Schaid MD - Search Results

1

Prostaglandin EP3 receptor signaling is required to prevent insulin hypersecretion and metabolic dysfunction in a non-obese mouse model of insulin resistance.

Wisinski JA, Reuter A, Peter DC, Schaid MD, Fenske RJ, Kimple ME. Wisinski JA, et al. Among authors: schaid md. Am J Physiol Endocrinol Metab. 2021 Oct 1;321(4):E479-E489. doi: 10.1152/ajpendo.00051.2021. Epub 2021 Jul 6. Am J Physiol Endocrinol Metab. 2021. PMID: 34229444 Free PMC article.

2

Synergy Between Gαz Deficiency and GLP-1 Analog Treatment in Preserving Functional β-Cell Mass in Experimental Diabetes.

Brill AL, Wisinski JA, Cadena MT, Thompson MF, Fenske RJ, Brar HK, Schaid MD, Pasker RL, Kimple ME. Brill AL, et al. Among authors: schaid md. Mol Endocrinol. 2016 May;30(5):543-56. doi: 10.1210/me.2015-1164. Epub 2016 Apr 6. Mol Endocrinol. 2016. PMID: 27049466 Free PMC article.

3

Enriching Islet Phospholipids With Eicosapentaenoic Acid Reduces Prostaglandin E₂ Signaling and Enhances Diabetic β-Cell Function.

Neuman JC, Schaid MD, Brill AL, Fenske RJ, Kibbe CR, Fontaine DA, Sdao SM, Brar HK, Connors KM, Wienkes HN, Eliceiri KW, Merrins MJ, Davis DB, Kimple ME. Neuman JC, et al. Among authors: schaid md. Diabetes. 2017 Jun;66(6):1572-1585. doi: 10.2337/db16-1362. Epub 2017 Feb 13. Diabetes. 2017. PMID: 28193789 Free PMC article.

4

The Inhibitory G Protein α-Subunit, Gαz, Promotes Type 1 Diabetes-Like Pathophysiology in NOD Mice.

Fenske RJ, Cadena MT, Harenda QE, Wienkes HN, Carbajal K, Schaid MD, Laundre E, Brill AL, Truchan NA, Brar H, Wisinski J, Cai J, Graham TE, Engin F, Kimple ME. Fenske RJ, et al. Among authors: schaid md. Endocrinology. 2017 Jun 1;158(6):1645-1658. doi: 10.1210/en.2016-1700. Endocrinology. 2017. PMID: 28419211 Free PMC article.

5

The EP3 Receptor/G_z Signaling Axis as a Therapeutic Target for Diabetes and Cardiovascular Disease.

Schaid MD, Wisinski JA, Kimple ME. Schaid MD, et al. AAPS J. 2017 Sep;19(5):1276-1283. doi: 10.1208/s12248-017-0097-1. Epub 2017 Jun 5. AAPS J. 2017. PMID: 28584908 Free PMC article. Review.

6

Restoration of metabolic health by decreased consumption of branched-chain amino acids.

Cummings NE, Williams EM, Kasza I, Konon EN, Schaid MD, Schmidt BA, Poudel C, Sherman DS, Yu D, Arriola Apelo SI, Cottrell SE, Geiger G, Barnes ME, Wisinski JA, Fenske RJ, Matkowskyj KA, Kimple ME, Alexander CM, Merrins MJ, Lamming DW. Cummings NE, et al. Among authors: schaid md. J Physiol. 2018 Feb 15;596(4):623-645. doi: 10.1113/JP275075. Epub 2017 Dec 27. J Physiol. 2018. PMID: 29266268 Free PMC article.

7

Complement 1q-like-3 protein inhibits insulin secretion from pancreatic β-cells via the cell adhesion G protein-coupled receptor BAI3.

Gupta R, Nguyen DC, Schaid MD, Lei X, Balamurugan AN, Wong GW, Kim JA, Koltes JE, Kimple ME, Bhatnagar S. Gupta R, et al. Among authors: schaid md. J Biol Chem. 2018 Nov 23;293(47):18086-18098. doi: 10.1074/jbc.RA118.005403. Epub 2018 Sep 18. J Biol Chem. 2018. PMID: 30228187 Free PMC article.

8

A gene expression network analysis of the pancreatic islets from lean and obese mice identifies complement 1q like-3 secreted protein as a regulator of β-cell function.

Koltes JE, Arora I, Gupta R, Nguyen DC, Schaid M, Kim JA, Kimple ME, Bhatnagar S. Koltes JE, et al. Sci Rep. 2019 Jul 12;9(1):10119. doi: 10.1038/s41598-019-46219-3. Sci Rep. 2019. PMID: 31300714 Free PMC article.

9

Ultrahigh-Resolution Mass Spectrometry-Based Platform for Plasma Metabolomics Applied to Type 2 Diabetes Research.

Zhu Y, Wancewicz B, Schaid M, Tiambeng TN, Wenger K, Jin Y, Heyman H, Thompson CJ, Barsch A, Cox ED, Davis DB, Brasier AR, Kimple ME, Ge Y. Zhu Y, et al. J Proteome Res. 2021 Jan 1;20(1):463-473. doi: 10.1021/acs.jproteome.0c00510. Epub 2020 Oct 15. J Proteome Res. 2021. PMID: 33054244 Free PMC article.

10

Agonist-independent Gα_z activity negatively regulates beta-cell compensation in a diet-induced obesity model of type 2 diabetes.

Schaid MD, Green CL, Peter DC, Gallagher SJ, Guthery E, Carbajal KA, Harrington JM, Kelly GM, Reuter A, Wehner ML, Brill AL, Neuman JC, Lamming DW, Kimple ME. Schaid MD, et al. J Biol Chem. 2021 Jan-Jun;296:100056. doi: 10.1074/jbc.RA120.015585. Epub 2020 Nov 24. J Biol Chem. 2021. PMID: 33172888 Free PMC article.

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