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Interplay and cooperation between SREBF1 and master transcription factors regulate lipid metabolism and tumor-promoting pathways in squamous cancer.
Li LY, Yang Q, Jiang YY, Yang W, Jiang Y, Li X, Hazawa M, Zhou B, Huang GW, Xu XE, Gery S, Zhang Y, Ding LW, Ho AS, Zumsteg ZS, Wang MR, Fullwood MJ, Freedland SJ, Meltzer SJ, Xu LY, Li EM, Koeffler HP, Lin DC. Li LY, et al. Among authors: freedland sj. Nat Commun. 2021 Jul 16;12(1):4362. doi: 10.1038/s41467-021-24656-x. Nat Commun. 2021. PMID: 34272396 Free PMC article.
Number of Unfavorable Intermediate-Risk Factors Predicts Pathologic Upstaging and Prostate Cancer-Specific Mortality Following Radical Prostatectomy: Results From the SEARCH Database.
Zumsteg ZS, Chen Z, Howard LE, Amling CL, Aronson WJ, Cooperberg MR, Kane CJ, Terris MK, Spratt DE, Sandler HM, Freedland SJ. Zumsteg ZS, et al. Among authors: freedland sj. Prostate. 2017 Feb;77(2):154-163. doi: 10.1002/pros.23255. Epub 2016 Sep 29. Prostate. 2017. PMID: 27683213 Free article.
ONECUT2 is a targetable master regulator of lethal prostate cancer that suppresses the androgen axis.
Rotinen M, You S, Yang J, Coetzee SG, Reis-Sobreiro M, Huang WC, Huang F, Pan X, Yáñez A, Hazelett DJ, Chu CY, Steadman K, Morrissey CM, Nelson PS, Corey E, Chung LWK, Freedland SJ, Di Vizio D, Garraway IP, Murali R, Knudsen BS, Freeman MR. Rotinen M, et al. Among authors: freedland sj. Nat Med. 2018 Dec;24(12):1887-1898. doi: 10.1038/s41591-018-0241-1. Epub 2018 Nov 26. Nat Med. 2018. PMID: 30478421 Free PMC article.
High-fat diet fuels prostate cancer progression by rewiring the metabolome and amplifying the MYC program.
Labbé DP, Zadra G, Yang M, Reyes JM, Lin CY, Cacciatore S, Ebot EM, Creech AL, Giunchi F, Fiorentino M, Elfandy H, Syamala S, Karoly ED, Alshalalfa M, Erho N, Ross A, Schaeffer EM, Gibb EA, Takhar M, Den RB, Lehrer J, Karnes RJ, Freedland SJ, Davicioni E, Spratt DE, Ellis L, Jaffe JD, DʼAmico AV, Kantoff PW, Bradner JE, Mucci LA, Chavarro JE, Loda M, Brown M. Labbé DP, et al. Among authors: freedland sj. Nat Commun. 2019 Sep 25;10(1):4358. doi: 10.1038/s41467-019-12298-z. Nat Commun. 2019. PMID: 31554818 Free PMC article.
Plasma cells are enriched in localized prostate cancer in Black men and are associated with improved outcomes.
Weiner AB, Vidotto T, Liu Y, Mendes AA, Salles DC, Faisal FA, Murali S, McFarlane M, Imada EL, Zhao X, Li Z, Davicioni E, Marchionni L, Chinnaiyan AM, Freedland SJ, Spratt DE, Wu JD, Lotan TL, Schaeffer EM. Weiner AB, et al. Among authors: freedland sj. Nat Commun. 2021 Feb 10;12(1):935. doi: 10.1038/s41467-021-21245-w. Nat Commun. 2021. PMID: 33568675 Free PMC article.
Integrating PARP Inhibitors Into Advanced Prostate Cancer Therapeutics.
Gong J, Posadas E, Bhowmick N, Kim H, Daskivich T, Gupta A, Sandler H, Kamrava M, Zumsteg Z, Freedland S, Figlin R. Gong J, et al. Oncology (Williston Park). 2021 Mar 15;35(3):119-125. doi: 10.46883/ONC.2021.3503.0119. Oncology (Williston Park). 2021. PMID: 33818052 Review.
Lifestyle and sociodemographic factors associated with treatment choice of clinically localized prostate cancer in an equal access healthcare system.
Anderson EM, Gu L, Oyekunle T, De Hoedt AM, Wiggins E, Gay CJ, Lu DJ, Daskivich TJ, Freedland SJ, Zumsteg ZS, Csizmadi I. Anderson EM, et al. Among authors: freedland sj. Prostate Cancer Prostatic Dis. 2022 Sep;25(3):593-595. doi: 10.1038/s41391-022-00551-4. Epub 2022 May 26. Prostate Cancer Prostatic Dis. 2022. PMID: 35618798
773 results