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Page 1
A systems-level analysis highlights microglial activation as a modifying factor in common epilepsies.
Altmann A, Ryten M, Di Nunzio M, Ravizza T, Tolomeo D, Reynolds RH, Somani A, Bacigaluppi M, Iori V, Micotti E, Di Sapia R, Cerovic M, Palma E, Ruffolo G, Botía JA, Absil J, Alhusaini S, Alvim MKM, Auvinen P, Bargallo N, Bartolini E, Bender B, Bergo FPG, Bernardes T, Bernasconi A, Bernasconi N, Bernhardt BC, Blackmon K, Braga B, Caligiuri ME, Calvo A, Carlson C, Carr SJA, Cavalleri GL, Cendes F, Chen J, Chen S, Cherubini A, Concha L, David P, Delanty N, Depondt C, Devinsky O, Doherty CP, Domin M, Focke NK, Foley S, Franca W, Gambardella A, Guerrini R, Hamandi K, Hibar DP, Isaev D, Jackson GD, Jahanshad N, Kälviäinen R, Keller SS, Kochunov P, Kotikalapudi R, Kowalczyk MA, Kuzniecky R, Kwan P, Labate A, Langner S, Lenge M, Liu M, Martin P, Mascalchi M, Meletti S, Morita-Sherman ME, O'Brien TJ, Pariente JC, Richardson MP, Rodriguez-Cruces R, Rummel C, Saavalainen T, Semmelroch MK, Severino M, Striano P, Thesen T, Thomas RH, Tondelli M, Tortora D, Vaudano AE, Vivash L, von Podewils F, Wagner J, Weber B, Wiest R, Yasuda CL, Zhang G, Zhang J; ENIGMA-Epilepsy Working Group; Leu C, Avbersek A; EpiPGX Consortium; Thom M, Whelan CD, Thompson P, McDonald CR, Vezzani A, Sisodiya SM. Altmann A, et al. Among authors: di sapia r. Neuropathol Appl Neurobiol. 2022 Feb;48(1):e12758. doi: 10.1111/nan.12758. Epub 2021 Sep 5. Neuropathol Appl Neurobiol. 2022. PMID: 34388852 Free PMC article.
Cholesterol 24-hydroxylase is a novel pharmacological target for anti-ictogenic and disease modification effects in epilepsy.
Salamone A, Terrone G, Di Sapia R, Balosso S, Ravizza T, Beltrame L, Craparotta I, Mannarino L, Cominesi SR, Rizzi M, Pauletti A, Marchini S, Porcu L, Zimmer TS, Aronica E, During M, Abrahams B, Kondo S, Nishi T, Vezzani A. Salamone A, et al. Among authors: di sapia r. Neurobiol Dis. 2022 Oct 15;173:105835. doi: 10.1016/j.nbd.2022.105835. Epub 2022 Aug 3. Neurobiol Dis. 2022. PMID: 35932989 Free article.
WONOEP appraisal: Modeling early onset epilepsies.
De Meulemeester AS, Reid C, Auvin S, Carlen PL, Cole AJ, Szlendak R, Di Sapia R, Moshé SL, Sankar R, O'Brien TJ, Baulac S, Henshall DC, Akman Ö, Galanopoulou AS. De Meulemeester AS, et al. Among authors: di sapia r. Epilepsia. 2024 Sep;65(9):2553-2566. doi: 10.1111/epi.18063. Epub 2024 Jul 23. Epilepsia. 2024. PMID: 39042520 Review.
Early treatment with rifaximin during epileptogenesis reverses gut alterations and reduces seizure duration in a mouse model of acquired epilepsy.
Kebede V, Ravizza T, Balosso S, Di Sapia R, Canali L, Soldi S, Galletti S, Papazlatani C, Karas PA, Vasileiadis S, Sforzini A, Pasetto L, Bonetto V, Vezzani A, Vesci L. Kebede V, et al. Among authors: di sapia r. Brain Behav Immun. 2024 Jul;119:363-380. doi: 10.1016/j.bbi.2024.04.007. Epub 2024 Apr 10. Brain Behav Immun. 2024. PMID: 38608741 Free article.
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