Chen SRW - Search Results

1

Human RyR2 (Ryanodine Receptor 2) Loss-of-Function Mutations: Clinical Phenotypes and In Vitro Characterization.

Li Y, Wei J, Guo W, Sun B, Estillore JP, Wang R, Yoruk A, Roston TM, Sanatani S, Wilde AAM, Gollob MH, Roberts JD, Tseng ZH, Jensen HK, Chen SRW. Li Y, et al. Among authors: chen srw. Circ Arrhythm Electrophysiol. 2021 Sep;14(9):e010013. doi: 10.1161/CIRCEP.121.010013. Epub 2021 Sep 1. Circ Arrhythm Electrophysiol. 2021. PMID: 34546788

2

Enhanced basal activity of a cardiac Ca2+ release channel (ryanodine receptor) mutant associated with ventricular tachycardia and sudden death.

Jiang D, Xiao B, Zhang L, Chen SR. Jiang D, et al. Circ Res. 2002 Aug 9;91(3):218-25. doi: 10.1161/01.res.0000028455.36940.5e. Circ Res. 2002. PMID: 12169647

3

Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).

Xiao B, Masumiya H, Jiang D, Wang R, Sei Y, Zhang L, Murayama T, Ogawa Y, Lai FA, Wagenknecht T, Chen SR. Xiao B, et al. J Biol Chem. 2002 Nov 1;277(44):41778-85. doi: 10.1074/jbc.M208210200. Epub 2002 Sep 3. J Biol Chem. 2002. PMID: 12213830 Free article.

4

Localization of the 12.6-kDa FK506-binding protein (FKBP12.6) binding site to the NH2-terminal domain of the cardiac Ca2+ release channel (ryanodine receptor).

Masumiya H, Wang R, Zhang J, Xiao B, Chen SR. Masumiya H, et al. J Biol Chem. 2003 Feb 7;278(6):3786-92. doi: 10.1074/jbc.M210962200. Epub 2002 Nov 22. J Biol Chem. 2003. PMID: 12446682 Free article.

5

Three-dimensional localization of divergent region 3 of the ryanodine receptor to the clamp-shaped structures adjacent to the FKBP binding sites.

Zhang J, Liu Z, Masumiya H, Wang R, Jiang D, Li F, Wagenknecht T, Chen SR. Zhang J, et al. J Biol Chem. 2003 Apr 18;278(16):14211-8. doi: 10.1074/jbc.M213164200. Epub 2003 Feb 7. J Biol Chem. 2003. PMID: 12576471 Free article.

6

Residue Gln4863 within a predicted transmembrane sequence of the Ca2+ release channel (ryanodine receptor) is critical for ryanodine interaction.

Wang R, Zhang L, Bolstad J, Diao N, Brown C, Ruest L, Welch W, Williams AJ, Chen SR. Wang R, et al. J Biol Chem. 2003 Dec 19;278(51):51557-65. doi: 10.1074/jbc.M306788200. Epub 2003 Oct 13. J Biol Chem. 2003. PMID: 14557272 Free article.

7

The predicted TM10 transmembrane sequence of the cardiac Ca2+ release channel (ryanodine receptor) is crucial for channel activation and gating.

Wang R, Bolstad J, Kong H, Zhang L, Brown C, Chen SR. Wang R, et al. J Biol Chem. 2004 Jan 30;279(5):3635-42. doi: 10.1074/jbc.M311367200. Epub 2003 Oct 30. J Biol Chem. 2004. PMID: 14593104 Free article.

8

Protein kinase A phosphorylation at serine-2808 of the cardiac Ca2+-release channel (ryanodine receptor) does not dissociate 12.6-kDa FK506-binding protein (FKBP12.6).

Xiao B, Sutherland C, Walsh MP, Chen SR. Xiao B, et al. Circ Res. 2004 Mar 5;94(4):487-95. doi: 10.1161/01.RES.0000115945.89741.22. Epub 2004 Jan 8. Circ Res. 2004. PMID: 14715536

9

RyR2 mutations linked to ventricular tachycardia and sudden death reduce the threshold for store-overload-induced Ca2+ release (SOICR).

Jiang D, Xiao B, Yang D, Wang R, Choi P, Zhang L, Cheng H, Chen SR. Jiang D, et al. Proc Natl Acad Sci U S A. 2004 Aug 31;101(35):13062-7. doi: 10.1073/pnas.0402388101. Epub 2004 Aug 20. Proc Natl Acad Sci U S A. 2004. PMID: 15322274 Free PMC article.

10

Characterization of a novel PKA phosphorylation site, serine-2030, reveals no PKA hyperphosphorylation of the cardiac ryanodine receptor in canine heart failure.

Xiao B, Jiang MT, Zhao M, Yang D, Sutherland C, Lai FA, Walsh MP, Warltier DC, Cheng H, Chen SR. Xiao B, et al. Circ Res. 2005 Apr 29;96(8):847-55. doi: 10.1161/01.RES.0000163276.26083.e8. Epub 2005 Mar 24. Circ Res. 2005. PMID: 15790957

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