Gagne R - Search Results

1

Potency Ranking of Per- and Polyfluoroalkyl Substances Using High-Throughput Transcriptomic Analysis of Human Liver Spheroids.

Reardon AJF, Rowan-Carroll A, Ferguson SS, Leingartner K, Gagne R, Kuo B, Williams A, Lorusso L, Bourdon-Lacombe JA, Carrier R, Moffat I, Yauk CL, Atlas E. Reardon AJF, et al. Among authors: gagne r. Toxicol Sci. 2021 Oct 27;184(1):154-169. doi: 10.1093/toxsci/kfab102. Toxicol Sci. 2021. PMID: 34453843

2

High-Throughput Transcriptomic Analysis of Human Primary Hepatocyte Spheroids Exposed to Per- and Polyfluoroalkyl Substances as a Platform for Relative Potency Characterization.

Rowan-Carroll A, Reardon A, Leingartner K, Gagné R, Williams A, Meier MJ, Kuo B, Bourdon-Lacombe J, Moffat I, Carrier R, Nong A, Lorusso L, Ferguson SS, Atlas E, Yauk C. Rowan-Carroll A, et al. Among authors: gagne r. Toxicol Sci. 2021 May 27;181(2):199-214. doi: 10.1093/toxsci/kfab039. Toxicol Sci. 2021. PMID: 33772556

3

A Modern Genotoxicity Testing Paradigm: Integration of the High-Throughput CometChip® and the TGx-DDI Transcriptomic Biomarker in Human HepaRG™ Cell Cultures.

Buick JK, Williams A, Meier MJ, Swartz CD, Recio L, Gagné R, Ferguson SS, Engelward BP, Yauk CL. Buick JK, et al. Among authors: gagne r. Front Public Health. 2021 Aug 18;9:694834. doi: 10.3389/fpubh.2021.694834. eCollection 2021. Front Public Health. 2021. PMID: 34485225 Free PMC article.

4

Impact of Genomics Platform and Statistical Filtering on Transcriptional Benchmark Doses (BMD) and Multiple Approaches for Selection of Chemical Point of Departure (PoD).

Webster AF, Chepelev N, Gagné R, Kuo B, Recio L, Williams A, Yauk CL. Webster AF, et al. Among authors: gagne r. PLoS One. 2015 Aug 27;10(8):e0136764. doi: 10.1371/journal.pone.0136764. eCollection 2015. PLoS One. 2015. PMID: 26313361 Free PMC article.

5

Transcriptional Profiling of Dibenzo[def,p]chrysene-induced Spleen Atrophy Provides Mechanistic Insights into its Immunotoxicity in MutaMouse.

Chepelev NL, Long AS, Williams A, Kuo B, Gagné R, Kennedy DA, Phillips DH, Arlt VM, White PA, Yauk CL. Chepelev NL, et al. Among authors: gagne r. Toxicol Sci. 2016 Jan;149(1):251-68. doi: 10.1093/toxsci/kfv232. Epub 2015 Oct 24. Toxicol Sci. 2016. PMID: 26496743

6

Demodifying RNA for Transcriptomic Analyses of Archival Formalin-Fixed Paraffin-Embedded Samples.

Wehmas LC, Wood CE, Gagne R, Williams A, Yauk C, Gosink MM, Dalmas D, Hao R, O'Lone R, Hester S. Wehmas LC, et al. Among authors: gagne r. Toxicol Sci. 2018 Apr 1;162(2):535-547. doi: 10.1093/toxsci/kfx278. Toxicol Sci. 2018. PMID: 29228314 Free PMC article.

7

The use of in vitro transcriptional data to identify thresholds of effects in a human lens epithelial cell-line exposed to ionizing radiation.

Chauhan V, Rowan-Carroll A, Gagné R, Kuo B, Williams A, Yauk CL. Chauhan V, et al. Among authors: gagne r. Int J Radiat Biol. 2019 Feb;95(2):156-169. doi: 10.1080/09553002.2019.1539883. Epub 2018 Nov 29. Int J Radiat Biol. 2019. PMID: 30395761

8

Hepatic transcriptional dose-response analysis of male and female Fischer rats exposed to hexabromocyclododecane.

Farmahin R, Gannon AM, Gagné R, Rowan-Carroll A, Kuo B, Williams A, Curran I, Yauk CL. Farmahin R, et al. Among authors: gagne r. Food Chem Toxicol. 2019 Nov;133:110262. doi: 10.1016/j.fct.2018.12.032. Epub 2018 Dec 27. Food Chem Toxicol. 2019. PMID: 30594549 Free article.

9

Flow cytometric micronucleus assay and TGx-DDI transcriptomic biomarker analysis of ten genotoxic and non-genotoxic chemicals in human HepaRG™ cells.

Buick JK, Williams A, Gagné R, Swartz CD, Recio L, Ferguson SS, Yauk CL. Buick JK, et al. Among authors: gagne r. Genes Environ. 2020 Feb 4;42:5. doi: 10.1186/s41021-019-0139-2. eCollection 2020. Genes Environ. 2020. PMID: 32042365 Free PMC article.

10

Transcriptomic pathway and benchmark dose analysis of Bisphenol A, Bisphenol S, Bisphenol F, and 3,3',5,5'-Tetrabromobisphenol A in H9 human embryonic stem cells.

Peshdary V, Hobbs CA, Maynor T, Shepard K, Gagné R, Williams A, Kuo B, Chepelev N, Recio L, Yauk C, Atlas E. Peshdary V, et al. Among authors: gagne r. Toxicol In Vitro. 2021 Apr;72:105097. doi: 10.1016/j.tiv.2021.105097. Epub 2021 Jan 18. Toxicol In Vitro. 2021. PMID: 33476716

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