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Page 1
The ubiquitin-editing enzyme A20 controls NK cell homeostasis through regulation of mTOR activity and TNF.
Vetters J, van Helden MJ, Wahlen S, Tavernier SJ, Martens A, Fayazpour F, Vergote K, Vanheerswynghels M, Deswarte K, Van Moorleghem J, De Prijck S, Takahashi N, Vandenabeele P, Boon L, van Loo G, Vivier E, Lambrecht BN, Janssens S. Vetters J, et al. Among authors: fayazpour f. J Exp Med. 2019 Sep 2;216(9):2010-2023. doi: 10.1084/jem.20182164. Epub 2019 Jul 11. J Exp Med. 2019. PMID: 31296735 Free PMC article.
The ORMDL3 asthma susceptibility gene regulates systemic ceramide levels without altering key asthma features in mice.
Debeuf N, Zhakupova A, Steiner R, Van Gassen S, Deswarte K, Fayazpour F, Van Moorleghem J, Vergote K, Pavie B, Lemeire K, Hammad H, Hornemann T, Janssens S, Lambrecht BN. Debeuf N, et al. Among authors: fayazpour f. J Allergy Clin Immunol. 2019 Dec;144(6):1648-1659.e9. doi: 10.1016/j.jaci.2019.06.041. Epub 2019 Jul 20. J Allergy Clin Immunol. 2019. PMID: 31330218 Free PMC article.
LXR signaling controls homeostatic dendritic cell maturation.
Bosteels V, Maréchal S, De Nolf C, Rennen S, Maelfait J, Tavernier SJ, Vetters J, Van De Velde E, Fayazpour F, Deswarte K, Lamoot A, Van Duyse J, Martens L, Bosteels C, Roelandt R, Emmaneel A, Van Gassen S, Boon L, Van Isterdael G, Guillas I, Vandamme N, Höglinger D, De Geest BG, Le Goff W, Saeys Y, Ravichandran KS, Lambrecht BN, Janssens S. Bosteels V, et al. Among authors: fayazpour f. Sci Immunol. 2023 May 12;8(83):eadd3955. doi: 10.1126/sciimmunol.add3955. Epub 2023 May 12. Sci Immunol. 2023. PMID: 37172103
STE20 kinase TAOK3 regulates type 2 immunity and metabolism in obesity.
Maes B, Fayazpour F, Catrysse L, Lornet G, Van De Velde E, De Wolf C, De Prijck S, Van Moorleghem J, Vanheerswynghels M, Deswarte K, Descamps B, Vanhove C, Van der Schueren B, Vangoitsenhoven R, Hammad H, Janssens S, Lambrecht BN. Maes B, et al. Among authors: fayazpour f. J Exp Med. 2023 Sep 4;220(9):e20210788. doi: 10.1084/jem.20210788. Epub 2023 Jun 22. J Exp Med. 2023. PMID: 37347461 Free PMC article.
Canonical IRE1 function needed to sustain vigorous natural killer cell proliferation during viral infection.
Vetters J, van Helden M, De Nolf C, Rennen S, Cloots E, Van De Velde E, Fayazpour F, Van Moorleghem J, Vanheerswynghels M, Vergote K, Boon L, Vivier E, Lambrecht BN, Janssens S. Vetters J, et al. Among authors: fayazpour f. iScience. 2023 Nov 23;26(12):108570. doi: 10.1016/j.isci.2023.108570. eCollection 2023 Dec 15. iScience. 2023. PMID: 38162021 Free PMC article.