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Interplay and cooperation between SREBF1 and master transcription factors regulate lipid metabolism and tumor-promoting pathways in squamous cancer.
Li LY, Yang Q, Jiang YY, Yang W, Jiang Y, Li X, Hazawa M, Zhou B, Huang GW, Xu XE, Gery S, Zhang Y, Ding LW, Ho AS, Zumsteg ZS, Wang MR, Fullwood MJ, Freedland SJ, Meltzer SJ, Xu LY, Li EM, Koeffler HP, Lin DC. Li LY, et al. Among authors: yang q, yang w. Nat Commun. 2021 Jul 16;12(1):4362. doi: 10.1038/s41467-021-24656-x. Nat Commun. 2021. PMID: 34272396 Free PMC article.
Master transcription factors form interconnected circuitry and orchestrate transcriptional networks in oesophageal adenocarcinoma.
Chen L, Huang M, Plummer J, Pan J, Jiang YY, Yang Q, Silva TC, Gull N, Chen S, Ding LW, An O, Yang H, Cheng Y, Said JW, Doan N, Dinjens WN, Waters KM, Tuli R, Gayther SA, Klempner SJ, Berman BP, Meltzer SJ, Lin DC, Koeffler HP. Chen L, et al. Among authors: yang q, yang h. Gut. 2020 Apr;69(4):630-640. doi: 10.1136/gutjnl-2019-318325. Epub 2019 Aug 13. Gut. 2020. PMID: 31409603 Free PMC article.
Lineage-Specific Epigenomic and Genomic Activation of Oncogene HNF4A Promotes Gastrointestinal Adenocarcinomas.
Pan J, Silva TC, Gull N, Yang Q, Plummer JT, Chen S, Daigo K, Hamakubo T, Gery S, Ding LW, Jiang YY, Hu S, Xu LY, Li EM, Ding Y, Klempner SJ, Gayther SA, Berman BP, Koeffler HP, Lin DC. Pan J, et al. Among authors: yang q. Cancer Res. 2020 Jul 1;80(13):2722-2736. doi: 10.1158/0008-5472.CAN-20-0390. Epub 2020 Apr 24. Cancer Res. 2020. PMID: 32332020
A Transcriptional Regulatory Loop of Master Regulator Transcription Factors, PPARG, and Fatty Acid Synthesis Promotes Esophageal Adenocarcinoma.
Ma S, Zhou B, Yang Q, Pan Y, Yang W, Freedland SJ, Ding LW, Freeman MR, Breunig JJ, Bhowmick NA, Pan J, Koeffler HP, Lin DC. Ma S, et al. Among authors: yang q, yang w. Cancer Res. 2021 Mar 1;81(5):1216-1229. doi: 10.1158/0008-5472.CAN-20-0652. Epub 2021 Jan 5. Cancer Res. 2021. PMID: 33402390 Free PMC article.
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