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Page 1
The Tunicate Metabolite 2-(3,5-Diiodo-4-methoxyphenyl)ethan-1-amine Targets Ion Channels of Vertebrate Sensory Neurons.
Paguigan ND, Yan Y, Karthikeyan M, Chase K, Carter J, Leavitt LS, Lim AL, Lin Z, Memon T, Christensen S, Bentzen BH, Schmitt N, Reilly CA, Teichert RW, Raghuraman S, Olivera BM, Schmidt EW. Paguigan ND, et al. Among authors: leavitt ls. ACS Chem Biol. 2021 Sep 17;16(9):1654-1662. doi: 10.1021/acschembio.1c00328. Epub 2021 Aug 23. ACS Chem Biol. 2021. PMID: 34423964
Conotoxin κM-RIIIJ, a tool targeting asymmetric heteromeric Kv1 channels.
Cordeiro S, Finol-Urdaneta RK, Köpfer D, Markushina A, Song J, French RJ, Kopec W, de Groot BL, Giacobassi MJ, Leavitt LS, Raghuraman S, Teichert RW, Olivera BM, Terlau H. Cordeiro S, et al. Among authors: leavitt ls. Proc Natl Acad Sci U S A. 2019 Jan 15;116(3):1059-1064. doi: 10.1073/pnas.1813161116. Epub 2018 Dec 28. Proc Natl Acad Sci U S A. 2019. PMID: 30593566 Free PMC article.
Neuroactive Type-A γ-Aminobutyric Acid Receptor Allosteric Modulator Steroids from the Hypobranchial Gland of Marine Mollusk, Conus geographus.
Niu C, Leavitt LS, Lin Z, Paguigan ND, Sun L, Zhang J, Torres JP, Raghuraman S, Chase K, Cadeddu R, Karthikeyan M, Bortolato M, Reilly CA, Hughen RW, Light AR, Olivera BM, Schmidt EW. Niu C, et al. Among authors: leavitt ls. J Med Chem. 2021 May 27;64(10):7033-7043. doi: 10.1021/acs.jmedchem.1c00562. Epub 2021 May 5. J Med Chem. 2021. PMID: 33949869
Nicotinic Acetylcholine Receptor Partial Antagonist Polyamides from Tunicates and Their Predatory Sea Slugs.
Paguigan ND, Tun JO, Leavitt LS, Lin Z, Chase K, Dowell C, Deering-Rice CE, Lim AL, Karthikeyan M, Hughen RW, Zhang J, Peterson RT, Reilly CA, Light AR, Raghuraman S, McIntosh JM, Olivera BM, Schmidt EW. Paguigan ND, et al. Among authors: leavitt ls. ACS Chem Neurosci. 2021 Jul 21;12(14):2693-2704. doi: 10.1021/acschemneuro.1c00345. Epub 2021 Jul 2. ACS Chem Neurosci. 2021. PMID: 34213884 Free PMC article.
Using Constellation Pharmacology to Characterize a Novel α-Conotoxin from Conus ateralbus.
Neves JLB, Urcino C, Chase K, Dowell C, Hone AJ, Morgenstern D, Chua VM, Ramiro IBL, Imperial JS, Leavitt LS, Phan J, Fisher FA, Watkins M, Raghuraman S, Tun JO, Ueberheide BM, McIntosh JM, Vasconcelos V, Olivera BM, Gajewiak J. Neves JLB, et al. Among authors: leavitt ls. Mar Drugs. 2024 Feb 29;22(3):118. doi: 10.3390/md22030118. Mar Drugs. 2024. PMID: 38535458 Free PMC article.