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The genetic architecture of plasma kynurenine includes cardiometabolic disease mechanisms associated with the SH2B3 gene.
Bagheri M, Wang C, Shi M, Manouchehri A, Murray KT, Murphy MB, Shaffer CM, Singh K, Davis LK, Jarvik GP, Stanaway IB, Hebbring S, Reilly MP, Gerszten RE, Wang TJ, Mosley JD, Ferguson JF. Bagheri M, et al. Among authors: wang tj, wang c. Sci Rep. 2021 Aug 2;11(1):15652. doi: 10.1038/s41598-021-95154-9. Sci Rep. 2021. PMID: 34341450 Free PMC article.
Genetic Architecture of Plasma Alpha-Aminoadipic Acid Reveals a Relationship With High-Density Lipoprotein Cholesterol.
Shi M, Wang C, Mei H, Temprosa M, Florez JC, Tripputi M, Merino J, Lipworth L, Shu XO, Gerszten RE, Wang TJ, Beckman JA, Gamboa JL, Mosley JD, Ferguson JF; Diabetes Prevention Program Research Group. Shi M, et al. Among authors: wang tj, wang c. J Am Heart Assoc. 2022 Jun 7;11(11):e024388. doi: 10.1161/JAHA.121.024388. Epub 2022 May 27. J Am Heart Assoc. 2022. PMID: 35621206 Free PMC article.
Association of alpha-aminoadipic acid (2-AAA) with cardiometabolic risk factors in healthy and high-risk individuals.
Desine S, Gabriel CL, Smith HM, Antonetti OR, Wang C, Calcutt MW, Doran AC, Silver HJ, Nair S, Terry JG, Carr JJ, Linton MF, Brown JD, Koethe JR, Ferguson JF. Desine S, et al. Among authors: wang c. medRxiv [Preprint]. 2023 Jun 6:2023.06.05.23290990. doi: 10.1101/2023.06.05.23290990. medRxiv. 2023. Update in: Front Endocrinol (Lausanne). 2023 Sep 07;14:1122391. doi: 10.3389/fendo.2023.1122391 PMID: 37333170 Free PMC article. Updated. Preprint.
Association of alpha-aminoadipic acid with cardiometabolic risk factors in healthy and high-risk individuals.
Desine S, Gabriel CL, Smith HM, Antonetti OR, Wang C, Calcutt MW, Doran AC, Silver HJ, Nair S, Terry JG, Carr JJ, Linton MF, Brown JD, Koethe JR, Ferguson JF. Desine S, et al. Among authors: wang c. Front Endocrinol (Lausanne). 2023 Sep 7;14:1122391. doi: 10.3389/fendo.2023.1122391. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37745703 Free PMC article.
The consumption of animal products is associated with plasma levels of alpha-aminoadipic acid (2-AAA).
Antonetti OR, Desine S, Smith HM, Robles ME, McDonald E, Ovide G, Wang C, Dean ED, Doran AC, Calcutt MW, Huang S, Brown JD, Silver HJ, Ferguson JF. Antonetti OR, et al. Among authors: wang c. Nutr Metab Cardiovasc Dis. 2024 Jul;34(7):1712-1720. doi: 10.1016/j.numecd.2024.03.009. Epub 2024 Mar 12. Nutr Metab Cardiovasc Dis. 2024. PMID: 38658223 Free PMC article. Clinical Trial.
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