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802 results

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Page 1
MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I.
Brägelmann J, Lorenz C, Borchmann S, Nishii K, Wegner J, Meder L, Ostendorp J, Ast DF, Heimsoeth A, Nakasuka T, Hirabae A, Okawa S, Dammert MA, Plenker D, Klein S, Lohneis P, Gu J, Godfrey LK, Forster J, Trajkovic-Arsic M, Zillinger T, Haarmann M, Quaas A, Lennartz S, Schmiel M, D'Rozario J, Thomas ES, Li H, Schmitt CA, George J, Thomas RK, von Karstedt S, Hartmann G, Büttner R, Ullrich RT, Siveke JT, Ohashi K, Schlee M, Sos ML. Brägelmann J, et al. Among authors: hartmann g. Nat Commun. 2021 Sep 17;12(1):5505. doi: 10.1038/s41467-021-25728-8. Nat Commun. 2021. PMID: 34535668 Free PMC article.
siRNA and isRNA: two edges of one sword.
Schlee M, Hornung V, Hartmann G. Schlee M, et al. Among authors: hartmann g. Mol Ther. 2006 Oct;14(4):463-70. doi: 10.1016/j.ymthe.2006.06.001. Epub 2006 Jul 31. Mol Ther. 2006. PMID: 16877044 Free article. Review.
5'-Triphosphate RNA is the ligand for RIG-I.
Hornung V, Ellegast J, Kim S, Brzózka K, Jung A, Kato H, Poeck H, Akira S, Conzelmann KK, Schlee M, Endres S, Hartmann G. Hornung V, et al. Among authors: hartmann g. Science. 2006 Nov 10;314(5801):994-7. doi: 10.1126/science.1132505. Epub 2006 Oct 12. Science. 2006. PMID: 17038590
RNA recognition via TLR7 and TLR8.
Hornung V, Barchet W, Schlee M, Hartmann G. Hornung V, et al. Among authors: hartmann g. Handb Exp Pharmacol. 2008;(183):71-86. doi: 10.1007/978-3-540-72167-3_4. Handb Exp Pharmacol. 2008. PMID: 18071655 Review.
5'-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma.
Poeck H, Besch R, Maihoefer C, Renn M, Tormo D, Morskaya SS, Kirschnek S, Gaffal E, Landsberg J, Hellmuth J, Schmidt A, Anz D, Bscheider M, Schwerd T, Berking C, Bourquin C, Kalinke U, Kremmer E, Kato H, Akira S, Meyers R, Häcker G, Neuenhahn M, Busch D, Ruland J, Rothenfusser S, Prinz M, Hornung V, Endres S, Tüting T, Hartmann G. Poeck H, et al. Among authors: hartmann g. Nat Med. 2008 Nov;14(11):1256-63. doi: 10.1038/nm.1887. Epub 2008 Nov 2. Nat Med. 2008. PMID: 18978796
Approaching the RNA ligand for RIG-I?
Schlee M, Hartmann E, Coch C, Wimmenauer V, Janke M, Barchet W, Hartmann G. Schlee M, et al. Among authors: hartmann g, hartmann e. Immunol Rev. 2009 Jan;227(1):66-74. doi: 10.1111/j.1600-065X.2008.00724.x. Immunol Rev. 2009. PMID: 19120476 Review.
Selection of molecular structure and delivery of RNA oligonucleotides to activate TLR7 versus TLR8 and to induce high amounts of IL-12p70 in primary human monocytes.
Ablasser A, Poeck H, Anz D, Berger M, Schlee M, Kim S, Bourquin C, Goutagny N, Jiang Z, Fitzgerald KA, Rothenfusser S, Endres S, Hartmann G, Hornung V. Ablasser A, et al. Among authors: hartmann g. J Immunol. 2009 Jun 1;182(11):6824-33. doi: 10.4049/jimmunol.0803001. J Immunol. 2009. PMID: 19454678
802 results