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The signal transducer CD24 suppresses the germ cell program and promotes an ectodermal rather than mesodermal cell fate in embryonal carcinomas.
Skowron MA, Becker TK, Kurz L, Jostes S, Bremmer F, Fronhoffs F, Funke K, Wakileh GA, Müller MR, Burmeister A, Lenz T, Stefanski A, Stühler K, Petzsch P, Köhrer K, Altevogt P, Albers P, Kristiansen G, Schorle H, Nettersheim D. Skowron MA, et al. Among authors: jostes s. Mol Oncol. 2022 Feb;16(4):982-1008. doi: 10.1002/1878-0261.13066. Epub 2021 Aug 2. Mol Oncol. 2022. PMID: 34293822 Free PMC article.
BMP Inhibition in Seminomas Initiates Acquisition of Pluripotency via NODAL Signaling Resulting in Reprogramming to an Embryonal Carcinoma.
Nettersheim D, Jostes S, Sharma R, Schneider S, Hofmann A, Ferreira HJ, Hoffmann P, Kristiansen G, Esteller MB, Schorle H. Nettersheim D, et al. Among authors: jostes s. PLoS Genet. 2015 Jul 30;11(7):e1005415. doi: 10.1371/journal.pgen.1005415. eCollection 2015 Jul. PLoS Genet. 2015. PMID: 26226633 Free PMC article.
18 results