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Kidney toxicity of the BRAF-kinase inhibitor vemurafenib is driven by off-target ferrochelatase inhibition.
Bai Y, Kim JY, Bisunke B, Jayne LA, Silvaroli JA, Balzer MS, Gandhi M, Huang KM, Sander V, Prosek J, Cianciolo RE, Baker SD, Sparreboom A, Jhaveri KD, Susztak K, Bajwa A, Pabla NS. Bai Y, et al. Among authors: sander v. Kidney Int. 2021 Dec;100(6):1214-1226. doi: 10.1016/j.kint.2021.08.022. Epub 2021 Sep 15. Kidney Int. 2021. PMID: 34534550 Free PMC article.
Synthesis, Structure-Activity Relationship Study, Bioactivity, and Nephrotoxicity Evaluation of the Proposed Structure of the Cyclic Lipodepsipeptide Brevicidine B.
Palpal-Latoc D, Horsfall AJ, Cameron AJ, Campbell G, Ferguson SA, Cook GM, Sander V, Davidson AJ, Harris PWR, Brimble MA. Palpal-Latoc D, et al. Among authors: sander v. J Nat Prod. 2024 Apr 26;87(4):764-773. doi: 10.1021/acs.jnatprod.3c00876. Epub 2024 Feb 29. J Nat Prod. 2024. PMID: 38423998
Synthesis, Antibacterial Activity, and Nephrotoxicity of Polymyxin B Analogues Modified at Leu-7, d-Phe-6, and the N-Terminus Enabled by S-Lipidation.
Harris PWR, Siow A, Yang SH, Wadsworth AD, Tan L, Hermant Y, Mao Y, An C, Hanna CC, Cameron AJ, Allison JR, Chakraborty A, Ferguson SA, Mros S, Hards K, Cook GM, Williamson DA, Carter GP, Chan STS, Painter GA, Sander V, Davidson AJ, Brimble MA. Harris PWR, et al. Among authors: sander v. ACS Infect Dis. 2022 Dec 9;8(12):2413-2429. doi: 10.1021/acsinfecdis.1c00347. Epub 2022 Nov 22. ACS Infect Dis. 2022. PMID: 36413173
Evaluation of cisplatin-induced injury in human kidney organoids.
Digby JLM, Vanichapol T, Przepiorski A, Davidson AJ, Sander V. Digby JLM, et al. Among authors: sander v. Am J Physiol Renal Physiol. 2020 Apr 1;318(4):F971-F978. doi: 10.1152/ajprenal.00597.2019. Epub 2020 Mar 9. Am J Physiol Renal Physiol. 2020. PMID: 32150447 Free PMC article.
Kidney injury and regeneration in zebrafish.
Sander V, Davidson AJ. Sander V, et al. Semin Nephrol. 2014 Jul;34(4):437-44. doi: 10.1016/j.semnephrol.2014.06.010. Epub 2014 Jun 13. Semin Nephrol. 2014. PMID: 25217272 Review.
Validation of HDAC8 Inhibitors as Drug Discovery Starting Points to Treat Acute Kidney Injury.
Long K, Vaughn Z, McDaniels MD, Joyasawal S, Przepiorski A, Parasky E, Sander V, Close D, Johnston PA, Davidson AJ, de Caestecker M, Hukriede NA, Huryn DM. Long K, et al. Among authors: sander v. ACS Pharmacol Transl Sci. 2022 Mar 16;5(4):207-215. doi: 10.1021/acsptsci.1c00243. eCollection 2022 Apr 8. ACS Pharmacol Transl Sci. 2022. PMID: 35434532 Free PMC article.
105 results