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Macrophage-derived IL-6 trans-signalling as a novel target in the pathogenesis of bronchopulmonary dysplasia.
Hirani D, Alvira CM, Danopoulos S, Milla C, Donato M, Tian L, Mohr J, Dinger K, Vohlen C, Selle J, V Koningsbruggen-Rietschel S, Barbarino V, Pallasch C, Rose-John S, Odenthal M, Pryhuber GS, Mansouri S, Savai R, Seeger W, Khatri P, Al Alam D, Dötsch J, Alejandre Alcazar MA. Hirani D, et al. Among authors: mohr j. Eur Respir J. 2022 Feb 17;59(2):2002248. doi: 10.1183/13993003.02248-2020. Print 2022 Feb. Eur Respir J. 2022. PMID: 34446466 Free PMC article.
Elafin Treatment Rescues EGFR-Klf4 Signaling and Lung Cell Survival in Ventilated Newborn Mice.
Alejandre Alcazar MA, Kaschwich M, Ertsey R, Preuss S, Milla C, Mujahid S, Masumi J, Khan S, Mokres LM, Tian L, Mohr J, Hirani DV, Rabinovitch M, Bland RD. Alejandre Alcazar MA, et al. Among authors: mohr j. Am J Respir Cell Mol Biol. 2018 Nov;59(5):623-634. doi: 10.1165/rcmb.2017-0332OC. Am J Respir Cell Mol Biol. 2018. PMID: 29894205 Free PMC article.
IL-6/Smad2 signaling mediates acute kidney injury and regeneration in a murine model of neonatal hyperoxia.
Mohr J, Voggel J, Vohlen C, Dinger K, Dafinger C, Fink G, Göbel H, Liebau MC, Dötsch J, Alejandre Alcazar MA. Mohr J, et al. FASEB J. 2019 May;33(5):5887-5902. doi: 10.1096/fj.201801875RR. Epub 2019 Feb 5. FASEB J. 2019. PMID: 30721632
The amenability of these pathways to pharmacological approaches may offer new avenues to protect premature infants from CKD.-Mohr, J., Voggel, J., Vohlen, C., Dinger, K., Dafinger, C., Fink, G., Gobel, H., Liebau, M. C., Dotsch, J., Alejandre Alcazar, …
The amenability of these pathways to pharmacological approaches may offer new avenues to protect premature infants from CKD.-Mohr, …
Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO1-axis in later life.
Selle J, Dinger K, Jentgen V, Zanetti D, Will J, Georgomanolis T, Vohlen C, Wilke R, Kojonazarov B, Klymenko O, Mohr J, V Koningsbruggen-Rietschel S, Rhodes CJ, Ulrich A, Hirani D, Nestler T, Odenthal M, Mahabir E, Nayakanti S, Dabral S, Wunderlich T, Priest J, Seeger W, Dötsch J, Pullamsetti SS, Alejandre Alcazar MA. Selle J, et al. Among authors: mohr j. Nat Commun. 2022 Jul 27;13(1):4352. doi: 10.1038/s41467-022-31655-z. Nat Commun. 2022. PMID: 35896539 Free PMC article.
CXCL10 deficiency limits macrophage infiltration, preserves lung matrix, and enables lung growth in bronchopulmonary dysplasia.
Hirani DV, Thielen F, Mansouri S, Danopoulos S, Vohlen C, Haznedar-Karakaya P, Mohr J, Wilke R, Selle J, Grosch T, Mizik I, Odenthal M, Alvira CM, Kuiper-Makris C, Pryhuber GS, Pallasch C, van Koningsbruggen-Rietschel S, Al-Alam D, Seeger W, Savai R, Dötsch J, Alejandre Alcazar MA. Hirani DV, et al. Among authors: mohr j. Inflamm Regen. 2023 Oct 24;43(1):52. doi: 10.1186/s41232-023-00301-6. Inflamm Regen. 2023. PMID: 37876024 Free PMC article.
1,036 results