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Local delivery of mRNA-encoded cytokines promotes antitumor immunity and tumor eradication across multiple preclinical tumor models.
Hotz C, Wagenaar TR, Gieseke F, Bangari DS, Callahan M, Cao H, Diekmann J, Diken M, Grunwitz C, Hebert A, Hsu K, Bernardo M, Karikó K, Kreiter S, Kuhn AN, Levit M, Malkova N, Masciari S, Pollard J, Qu H, Ryan S, Selmi A, Schlereth J, Singh K, Sun F, Tillmann B, Tolstykh T, Weber W, Wicke L, Witzel S, Yu Q, Zhang YA, Zheng G, Lager J, Nabel GJ, Sahin U, Wiederschain D. Hotz C, et al. Among authors: kariko k. Sci Transl Med. 2021 Sep 8;13(610):eabc7804. doi: 10.1126/scitranslmed.abc7804. Epub 2021 Sep 8. Sci Transl Med. 2021. PMID: 34516826
mRNA-based therapeutics--developing a new class of drugs.
Sahin U, Karikó K, Türeci Ö. Sahin U, et al. Among authors: kariko k. Nat Rev Drug Discov. 2014 Oct;13(10):759-80. doi: 10.1038/nrd4278. Epub 2014 Sep 19. Nat Rev Drug Discov. 2014. PMID: 25233993 Review.
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis.
Krienke C, Kolb L, Diken E, Streuber M, Kirchhoff S, Bukur T, Akilli-Öztürk Ö, Kranz LM, Berger H, Petschenka J, Diken M, Kreiter S, Yogev N, Waisman A, Karikó K, Türeci Ö, Sahin U. Krienke C, et al. Among authors: kariko k. Science. 2021 Jan 8;371(6525):145-153. doi: 10.1126/science.aay3638. Science. 2021. PMID: 33414215
Ribozyme Assays to Quantify the Capping Efficiency of In Vitro-Transcribed mRNA.
Vlatkovic I, Ludwig J, Boros G, Szabó GT, Reichert J, Buff M, Baiersdörfer M, Reinholz J, Mahiny AJ, Şahin U, Karikó K. Vlatkovic I, et al. Among authors: kariko k. Pharmaceutics. 2022 Jan 29;14(2):328. doi: 10.3390/pharmaceutics14020328. Pharmaceutics. 2022. PMID: 35214060 Free PMC article.
Developing mRNA for Therapy.
Karikó K. Karikó K. Keio J Med. 2022;71(1):31. doi: 10.2302/kjm.71-001-ABST. Keio J Med. 2022. PMID: 35342149 Free article.
mRNA: Fulfilling the Promise of Gene Therapy.
Weissman D, Karikó K. Weissman D, et al. Among authors: kariko k. Mol Ther. 2015 Sep;23(9):1416-7. doi: 10.1038/mt.2015.138. Mol Ther. 2015. PMID: 26321183 Free PMC article. No abstract available.
102 results