Lau K - Search Results

1

Monitoring cell-mediated immune responses in AAV gene therapy clinical trials using a validated IFN-γ ELISpot method.

Patton KS, Harrison MT, Long BR, Lau K, Holcomb J, Owen R, Kasprzyk T, Janetzki S, Zoog SJ, Vettermann C. Patton KS, et al. Among authors: lau k. Mol Ther Methods Clin Dev. 2021 May 29;22:183-195. doi: 10.1016/j.omtm.2021.05.012. eCollection 2021 Sep 10. Mol Ther Methods Clin Dev. 2021. PMID: 34485604 Free PMC article.

2

Association of immune response with efficacy and safety outcomes in adults with phenylketonuria administered pegvaliase in phase 3 clinical trials.

Gupta S, Lau K, Harding CO, Shepherd G, Boyer R, Atkinson JP, Knight V, Olbertz J, Larimore K, Gu Z, Li M, Rosen O, Zoog SJ, Weng HH, Schweighardt B. Gupta S, et al. Among authors: lau k. EBioMedicine. 2018 Nov;37:366-373. doi: 10.1016/j.ebiom.2018.10.038. Epub 2018 Oct 23. EBioMedicine. 2018. PMID: 30366815 Free PMC article. Clinical Trial.

3

Depletion of interfering IgG and IgM is critical to determine the role of IgE in pegvaliase-associated hypersensitivity.

Larimore K, Nguyen T, Badillo B, Lau K, Zori R, Shepherd G, Zoog SJ, Weng HH, Gupta S. Larimore K, et al. Among authors: lau k. J Immunol Methods. 2019 May;468:20-28. doi: 10.1016/j.jim.2019.03.004. Epub 2019 Mar 14. J Immunol Methods. 2019. PMID: 30880261

4

Early Phase Clinical Immunogenicity of Valoctocogene Roxaparvovec, an AAV5-Mediated Gene Therapy for Hemophilia A.

Long BR, Veron P, Kuranda K, Hardet R, Mitchell N, Hayes GM, Wong WY, Lau K, Li M, Hock MB, Zoog SJ, Vettermann C, Mingozzi F, Schweighardt B. Long BR, et al. Among authors: lau k. Mol Ther. 2021 Feb 3;29(2):597-610. doi: 10.1016/j.ymthe.2020.12.008. Epub 2020 Dec 10. Mol Ther. 2021. PMID: 33309883 Free PMC article.

5

Achieving efficacy in subjects with sustained pegvaliase-neutralizing antibody responses.

Aryal M, Lau K, Boyer R, Zhou H, Abend J, Gu K, Olbertz J, Gupta S, Zoog S, Larimore K. Aryal M, et al. Among authors: lau k. Mol Genet Metab. 2021 Nov;134(3):235-242. doi: 10.1016/j.ymgme.2021.09.006. Epub 2021 Oct 4. Mol Genet Metab. 2021. PMID: 34716085 Free article. Clinical Trial.

6

Clinical immunogenicity outcomes from GENEr8-1, a phase 3 study of valoctocogene roxaparvovec, an AAV5-vectored gene therapy for hemophilia A.

Long BR, Robinson TM, Day JRS, Yu H, Lau K, Imtiaz U, Patton KS, de Hart G, Henshaw J, Agarwal S, Vettermann C, Zoog SJ, Gupta S. Long BR, et al. Among authors: lau k. Mol Ther. 2024 Jul 3;32(7):2052-2063. doi: 10.1016/j.ymthe.2024.05.033. Epub 2024 May 24. Mol Ther. 2024. PMID: 38796703 Free article. Clinical Trial.

7

Biomarker analysis of Morquio syndrome: identification of disease state and drug responsive markers.

Martell L, Lau K, Mei M, Burnett V, Decker C, Foehr ED. Martell L, et al. Among authors: lau k. Orphanet J Rare Dis. 2011 Dec 16;6:84. doi: 10.1186/1750-1172-6-84. Orphanet J Rare Dis. 2011. PMID: 22176730 Free PMC article. Clinical Trial.

8

Immunogenicity of Elosulfase Alfa, an Enzyme Replacement Therapy in Patients With Morquio A Syndrome: Results From MOR-004, a Phase III Trial.

Schweighardt B, Tompkins T, Lau K, Jesaitis L, Qi Y, Musson DG, Farmer P, Haller C, Shaywitz AJ, Yang K, O'Neill CA. Schweighardt B, et al. Among authors: lau k. Clin Ther. 2015 May 1;37(5):1012-1021.e6. doi: 10.1016/j.clinthera.2014.11.005. Epub 2014 Dec 6. Clin Ther. 2015. PMID: 25487082 Clinical Trial.

9

Quantum error correction below the surface code threshold.

Google Quantum AI and Collaborators. Google Quantum AI and Collaborators. Nature. 2024 Dec 9. doi: 10.1038/s41586-024-08449-y. Online ahead of print. Nature. 2024. PMID: 39653125

10

Search for CP violation in

D^{0} \to K_{S}^{0} K_{S}^{0}

decays in proton-proton collisions at

\sqrt{s} = 13 Te V

.

CMS Collaboration. CMS Collaboration. Eur Phys J C Part Fields. 2024;84(12):1264. doi: 10.1140/epjc/s10052-024-13244-0. Epub 2024 Dec 6. Eur Phys J C Part Fields. 2024. PMID: 39651650 Free PMC article.

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