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Page 1
A Biosafety Level 2 Mouse Model for Studying Betacoronavirus-Induced Acute Lung Damage and Systemic Manifestations.
Andrade ACDSP, Campolina-Silva GH, Queiroz-Junior CM, de Oliveira LC, Lacerda LSB, Pimenta JC, de Souza FRO, de Meira Chaves I, Passos IB, Teixeira DC, Bittencourt-Silva PG, Valadão PAC, Rossi-Oliveira L, Antunes MM, Figueiredo AFA, Wnuk NT, Temerozo JR, Ferreira AC, Cramer A, Oliveira CA, Durães-Carvalho R, Weis Arns C, Guimarães PPG, Costa GMJ, de Menezes GB, Guatimosim C, da Silva GSF, Souza TML, Barrioni BR, Pereira MM, de Sousa LP, Teixeira MM, Costa VV. Andrade ACDSP, et al. Among authors: guimaraes ppg. J Virol. 2021 Oct 27;95(22):e0127621. doi: 10.1128/JVI.01276-21. Epub 2021 Sep 8. J Virol. 2021. PMID: 34495692 Free PMC article.
Peptide fragments of bradykinin show unexpected biological activity not mediated by B1 or B2 receptors.
Souza-Silva IM, de Paula CA, Bolais-Ramos L, Santos AK, da Silva FA, de Oliveira VLS, da Rocha ID, Antunes MM, Cordeiro LPB, Teixeira VP, Scalzo Júnior SRA, Raabe AC, Guimaraes PPG, Amaral FA, Resende JM, Fontes MAP, Menezes GB, Guatimosim S, Santos RAS, Verano-Braga T. Souza-Silva IM, et al. Among authors: guimaraes ppg. Br J Pharmacol. 2022 Jun;179(12):3061-3077. doi: 10.1111/bph.15790. Epub 2022 Feb 9. Br J Pharmacol. 2022. PMID: 34978069 Free article.
Preclinical development of kinetin as a safe error-prone SARS-CoV-2 antiviral able to attenuate virus-induced inflammation.
Souza TML, Pinho VD, Setim CF, Sacramento CQ, Marcon R, Fintelman-Rodrigues N, Chaves OA, Heller M, Temerozo JR, Ferreira AC, Mattos M, Momo PB, Dias SSG, Gesto JSM, Pereira-Dutra F, Viola JPB, Queiroz-Junior CM, Guimarães LC, Chaves IM, Guimarães PPG, Costa VV, Teixeira MM, Bou-Habib DC, Bozza PT, Aguillón AR, Siqueira-Junior J, Macedo-Junior S, Andrade EL, Fadanni GP, Tolouei SEL, Potrich FB, Santos AA, Marques NF, Calixto JB, Rabi JA. Souza TML, et al. Among authors: guimaraes ppg, guimaraes lc. Nat Commun. 2023 Jan 13;14(1):199. doi: 10.1038/s41467-023-35928-z. Nat Commun. 2023. PMID: 36639383 Free PMC article.
A suitable model to investigate acute neurological consequences of coronavirus infection.
Pimenta J, Da Silva Oliveira B, Lima ALD, Machado CA, De Souza Barbosa Lacerda L, Rossi L, Queiroz-Junior CM, De Souza-Costa LP, Andrade ACSP, Gonçalves MR, Mota B, Marim FM, Aguiar RS, Guimarães PPG, Teixeira AL, Vieira LB, Guatimosim C, Teixeira MM, De Miranda AS, Costa VV. Pimenta J, et al. Among authors: guimaraes ppg. Inflamm Res. 2023 Nov;72(10-11):2073-2088. doi: 10.1007/s00011-023-01798-w. Epub 2023 Oct 14. Inflamm Res. 2023. PMID: 37837557
siRNA lipid nanoparticles for CXCL12 silencing modulate brain immune response during Zika infection.
Costa PAC, da Silva WN, Moura Prazeres PHD, Ferreira HAS, da Silva NJA, Figueiredo MM, da Silva Oliveira B, Scalzo Júnior SRA, Silva Santos FRD, Fernandes RA, Palanki R, Hamilton AG, Birbrair A, Santos VR, de Miranda AS, Mitchell MJ, Teixeira MM, Costa VV, Guimarães PPG. Costa PAC, et al. Among authors: guimaraes ppg. Biomed Pharmacother. 2024 Jan;170:115981. doi: 10.1016/j.biopha.2023.115981. Epub 2023 Dec 12. Biomed Pharmacother. 2024. PMID: 38091634 Free article.
Essential role of the CCL2-CCR2 axis in Mayaro virus-induced disease.
Santos FM, Costa VRdM, Araújo Sd, Sousa CDFd, Moreira TP, Gonçalves MR, Santos ACPMd, Ferreira HAS, Costa PAC, Barrioni BR, Bargi-Souza P, Pereira MdM, Nogueira ML, Souza DdG, Guimarães PPG, Teixeira MM, Queiroz-Junior CM, Costa VV. Santos FM, et al. Among authors: guimaraes ppg. J Virol. 2024 Jan 23;98(1):e0110223. doi: 10.1128/jvi.01102-23. Epub 2024 Jan 3. J Virol. 2024. PMID: 38169294 Free PMC article.
Nanoparticle-based DNA vaccine protects against SARS-CoV-2 variants in female preclinical models.
Guimaraes LC, Costa PAC, Scalzo Júnior SRA, Ferreira HAS, Braga ACS, de Oliveira LC, Figueiredo MM, Shepherd S, Hamilton A, Queiroz-Junior CM, da Silva WN, da Silva NJA, Rodrigues Alves MT, Santos AK, de Faria KKS, Marim FM, Fukumasu H, Birbrair A, Teixeira-Carvalho A, de Aguiar RS, Mitchell MJ, Teixeira MM, Vasconcelos Costa V, Frezard F, Guimaraes PPG. Guimaraes LC, et al. Among authors: guimaraes ppg. Nat Commun. 2024 Jan 18;15(1):590. doi: 10.1038/s41467-024-44830-1. Nat Commun. 2024. PMID: 38238326 Free PMC article.
Intranasal liposomal angiotensin-(1-7) administration reduces inflammation and viral load in the lungs during SARS-CoV-2 infection in K18-hACE2 transgenic mice.
Mendes S, Guimarães LC, Costa PAC, Fernandez CC, Figueiredo MM, Teixeira MM, Dos Santos RAS, Guimarães PPG, Frézard F. Mendes S, et al. Among authors: guimaraes ppg. Antimicrob Agents Chemother. 2024 Oct 29:e0083524. doi: 10.1128/aac.00835-24. Online ahead of print. Antimicrob Agents Chemother. 2024. PMID: 39470198 Free article.
Ionizable Lipid Nanoparticle-Mediated Delivery of Plasmid DNA in Cardiomyocytes.
Scalzo S, Santos AK, Ferreira HAS, Costa PA, Prazeres PHDM, da Silva NJA, Guimarães LC, E Silva MM, Rodrigues Alves MTR, Viana CTR, Jesus ICG, Rodrigues AP, Birbrair A, Lobo AO, Frezard F, Mitchell MJ, Guatimosim S, Guimaraes PPG. Scalzo S, et al. Among authors: guimaraes ppg, guimaraes lc. Int J Nanomedicine. 2022 Jun 30;17:2865-2881. doi: 10.2147/IJN.S366962. eCollection 2022. Int J Nanomedicine. 2022. PMID: 35795081 Free PMC article.
41 results