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Intravenous administration of BCG protects mice against lethal SARS-CoV-2 challenge.
Hilligan KL, Namasivayam S, Clancy CS, O'Mard D, Oland SD, Robertson SJ, Baker PJ, Castro E, Garza NL, Lafont BAP, Johnson R, Ronchese F, Mayer-Barber KD, Best SM, Sher A. Hilligan KL, et al. Among authors: johnson r. bioRxiv [Preprint]. 2021 Aug 31:2021.08.30.458273. doi: 10.1101/2021.08.30.458273. bioRxiv. 2021. Update in: J Exp Med. 2022 Feb 7;219(2):e20211862. doi: 10.1084/jem.20211862 PMID: 34494021 Free PMC article. Updated. Preprint.
Characteristic and quantifiable COVID-19-like abnormalities in CT- and PET/CT-imaged lungs of SARS-CoV-2-infected crab-eating macaques (Macaca fascicularis).
Finch CL, Crozier I, Lee JH, Byrum R, Cooper TK, Liang J, Sharer K, Solomon J, Sayre PJ, Kocher G, Bartos C, Aiosa NM, Castro M, Larson PA, Adams R, Beitzel B, Di Paola N, Kugelman JR, Kurtz JR, Burdette T, Nason MC, Feuerstein IM, Palacios G, St Claire MC, Lackemeyer MG, Johnson RF, Braun KM, Ramuta MD, Wada J, Schmaljohn CS, Friedrich TC, O'Connor DH, Kuhn JH. Finch CL, et al. Among authors: johnson rf. bioRxiv [Preprint]. 2020 May 14:2020.05.14.096727. doi: 10.1101/2020.05.14.096727. bioRxiv. 2020. PMID: 32511338 Free PMC article. Preprint.
A single intranasal dose of a live-attenuated parainfluenza virus-vectored SARS-CoV-2 vaccine is protective in hamsters.
Liu X, Luongo C, Matsuoka Y, Park HS, Santos C, Yang L, Moore IN, Afroz S, Johnson RF, Lafont BAP, Martens C, Best SM, Munster VJ, Hollý J, Yewdell JW, Le Nouën C, Munir S, Buchholz UJ. Liu X, et al. Proc Natl Acad Sci U S A. 2021 Dec 14;118(50):e2109744118. doi: 10.1073/pnas.2109744118. Proc Natl Acad Sci U S A. 2021. PMID: 34876520 Free PMC article.
Intravenous administration of BCG protects mice against lethal SARS-CoV-2 challenge.
Hilligan KL, Namasivayam S, Clancy CS, O'Mard D, Oland SD, Robertson SJ, Baker PJ, Castro E, Garza NL, Lafont BAP, Johnson R, Ronchese F, Mayer-Barber KD, Best SM, Sher A. Hilligan KL, et al. Among authors: johnson r. J Exp Med. 2022 Feb 7;219(2):e20211862. doi: 10.1084/jem.20211862. Epub 2021 Dec 10. J Exp Med. 2022. PMID: 34889942 Free PMC article.
Extremely potent monoclonal antibodies neutralize Omicron and other SARS-CoV-2 variants.
Chen Z, Zhang P, Matsuoka Y, Tsybovsky Y, West K, Santos C, Boyd LF, Nguyen H, Pomerenke A, Stephens T, Olia AS, De Giorgi V, Holbrook MR, Gross R, Postnikova E, Garza NL, Johnson RF, Margulies DH, Kwong PD, Alter HJ, Buchholz UJ, Lusso P, Farci P. Chen Z, et al. Among authors: johnson rf. medRxiv [Preprint]. 2022 Jan 13:2022.01.12.22269023. doi: 10.1101/2022.01.12.22269023. medRxiv. 2022. Update in: Cell Rep. 2022 Nov 1;41(5):111528. doi: 10.1016/j.celrep.2022.111528 PMID: 35043120 Free PMC article. Updated. Preprint.
Mild SARS-CoV-2 infection in rhesus macaques is associated with viral control prior to antigen-specific T cell responses in tissues.
Nelson CE, Namasivayam S, Foreman TW, Kauffman KD, Sakai S, Dorosky DE, Lora NE; NIAID/DIR Tuberculosis Imaging Program; Brooks K, Potter EL, Garza NL, Lafont BAP, Johnson RF, Roederer M, Sher A, Weiskopf D, Sette A, de Wit E, Hickman HD, Brenchley JM, Via LE, Barber DL. Nelson CE, et al. Sci Immunol. 2022 Mar 10:eabo0535. doi: 10.1126/sciimmunol.abo0535. Online ahead of print. Sci Immunol. 2022. PMID: 35271298 Free PMC article.
Intranasal pediatric parainfluenza virus-vectored SARS-CoV-2 vaccine candidate is protective in macaques.
Nouën CL, Nelson CE, Liu X, Park HS, Matsuoka Y, Luongo C, Santos C, Yang L, Herbert R, Castens A, Moore IN, Wilder-Kofie T, Moore R, Walker A, Zhang P, Lusso P, Johnson RF, Garza NL, Via LE, Munir S, Barber D, Buchholz UJ. Nouën CL, et al. Among authors: johnson rf. bioRxiv [Preprint]. 2022 May 23:2022.05.21.492923. doi: 10.1101/2022.05.21.492923. bioRxiv. 2022. Update in: Proc Natl Acad Sci U S A. 2021 Dec 14;118(50):e2109744118. doi: 10.1073/pnas.2109744118 PMID: 35665011 Free PMC article. Updated. Preprint.
Intranasal immunization with avian paramyxovirus type 3 expressing SARS-CoV-2 spike protein protects hamsters against SARS-CoV-2.
Park HS, Matsuoka Y, Luongo C, Yang L, Santos C, Liu X, Ahlers LRH, Moore IN, Afroz S, Johnson RF, Lafont BAP, Dorward DW, Fischer ER, Martens C, Samal SK, Munir S, Buchholz UJ, Le Nouën C. Park HS, et al. Among authors: johnson rf. NPJ Vaccines. 2022 Jun 28;7(1):72. doi: 10.1038/s41541-022-00493-x. NPJ Vaccines. 2022. PMID: 35764659 Free PMC article.
IL-10 suppresses T cell expansion while promoting tissue-resident memory cell formation during SARS-CoV-2 infection in rhesus macaques.
Nelson CE, Foreman TW, Kauffman KD, Sakai S, Gould ST, Fleegle JD, Gomez F; NIAID/DIR Tuberculosis Imaging Program; Le Nouën C, Liu X, Burdette TL, Garza NL, Lafont BAP, Brooks K, Arlehamn CSL, Weiskopf D, Sette A, Hickman HD, Buchholz UJ, Johnson RF, Brenchley JM, Via LE, Barber DL. Nelson CE, et al. bioRxiv [Preprint]. 2022 Sep 15:2022.09.13.507852. doi: 10.1101/2022.09.13.507852. bioRxiv. 2022. Update in: PLoS Pathog. 2024 Jul 1;20(7):e1012339. doi: 10.1371/journal.ppat.1012339 PMID: 36172119 Free PMC article. Updated. Preprint.
Evaluation of endogenous and therapeutic 25-hydroxycholesterols in murine models of pulmonary SARS-CoV-2 infection.
Fessler MB, Madenspacher J, Baker PJ, Hilligan KL, Castro E, Meacham J, Chen SH, Johnson RF, Martin NP, Tucker CJ, Mahapatra D, Cesta M, Mayer-Barber KD. Fessler MB, et al. bioRxiv [Preprint]. 2022 Sep 13:2022.09.12.507671. doi: 10.1101/2022.09.12.507671. bioRxiv. 2022. Update in: Am J Respir Cell Mol Biol. 2023 Dec;69(6):638-648. doi: 10.1165/rcmb.2023-0007OC PMID: 36263064 Free PMC article. Updated. Preprint.
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