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Oxazoloisoindolinones with in vitro antitumor activity selectively activate a p53-pathway through potential inhibition of the p53-MDM2 interaction.
Soares J, Pereira NA, Monteiro Â, Leão M, Bessa C, Dos Santos DJ, Raimundo L, Queiroz G, Bisio A, Inga A, Pereira C, Santos MM, Saraiva L. Soares J, et al. Among authors: bisio a. Eur J Pharm Sci. 2015 Jan 23;66:138-47. doi: 10.1016/j.ejps.2014.10.006. Epub 2014 Oct 13. Eur J Pharm Sci. 2015. PMID: 25312347
Cooperative interactions between p53 and NFκB enhance cell plasticity.
Bisio A, Zámborszky J, Zaccara S, Lion M, Tebaldi T, Sharma V, Raimondi I, Alessandrini F, Ciribilli Y, Inga A. Bisio A, et al. Oncotarget. 2014 Dec 15;5(23):12111-25. doi: 10.18632/oncotarget.2545. Oncotarget. 2014. PMID: 25401416 Free PMC article.
218 results