Elgersma Y - Search Results

1

Antisense oligonucleotide treatment rescues UBE3A expression and multiple phenotypes of an Angelman syndrome mouse model.

Milazzo C, Mientjes EJ, Wallaard I, Rasmussen SV, Erichsen KD, Kakunuri T, van der Sman ASE, Kremer T, Miller MT, Hoener MC, Elgersma Y. Milazzo C, et al. Among authors: elgersma y. JCI Insight. 2021 Aug 9;6(15):e145991. doi: 10.1172/jci.insight.145991. JCI Insight. 2021. PMID: 34369389 Free PMC article.

2

Rescue of neurological deficits in a mouse model for Angelman syndrome by reduction of alphaCaMKII inhibitory phosphorylation.

van Woerden GM, Harris KD, Hojjati MR, Gustin RM, Qiu S, de Avila Freire R, Jiang YH, Elgersma Y, Weeber EJ. van Woerden GM, et al. Among authors: elgersma y. Nat Neurosci. 2007 Mar;10(3):280-2. doi: 10.1038/nn1845. Epub 2007 Jan 28. Nat Neurosci. 2007. PMID: 17259980

3

Ube3a reinstatement identifies distinct developmental windows in a murine Angelman syndrome model.

Silva-Santos S, van Woerden GM, Bruinsma CF, Mientjes E, Jolfaei MA, Distel B, Kushner SA, Elgersma Y. Silva-Santos S, et al. Among authors: elgersma y. J Clin Invest. 2015 May;125(5):2069-76. doi: 10.1172/JCI80554. Epub 2015 Apr 13. J Clin Invest. 2015. PMID: 25866966 Free PMC article.

4

HCN channels are a novel therapeutic target for cognitive dysfunction in Neurofibromatosis type 1.

Omrani A, van der Vaart T, Mientjes E, van Woerden GM, Hojjati MR, Li KW, Gutmann DH, Levelt CN, Smit AB, Silva AJ, Kushner SA, Elgersma Y. Omrani A, et al. Among authors: elgersma y. Mol Psychiatry. 2015 Nov;20(11):1311-21. doi: 10.1038/mp.2015.48. Epub 2015 Apr 28. Mol Psychiatry. 2015. PMID: 25917366 Free PMC article.

5

GABAergic Neuron-Specific Loss of Ube3a Causes Angelman Syndrome-Like EEG Abnormalities and Enhances Seizure Susceptibility.

Judson MC, Wallace ML, Sidorov MS, Burette AC, Gu B, van Woerden GM, King IF, Han JE, Zylka MJ, Elgersma Y, Weinberg RJ, Philpot BD. Judson MC, et al. Among authors: elgersma y. Neuron. 2016 Apr 6;90(1):56-69. doi: 10.1016/j.neuron.2016.02.040. Epub 2016 Mar 24. Neuron. 2016. PMID: 27021170 Free PMC article.

6

Ube3a loss increases excitability and blunts orientation tuning in the visual cortex of Angelman syndrome model mice.

Wallace ML, van Woerden GM, Elgersma Y, Smith SL, Philpot BD. Wallace ML, et al. Among authors: elgersma y. J Neurophysiol. 2017 Jul 1;118(1):634-646. doi: 10.1152/jn.00618.2016. Epub 2017 May 3. J Neurophysiol. 2017. PMID: 28468997 Free PMC article.

7

Improvement of ubiquitylation site detection by Orbitrap mass spectrometry.

van der Wal L, Bezstarosti K, Sap KA, Dekkers DHW, Rijkers E, Mientjes E, Elgersma Y, Demmers JAA. van der Wal L, et al. Among authors: elgersma y. J Proteomics. 2018 Feb 10;172:49-56. doi: 10.1016/j.jprot.2017.10.014. Epub 2017 Nov 6. J Proteomics. 2018. PMID: 29122726 Free article.

8

Adult Ube3a Gene Reinstatement Restores the Electrophysiological Deficits of Prefrontal Cortex Layer 5 Neurons in a Mouse Model of Angelman Syndrome.

Rotaru DC, van Woerden GM, Wallaard I, Elgersma Y. Rotaru DC, et al. Among authors: elgersma y. J Neurosci. 2018 Sep 12;38(37):8011-8030. doi: 10.1523/JNEUROSCI.0083-18.2018. Epub 2018 Aug 6. J Neurosci. 2018. PMID: 30082419 Free PMC article.

9

The intellectual disability-associated CAMK2G p.Arg292Pro mutation acts as a pathogenic gain-of-function.

Proietti Onori M, Koopal B, Everman DB, Worthington JD, Jones JR, Ploeg MA, Mientjes E, van Bon BW, Kleefstra T, Schulman H, Kushner SA, Küry S, Elgersma Y, van Woerden GM. Proietti Onori M, et al. Among authors: elgersma y. Hum Mutat. 2018 Dec;39(12):2008-2024. doi: 10.1002/humu.23647. Epub 2018 Sep 19. Hum Mutat. 2018. PMID: 30184290 Free PMC article.

10

A behavioral test battery for mouse models of Angelman syndrome: a powerful tool for testing drugs and novel Ube3a mutants.

Sonzogni M, Wallaard I, Santos SS, Kingma J, du Mee D, van Woerden GM, Elgersma Y. Sonzogni M, et al. Among authors: elgersma y. Mol Autism. 2018 Sep 14;9:47. doi: 10.1186/s13229-018-0231-7. eCollection 2018. Mol Autism. 2018. PMID: 30220990 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

174 results

Search Page

Filters