An engineered human Fc domain that behaves like a pH-toggle switch for ultra-long circulation persistence.
Lee CH, Kang TH, Godon O, Watanabe M, Delidakis G, Gillis CM, Sterlin D, Hardy D, Cogné M, Macdonald LE, Murphy AJ, Tu N, Lee J, McDaniel JR, Makowski E, Tessier PM, Meyer AS, Bruhns P, Georgiou G.
Lee CH, et al. Among authors: tessier pm.
Nat Commun. 2019 Nov 6;10(1):5031. doi: 10.1038/s41467-019-13108-2.
Nat Commun. 2019.
PMID: 31695028
Free PMC article.