JC - Search Results

1

Mechanisms of TDP-43 Proteinopathy Onset and Propagation.

Chen HJ, Mitchell JC. Chen HJ, et al. Among authors: mitchell jc. Int J Mol Sci. 2021 Jun 2;22(11):6004. doi: 10.3390/ijms22116004. Int J Mol Sci. 2021. PMID: 34199367 Free PMC article. Review.

2

ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules.

Vance C, Scotter EL, Nishimura AL, Troakes C, Mitchell JC, Kathe C, Urwin H, Manser C, Miller CC, Hortobágyi T, Dragunow M, Rogelj B, Shaw CE. Vance C, et al. Among authors: mitchell jc. Hum Mol Genet. 2013 Jul 1;22(13):2676-88. doi: 10.1093/hmg/ddt117. Epub 2013 Mar 7. Hum Mol Genet. 2013. PMID: 23474818 Free PMC article.

3

Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species.

Scotter EL, Vance C, Nishimura AL, Lee YB, Chen HJ, Urwin H, Sardone V, Mitchell JC, Rogelj B, Rubinsztein DC, Shaw CE. Scotter EL, et al. Among authors: mitchell jc. J Cell Sci. 2014 Mar 15;127(Pt 6):1263-78. doi: 10.1242/jcs.140087. Epub 2014 Jan 14. J Cell Sci. 2014. PMID: 24424030 Free PMC article.

4

ER-mitochondria associations are regulated by the VAPB-PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43.

Stoica R, De Vos KJ, Paillusson S, Mueller S, Sancho RM, Lau KF, Vizcay-Barrena G, Lin WL, Xu YF, Lewis J, Dickson DW, Petrucelli L, Mitchell JC, Shaw CE, Miller CC. Stoica R, et al. Among authors: mitchell jc. Nat Commun. 2014 Jun 3;5:3996. doi: 10.1038/ncomms4996. Nat Commun. 2014. PMID: 24893131 Free PMC article.

5

The heat shock response plays an important role in TDP-43 clearance: evidence for dysfunction in amyotrophic lateral sclerosis.

Chen HJ, Mitchell JC, Novoselov S, Miller J, Nishimura AL, Scotter EL, Vance CA, Cheetham ME, Shaw CE. Chen HJ, et al. Among authors: mitchell jc. Brain. 2016 May;139(Pt 5):1417-32. doi: 10.1093/brain/aww028. Epub 2016 Mar 1. Brain. 2016. PMID: 26936937 Free PMC article.

6

Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis.

Smith BN, Topp SD, Fallini C, Shibata H, Chen HJ, Troakes C, King A, Ticozzi N, Kenna KP, Soragia-Gkazi A, Miller JW, Sato A, Dias DM, Jeon M, Vance C, Wong CH, de Majo M, Kattuah W, Mitchell JC, Scotter EL, Parkin NW, Sapp PC, Nolan M, Nestor PJ, Simpson M, Weale M, Lek M, Baas F, Vianney de Jong JM, Ten Asbroek ALMA, Redondo AG, Esteban-Pérez J, Tiloca C, Verde F, Duga S, Leigh N, Pall H, Morrison KE, Al-Chalabi A, Shaw PJ, Kirby J, Turner MR, Talbot K, Hardiman O, Glass JD, De Belleroche J, Maki M, Moss SE, Miller C, Gellera C, Ratti A, Al-Sarraj S, Brown RH Jr, Silani V, Landers JE, Shaw CE. Smith BN, et al. Among authors: mitchell jc. Sci Transl Med. 2017 May 3;9(388):eaad9157. doi: 10.1126/scitranslmed.aad9157. Sci Transl Med. 2017. PMID: 28469040 Free PMC article.

7

Mitochondrial abnormalities and disruption of the neuromuscular junction precede the clinical phenotype and motor neuron loss in hFUSWT transgenic mice.

So E, Mitchell JC, Memmi C, Chennell G, Vizcay-Barrena G, Allison L, Shaw CE, Vance C. So E, et al. Among authors: mitchell jc. Hum Mol Genet. 2018 Feb 1;27(3):463-474. doi: 10.1093/hmg/ddx415. Hum Mol Genet. 2018. PMID: 29194538 Free PMC article.

8

Review: Modelling the pathology and behaviour of frontotemporal dementia.

Solomon DA, Mitchell JC, Salcher-Konrad MT, Vance CA, Mizielinska S. Solomon DA, et al. Among authors: mitchell jc. Neuropathol Appl Neurobiol. 2019 Feb;45(1):58-80. doi: 10.1111/nan.12536. Neuropathol Appl Neurobiol. 2019. PMID: 30582188 Review.

9

Cytoplasmic TDP-43 is involved in cell fate during stress recovery.

Lee YB, Scotter EL, Lee DY, Troakes C, Mitchell J, Rogelj B, Gallo JM, Shaw CE. Lee YB, et al. Hum Mol Genet. 2021 Dec 27;31(2):166-175. doi: 10.1093/hmg/ddab227. Hum Mol Genet. 2021. PMID: 34378050 Free PMC article.

10

Amyotrophic lateral sclerosis mutant vesicle-associated membrane protein-associated protein-B transgenic mice develop TAR-DNA-binding protein-43 pathology.

Tudor EL, Galtrey CM, Perkinton MS, Lau KF, De Vos KJ, Mitchell JC, Ackerley S, Hortobágyi T, Vámos E, Leigh PN, Klasen C, McLoughlin DM, Shaw CE, Miller CC. Tudor EL, et al. Among authors: mitchell jc. Neuroscience. 2010 May 19;167(3):774-85. doi: 10.1016/j.neuroscience.2010.02.035. Epub 2010 Feb 24. Neuroscience. 2010. PMID: 20188146

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