Ghosh P - Search Results

1

Artificial intelligence guided discovery of a barrier-protective therapy in inflammatory bowel disease.

Sahoo D, Swanson L, Sayed IM, Katkar GD, Ibeawuchi SR, Mittal Y, Pranadinata RF, Tindle C, Fuller M, Stec DL, Chang JT, Sandborn WJ, Das S, Ghosh P. Sahoo D, et al. Among authors: ghosh p. Nat Commun. 2021 Jul 12;12(1):4246. doi: 10.1038/s41467-021-24470-5. Nat Commun. 2021. PMID: 34253728 Free PMC article.

2

Src homology domain 2-containing protein-tyrosine phosphatase-1 (SHP-1) binds and dephosphorylates G(alpha)-interacting, vesicle-associated protein (GIV)/Girdin and attenuates the GIV-phosphatidylinositol 3-kinase (PI3K)-Akt signaling pathway.

Mittal Y, Pavlova Y, Garcia-Marcos M, Ghosh P. Mittal Y, et al. Among authors: ghosh p. J Biol Chem. 2011 Sep 16;286(37):32404-15. doi: 10.1074/jbc.M111.275685. Epub 2011 Jul 28. J Biol Chem. 2011. PMID: 21799016 Free PMC article.

3

Tyrosine phosphorylation of the Gα-interacting protein GIV promotes activation of phosphoinositide 3-kinase during cell migration.

Lin C, Ear J, Pavlova Y, Mittal Y, Kufareva I, Ghassemian M, Abagyan R, Garcia-Marcos M, Ghosh P. Lin C, et al. Among authors: ghosh p. Sci Signal. 2011 Sep 27;4(192):ra64. doi: 10.1126/scisignal.2002049. Sci Signal. 2011. PMID: 21954290 Free PMC article.

4

STAT3 protein up-regulates Gα-interacting vesicle-associated protein (GIV)/Girdin expression, and GIV enhances STAT3 activation in a positive feedback loop during wound healing and tumor invasion/metastasis.

Dunkel Y, Ong A, Notani D, Mittal Y, Lam M, Mi X, Ghosh P. Dunkel Y, et al. Among authors: ghosh p. J Biol Chem. 2012 Dec 7;287(50):41667-83. doi: 10.1074/jbc.M112.390781. Epub 2012 Oct 12. J Biol Chem. 2012. PMID: 23066027 Free PMC article.

5

Protein kinase C-theta (PKCθ) phosphorylates and inhibits the guanine exchange factor, GIV/Girdin.

López-Sánchez I, Garcia-Marcos M, Mittal Y, Aznar N, Farquhar MG, Ghosh P. López-Sánchez I, et al. Among authors: ghosh p. Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5510-5. doi: 10.1073/pnas.1303392110. Epub 2013 Mar 18. Proc Natl Acad Sci U S A. 2013. PMID: 23509302 Free PMC article.

6

GIV/Girdin is a central hub for profibrogenic signalling networks during liver fibrosis.

Lopez-Sanchez I, Dunkel Y, Roh YS, Mittal Y, De Minicis S, Muranyi A, Singh S, Shanmugam K, Aroonsakool N, Murray F, Ho SB, Seki E, Brenner DA, Ghosh P. Lopez-Sanchez I, et al. Among authors: ghosh p. Nat Commun. 2014 Jul 21;5:4451. doi: 10.1038/ncomms5451. Nat Commun. 2014. PMID: 25043713 Free PMC article.

7

Glycan Sulfation Modulates Dendritic Cell Biology and Tumor Growth.

El Ghazal R, Yin X, Johns SC, Swanson L, Macal M, Ghosh P, Zuniga EI, Fuster MM. El Ghazal R, et al. Among authors: ghosh p. Neoplasia. 2016 May;18(5):294-306. doi: 10.1016/j.neo.2016.04.004. Neoplasia. 2016. PMID: 27237321 Free PMC article.

8

Prognostic impact of total and tyrosine phosphorylated GIV/Girdin in breast cancers.

Dunkel Y, Diao K, Aznar N, Swanson L, Liu L, Zhu W, Mi XY, Ghosh P. Dunkel Y, et al. Among authors: ghosh p. FASEB J. 2016 Nov;30(11):3702-3713. doi: 10.1096/fj.201600500. Epub 2016 Jul 20. FASEB J. 2016. PMID: 27440794 Free PMC article.

A Kaplan-Meier analysis of recurrence-free survival showed that the presence of tGIV, either cytoplasmic or nuclear, carried poor prognosis, but that nuclear tGIV had a greater prognostic impact (P = 0.007 in early and P = 0.0048 in late clinical stages). Activated …

A Kaplan-Meier analysis of recurrence-free survival showed that the presence of tGIV, either cytoplasmic or nuclear, carried poor prognosis, …

9

Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses.

Dallari S, Macal M, Loureiro ME, Jo Y, Swanson L, Hesser C, Ghosh P, Zuniga EI. Dallari S, et al. Among authors: ghosh p. Nat Commun. 2017 Apr 3;8:14830. doi: 10.1038/ncomms14830. Nat Commun. 2017. PMID: 28368000 Free PMC article.

10

Convergence of Wnt, growth factor, and heterotrimeric G protein signals on the guanine nucleotide exchange factor Daple.

Aznar N, Ear J, Dunkel Y, Sun N, Satterfield K, He F, Kalogriopoulos NA, Lopez-Sanchez I, Ghassemian M, Sahoo D, Kufareva I, Ghosh P. Aznar N, et al. Among authors: ghosh p. Sci Signal. 2018 Feb 27;11(519):eaao4220. doi: 10.1126/scisignal.aao4220. Sci Signal. 2018. PMID: 29487190 Free PMC article.

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