Buhl DL - Search Results

1

Safety, pharmacokinetics and quantitative EEG modulation of TAK-071, a novel muscarinic M1 receptor positive allosteric modulator, in healthy subjects.

Yin W, Mamashli F, Buhl DL, Khudyakov P, Volfson D, Martenyi F, Gevorkyan H, Rosen L, Simen AA. Yin W, et al. Among authors: buhl dl. Br J Clin Pharmacol. 2022 Feb;88(2):600-612. doi: 10.1111/bcp.14975. Epub 2021 Jul 31. Br J Clin Pharmacol. 2022. PMID: 34240455 Free PMC article. Clinical Trial.

2

Pharmacological evaluation of clinically relevant concentrations of (2R,6R)-hydroxynorketamine.

Shaffer CL, Dutra JK, Tseng WC, Weber ML, Bogart LJ, Hales K, Pang J, Volfson D, Am Ende CW, Green ME, Buhl DL. Shaffer CL, et al. Among authors: buhl dl. Neuropharmacology. 2019 Jul 15;153:73-81. doi: 10.1016/j.neuropharm.2019.04.019. Epub 2019 Apr 20. Neuropharmacology. 2019. PMID: 31015046

3

Transcranial magnetic stimulation as a translational biomarker for AMPA receptor modulation.

O'Donnell P, Dijkstra FM, Damar U, Quanhong L, de Goede AA, Xu L, Pascual-Leone A, Buhl DL, Zuiker R, Ruijs TQ, Heuberger JAAC, MacMullin P, Lubell M, Asgharnejad M, Murthy V, Rotenberg A, Jacobs GE, Rosen L. O'Donnell P, et al. Among authors: buhl dl. Transl Psychiatry. 2021 May 27;11(1):325. doi: 10.1038/s41398-021-01451-2. Transl Psychiatry. 2021. PMID: 34045439 Free PMC article. Clinical Trial.

4

Central nervous system effects of TAK-653, an investigational alpha-amino-3-hydroxy-5-methyl-4-isoxazole receptor (AMPAR) positive allosteric modulator in healthy volunteers.

Dijkstra F, O'Donnell P, Klaassen E, Buhl D, Asgharnejad M, Rosen L, Zuiker R, van Gerven J, Jacobs G. Dijkstra F, et al. Transl Psychiatry. 2022 Sep 24;12(1):408. doi: 10.1038/s41398-022-02148-w. Transl Psychiatry. 2022. PMID: 36153330 Free PMC article. Clinical Trial.

5

Identifying time-resolved features of nocturnal sleep characteristics of narcolepsy using machine learning.

Vilela M, Tracey B, Volfson D, Barateau L, Cai A, Buhl DL, Dauvilliers Y. Vilela M, et al. Among authors: buhl dl. J Sleep Res. 2024 Dec;33(6):e14216. doi: 10.1111/jsr.14216. Epub 2024 Apr 26. J Sleep Res. 2024. PMID: 38665127 Free PMC article.

6

Pronounced antiepileptic activity of the subtype-selective GABA_A -positive allosteric modulator PF-06372865 in the GAERS absence epilepsy model.

Duveau V, Buhl DL, Evrard A, Ruggiero C, Mandé-Niedergang B, Roucard C, Gurrell R. Duveau V, et al. Among authors: buhl dl. CNS Neurosci Ther. 2019 Feb;25(2):255-260. doi: 10.1111/cns.13046. Epub 2018 Aug 12. CNS Neurosci Ther. 2019. PMID: 30101518 Free PMC article.

7

A Novel Binding Mode Reveals Two Distinct Classes of NMDA Receptor GluN2B-selective Antagonists.

Stroebel D, Buhl DL, Knafels JD, Chanda PK, Green M, Sciabola S, Mony L, Paoletti P, Pandit J. Stroebel D, et al. Among authors: buhl dl. Mol Pharmacol. 2016 May;89(5):541-51. doi: 10.1124/mol.115.103036. Epub 2016 Feb 24. Mol Pharmacol. 2016. PMID: 26912815 Free PMC article.

8

Peripheral Administration of a Long-Acting Peptide Oxytocin Receptor Agonist Inhibits Fear-Induced Freezing.

Modi ME, Majchrzak MJ, Fonseca KR, Doran A, Osgood S, Vanase-Frawley M, Feyfant E, McInnes H, Darvari R, Buhl DL, Kablaoui NM. Modi ME, et al. Among authors: buhl dl. J Pharmacol Exp Ther. 2016 Aug;358(2):164-72. doi: 10.1124/jpet.116.232702. Epub 2016 May 23. J Pharmacol Exp Ther. 2016. PMID: 27217590 Free PMC article.

9

GluN2D-mediated excitatory drive onto medial prefrontal cortical PV+ fast-spiking inhibitory interneurons.

Garst-Orozco J, Malik R, Lanz TA, Weber ML, Xi H, Arion D, Enwright JF 3rd, Lewis DA, O'Donnell P, Sohal VS, Buhl DL. Garst-Orozco J, et al. Among authors: buhl dl. PLoS One. 2020 Jun 4;15(6):e0233895. doi: 10.1371/journal.pone.0233895. eCollection 2020. PLoS One. 2020. PMID: 32497062 Free PMC article.

10

Schizophrenia-associated SLC39A8 polymorphism is a loss-of-function allele altering glutamate receptor and innate immune signaling.

Tseng WC, Reinhart V, Lanz TA, Weber ML, Pang J, Le KXV, Bell RD, O'Donnell P, Buhl DL. Tseng WC, et al. Among authors: buhl dl. Transl Psychiatry. 2021 Feb 19;11(1):136. doi: 10.1038/s41398-021-01262-5. Transl Psychiatry. 2021. PMID: 33608496 Free PMC article.

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