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A map of the altered glioma metabolism.
Deshmukh R, Allega MF, Tardito S. Deshmukh R, et al. Trends Mol Med. 2021 Nov;27(11):1045-1059. doi: 10.1016/j.molmed.2021.07.011. Epub 2021 Sep 3. Trends Mol Med. 2021. PMID: 34489164 Review.
An IDH1-vitamin C crosstalk drives human erythroid development by inhibiting pro-oxidant mitochondrial metabolism.
Gonzalez-Menendez P, Romano M, Yan H, Deshmukh R, Papoin J, Oburoglu L, Daumur M, Dumé AS, Phadke I, Mongellaz C, Qu X, Bories PN, Fontenay M, An X, Dardalhon V, Sitbon M, Zimmermann VS, Gallagher PG, Tardito S, Blanc L, Mohandas N, Taylor N, Kinet S. Gonzalez-Menendez P, et al. Among authors: deshmukh r. Cell Rep. 2021 Feb 2;34(5):108723. doi: 10.1016/j.celrep.2021.108723. Cell Rep. 2021. PMID: 33535038 Free PMC article.
Hepatic glutamine synthetase controls N5-methylglutamine in homeostasis and cancer.
Villar VH, Allega MF, Deshmukh R, Ackermann T, Nakasone MA, Vande Voorde J, Drake TM, Oetjen J, Bloom A, Nixon C, Müller M, May S, Tan EH, Vereecke L, Jans M, Blancke G, Murphy DJ, Huang DT, Lewis DY, Bird TG, Sansom OJ, Blyth K, Sumpton D, Tardito S. Villar VH, et al. Among authors: deshmukh r. Nat Chem Biol. 2023 Mar;19(3):292-300. doi: 10.1038/s41589-022-01154-9. Epub 2022 Oct 24. Nat Chem Biol. 2023. PMID: 36280791 Free PMC article.
Breast cancer secretes anti-ferroptotic MUFAs and depends on selenoprotein synthesis for metastasis.
Ackermann T, Shokry E, Deshmukh R, Anand J, Galbraith LCA, Mitchell L, Rodriguez-Blanco G, Villar VH, Sterken BA, Nixon C, Zanivan S, Blyth K, Sumpton D, Tardito S. Ackermann T, et al. Among authors: deshmukh r. EMBO Mol Med. 2024 Nov;16(11):2749-2774. doi: 10.1038/s44321-024-00142-x. Epub 2024 Oct 21. EMBO Mol Med. 2024. PMID: 39433871 Free PMC article.
593 results