Mi S - Search Results

1

Discovery of Potent Selective Nonzinc Binding Autotaxin Inhibitor BIO-32546.

Ma B, Zhang L, Sun L, Xin Z, Kumaravel G, Marcotte D, Chodaparambil JV, Wang Q, Wehr A, Jing J, Hong VS, Wang T, Huang C, Shao Z, Mi S. Ma B, et al. Among authors: mi s. ACS Med Chem Lett. 2021 Jun 14;12(7):1124-1129. doi: 10.1021/acsmedchemlett.1c00211. eCollection 2021 Jul 8. ACS Med Chem Lett. 2021. PMID: 34267882 Free PMC article.

2

Production of a PEGylated Fab' of the anti-LINGO-1 Li33 antibody and assessment of its biochemical and functional properties in vitro and in a rat model of remyelination.

Pepinsky RB, Walus L, Shao Z, Ji B, Gu S, Sun Y, Wen D, Lee X, Wang Q, Garber E, Mi S. Pepinsky RB, et al. Among authors: mi s. Bioconjug Chem. 2011 Feb 16;22(2):200-10. doi: 10.1021/bc1002746. Epub 2011 Jan 21. Bioconjug Chem. 2011. PMID: 21254764

3

Exposure levels of anti-LINGO-1 Li81 antibody in the central nervous system and dose-efficacy relationships in rat spinal cord remyelination models after systemic administration.

Pepinsky RB, Shao Z, Ji B, Wang Q, Meng G, Walus L, Lee X, Hu Y, Graff C, Garber E, Meier W, Mi S. Pepinsky RB, et al. Among authors: mi s. J Pharmacol Exp Ther. 2011 Nov;339(2):519-29. doi: 10.1124/jpet.111.183483. Epub 2011 Aug 1. J Pharmacol Exp Ther. 2011. PMID: 21807883

4

LINGO-1 Regulates Oligodendrocyte Differentiation through the Cytoplasmic Gelsolin Signaling Pathway.

Shao Z, Lee X, Huang G, Sheng G, Henderson CE, Louvard D, Sohn J, Pepinsky B, Mi S. Shao Z, et al. Among authors: mi s. J Neurosci. 2017 Mar 22;37(12):3127-3137. doi: 10.1523/JNEUROSCI.3722-16.2017. Epub 2017 Feb 13. J Neurosci. 2017. PMID: 28193690 Free PMC article.

5

Oligodendrocyte differentiation and myelination defects in OMgp null mice.

Lee X, Hu Y, Zhang Y, Yang Z, Shao Z, Qiu M, Pepinsky B, Miller RH, Mi S. Lee X, et al. Among authors: mi s. Mol Cell Neurosci. 2011 Apr;46(4):752-61. doi: 10.1016/j.mcn.2011.02.008. Epub 2011 Feb 23. Mol Cell Neurosci. 2011. PMID: 21352918

6

LINGO-1 regulates oligodendrocyte differentiation by inhibiting ErbB2 translocation and activation in lipid rafts.

Lee X, Shao Z, Sheng G, Pepinsky B, Mi S. Lee X, et al. Among authors: mi s. Mol Cell Neurosci. 2014 May;60:36-42. doi: 10.1016/j.mcn.2014.02.006. Epub 2014 Feb 28. Mol Cell Neurosci. 2014. PMID: 24583087

7

Functional activity of anti-LINGO-1 antibody opicinumab requires target engagement at a secondary binding site.

Hanf KJM, Arndt JW, Liu Y, Gong BJ, Rushe M, Sopko R, Massol R, Smith B, Gao Y, Dalkilic-Liddle I, Lee X, Mojta S, Shao Z, Mi S, Pepinsky RB. Hanf KJM, et al. Among authors: mi s. MAbs. 2020 Jan-Dec;12(1):1713648. doi: 10.1080/19420862.2020.1713648. MAbs. 2020. PMID: 31928294 Free PMC article.

8

A DR6/p75(NTR) complex is responsible for β-amyloid-induced cortical neuron death.

Hu Y, Lee X, Shao Z, Apicco D, Huang G, Gong BJ, Pepinsky RB, Mi S. Hu Y, et al. Among authors: mi s. Cell Death Dis. 2013 Apr 4;4(4):e579. doi: 10.1038/cddis.2013.110. Cell Death Dis. 2013. PMID: 23559013 Free PMC article.

9

Death receptor 6 (DR6) antagonist antibody is neuroprotective in the mouse SOD1G93A model of amyotrophic lateral sclerosis.

Huang G, Lee X, Bian Y, Shao Z, Sheng G, Pepinsky RB, Mi S. Huang G, et al. Among authors: mi s. Cell Death Dis. 2013 Oct 10;4(10):e841. doi: 10.1038/cddis.2013.378. Cell Death Dis. 2013. PMID: 24113175 Free PMC article.

10

LINGO-1 antagonist promotes functional recovery and axonal sprouting after spinal cord injury.

Ji B, Li M, Wu WT, Yick LW, Lee X, Shao Z, Wang J, So KF, McCoy JM, Pepinsky RB, Mi S, Relton JK. Ji B, et al. Among authors: mi s. Mol Cell Neurosci. 2006 Nov;33(3):311-20. doi: 10.1016/j.mcn.2006.08.003. Epub 2006 Sep 29. Mol Cell Neurosci. 2006. PMID: 17011208

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