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The potent and selective RIPK2 inhibitor BI 706039 improves intestinal inflammation in the TRUC mouse model of inflammatory bowel disease.
Ermann J, Matmusaev M, Haley EK, Braun C, Jost F, Mayer-Wrangowski S, Hsiao P, Ting N, Li L, Terenzio D, Chime J, Lukas S, Patnaude L, Panzenbeck M, Csordas D, Zheng J, Mierz D, Simpson T, King FJ, Klimowicz AP, Mbow ML, Fine JS, Miller CA, Fogal SE, Byrne FR. Ermann J, et al. Among authors: mierz d. Am J Physiol Gastrointest Liver Physiol. 2021 Nov 1;321(5):G500-G512. doi: 10.1152/ajpgi.00163.2021. Epub 2021 Sep 8. Am J Physiol Gastrointest Liver Physiol. 2021. PMID: 34494462 Free article.
Epicutaneous Staphylococcus aureus induces IL-36 to enhance IgE production and ensuing allergic disease.
Patrick GJ, Liu H, Alphonse MP, Dikeman DA, Youn C, Otterson JC, Wang Y, Ravipati A, Mazhar M, Denny G, Ortines RV, Zhang E, Miller RJ, Dillen CA, Liu Q, Nolan SJ, Nguyen K, Marcello L, Do DC, Wier EM, Zhang Y, Caviness G, Klimowicz AC, Mierz DV, Fine JS, Sun G, Goldbach-Mansky R, Marusina AI, Merleev AA, Maverakis E, Garza LA, Milner JD, Gao P, Ramanujam M, Raymond EL, Archer NK, Miller LS. Patrick GJ, et al. Among authors: mierz dv. J Clin Invest. 2021 Mar 1;131(5):e143334. doi: 10.1172/JCI143334. J Clin Invest. 2021. PMID: 33645549 Free PMC article.