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MLK3 mediates impact of PKG1α on cardiac function and controls blood pressure through separate mechanisms.
Calamaras TD, Pande S, Baumgartner RA, Kim SK, McCarthy JC, Martin GL, Tam K, McLaughlin AL, Wang GR, Aronovitz MJ, Lin W, Aguirre JI, Baca P, Liu P, Richards DA, Davis RJ, Karas RH, Jaffe IZ, Blanton RM. Calamaras TD, et al. Among authors: jaffe iz. JCI Insight. 2021 Sep 22;6(18):e149075. doi: 10.1172/jci.insight.149075. JCI Insight. 2021. PMID: 34324442 Free PMC article.
Estrogen receptors alpha and beta mediate distinct pathways of vascular gene expression, including genes involved in mitochondrial electron transport and generation of reactive oxygen species.
O'Lone R, Knorr K, Jaffe IZ, Schaffer ME, Martini PG, Karas RH, Bienkowska J, Mendelsohn ME, Hansen U. O'Lone R, et al. Among authors: jaffe iz. Mol Endocrinol. 2007 Jun;21(6):1281-96. doi: 10.1210/me.2006-0497. Epub 2007 Mar 20. Mol Endocrinol. 2007. PMID: 17374850
Rapid recruitment of temporally distinct vascular gene sets by estrogen.
Schnoes KK, Jaffe IZ, Iyer L, Dabreo A, Aronovitz M, Newfell B, Hansen U, Rosano G, Mendelsohn ME. Schnoes KK, et al. Among authors: jaffe iz. Mol Endocrinol. 2008 Nov;22(11):2544-56. doi: 10.1210/me.2008-0044. Epub 2008 Sep 11. Mol Endocrinol. 2008. PMID: 18787042 Free PMC article.
Mineralocorticoid receptor antagonism inhibits vein graft remodeling in mice.
Ehsan A, McGraw AP, Aronovitz MJ, Galayda C, Conte MS, Karas RH, Jaffe IZ. Ehsan A, et al. Among authors: jaffe iz. J Thorac Cardiovasc Surg. 2013 Jun;145(6):1642-9, 1649.e1. doi: 10.1016/j.jtcvs.2012.08.007. Epub 2012 Sep 13. J Thorac Cardiovasc Surg. 2013. PMID: 22982037 Free PMC article.
108 results