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Page 1
In vivo Treatment of a Severe Vascular Disease via a Bespoke CRISPR-Cas9 Base Editor.
Alves CRR, Das S, Krishnan V, Ha LL, Fox LR, Stutzman HE, Shamber CE, Kalailingam P, McCarthy S, Cardenas CLL, Fong CE, Imai T, Mitra S, Yun S, Wood RK, Benning FMC, Lawton J, Kim N, Silverstein RA, Ferreira da Silva J, de la Cruz D, Richa R, Malhotra R, Chung DY, Chao LH, Tsai SQ, Maguire CA, Lindsay ME, Kleinstiver BP, Musolino PL. Alves CRR, et al. Among authors: de la cruz d. bioRxiv [Preprint]. 2024 Nov 11:2024.11.11.621817. doi: 10.1101/2024.11.11.621817. bioRxiv. 2024. PMID: 39605323 Free PMC article. Preprint.
Maternal exercise opportunity before, during, and after pregnancy alters maternal care behavior and offspring development and survival, but has few effects on offspring physical activity or body composition.
Schwartz NE, Schmill MP, Cadney MD, Castro AA, Hillis DA, McNamara MP, Rashid JO, Lampman W, DeLaCruz DF, Tran BD, Trutalli NL, Garland T Jr. Schwartz NE, et al. Physiol Behav. 2024 Nov 14:114752. doi: 10.1016/j.physbeh.2024.114752. Online ahead of print. Physiol Behav. 2024. PMID: 39549866 Free article.
Expression-based selection identifies a microglia-tropic AAV capsid for direct and CSF routes of administration in mice.
Santoscoy MC, Espinoza P, Hanlon KS, Yang L, Nieland L, Ng C, Badr CE, Hickman S, de la Cruz D, Griciuc A, Elkhoury J, Bennett RE, Shen S, Maguire CA. Santoscoy MC, et al. Among authors: de la cruz d. bioRxiv [Preprint]. 2024 Sep 27:2024.09.25.614546. doi: 10.1101/2024.09.25.614546. bioRxiv. 2024. PMID: 39386560 Free PMC article. Preprint.
In vivo selection in non-human primates identifies AAV capsids for on-target CSF delivery to spinal cord.
Hanlon KS, Cheng M, Ferrer RM, Ryu JR, Lee B, De La Cruz D, Patel N, Espinoza P, Santoscoy MC, Gong Y, Ng C, Nguyen DM, Nammour J, Clark SW, Heine VM, Sun W, Kozarsky K, Maguire CA. Hanlon KS, et al. Among authors: de la cruz d. Mol Ther. 2024 Aug 7;32(8):2584-2603. doi: 10.1016/j.ymthe.2024.05.040. Epub 2024 Jun 5. Mol Ther. 2024. PMID: 38845196 Free PMC article.
Effect of Early vs Late Inguinal Hernia Repair on Serious Adverse Event Rates in Preterm Infants: A Randomized Clinical Trial.
HIP Trial Investigators; Blakely ML, Krzyzaniak A, Dassinger MS, Pedroza C, Weitkamp JH, Gosain A, Cotten M, Hintz SR, Rice H, Courtney SE, Lally KP, Ambalavanan N, Bendel CM, Bui KCT, Calkins C, Chandler NM, Dasgupta R, Davis JM, Deans K, DeUgarte DA, Gander J, Jackson CA, Keszler M, Kling K, Fenton SJ, Fisher KA, Hartman T, Huang EY, Islam S, Koch F, Lainwala S, Lesher A, Lopez M, Misra M, Overbey J, Poindexter B, Russell R, Stylianos S, Tamura DY, Yoder BA, Lucas D, Shaul D, Ham PB 3rd, Fitzpatrick C, Calkins K, Garrison A, de la Cruz D, Abdessalam S, Kvasnovsky C, Segura BJ, Shilyansky J, Smith LM, Tyson JE. HIP Trial Investigators, et al. Among authors: de la cruz d. JAMA. 2024 Mar 26;331(12):1035-1044. doi: 10.1001/jama.2024.2302. JAMA. 2024. PMID: 38530261 Free PMC article. Clinical Trial.
Quark Mass Dependence of Heavy Quark Diffusion Coefficient from Lattice QCD.
Altenkort L, de la Cruz D, Kaczmarek O, Larsen R, Moore GD, Mukherjee S, Petreczky P, Shu HT, Stendebach S; HotQCD Collaboration. Altenkort L, et al. Among authors: de la cruz d. Phys Rev Lett. 2024 Feb 2;132(5):051902. doi: 10.1103/PhysRevLett.132.051902. Phys Rev Lett. 2024. PMID: 38364130
Optimization of base editors for the functional correction of SMN2 as a treatment for spinal muscular atrophy.
Alves CRR, Ha LL, Yaworski R, Sutton ER, Lazzarotto CR, Christie KA, Reilly A, Beauvais A, Doll RM, de la Cruz D, Maguire CA, Swoboda KJ, Tsai SQ, Kothary R, Kleinstiver BP. Alves CRR, et al. Among authors: de la cruz d. Nat Biomed Eng. 2024 Feb;8(2):118-131. doi: 10.1038/s41551-023-01132-z. Epub 2023 Dec 6. Nat Biomed Eng. 2024. PMID: 38057426 Free PMC article.
77 results