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Rare and de novo variants in 827 congenital diaphragmatic hernia probands implicate LONP1 as candidate risk gene.
Qiao L, Xu L, Yu L, Wynn J, Hernan R, Zhou X, Farkouh-Karoleski C, Krishnan US, Khlevner J, De A, Zygmunt A, Crombleholme T, Lim FY, Needelman H, Cusick RA, Mychaliska GB, Warner BW, Wagner AJ, Danko ME, Chung D, Potoka D, Kosiński P, McCulley DJ, Elfiky M, Azarow K, Fialkowski E, Schindel D, Soffer SZ, Lyon JB, Zalieckas JM, Vardarajan BN, Aspelund G, Duron VP, High FA, Sun X, Donahoe PK, Shen Y, Chung WK. Qiao L, et al. Among authors: xu l. Am J Hum Genet. 2021 Oct 7;108(10):1964-1980. doi: 10.1016/j.ajhg.2021.08.011. Epub 2021 Sep 20. Am J Hum Genet. 2021. PMID: 34547244 Free PMC article.
Airway Microfold Cells Emerge in the Post-Influenza Lung.
Barr J, Xu L, Li R, Verheyden J, Sun X. Barr J, et al. Among authors: xu l. Am J Respir Cell Mol Biol. 2024 Apr;70(4):322-325. doi: 10.1165/rcmb.2023-0351LE. Am J Respir Cell Mol Biol. 2024. PMID: 38127584 No abstract available.
Context-dependent roles of mitochondrial LONP1 in orchestrating the balance between airway progenitor versus progeny cells.
Xu L, Tan C, Barr J, Talaba N, Verheyden J, Chin JS, Gaboyan S, Kasaraneni N, Elgamal RM, Gaulton KJ, Lin G, Afshar K, Golts E, Meier A, Alexander LEC, Borok Z, Shen Y, Chung WK, McCulley DJ, Sun X. Xu L, et al. Cell Stem Cell. 2024 Oct 3;31(10):1465-1483.e6. doi: 10.1016/j.stem.2024.08.001. Epub 2024 Aug 23. Cell Stem Cell. 2024. PMID: 39181129
Brainstem Dbh+ neurons control allergen-induced airway hyperreactivity.
Su Y, Xu J, Zhu Z, Chin J, Xu L, Yu H, Nudell V, Dash B, Moya EA, Ye L, Nimmerjahn A, Sun X. Su Y, et al. Among authors: xu l, xu j. Nature. 2024 Jul;631(8021):601-609. doi: 10.1038/s41586-024-07608-5. Epub 2024 Jul 10. Nature. 2024. PMID: 38987587 Free PMC article.
Excess neuropeptides in lung signal through endothelial cells to impair gas exchange.
Xu J, Xu L, Sui P, Chen J, Moya EA, Hume P, Janssen WJ, Duran JM, Thistlethwaite P, Carlin A, Gulleman P, Banaschewski B, Goldy MK, Yuan JX, Malhotra A, Pryhuber G, Crotty-Alexander L, Deutsch G, Young LR, Sun X. Xu J, et al. Among authors: xu l. Dev Cell. 2022 Apr 11;57(7):839-853.e6. doi: 10.1016/j.devcel.2022.02.023. Epub 2022 Mar 17. Dev Cell. 2022. PMID: 35303432 Free PMC article.
Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 severity.
Inde Z, Croker BA, Yapp C, Joshi GN, Spetz J, Fraser C, Qin X, Xu L, Deskin B, Ghelfi E, Webb G, Carlin AF, Zhu YP, Leibel SL, Garretson AF, Clark AE, Duran JM, Pretorius V, Crotty-Alexander LE, Li C, Lee JC, Sodhi C, Hackam DJ, Sun X, Hata AN, Kobzik L, Miller J, Park JA, Brownfield D, Jia H, Sarosiek KA. Inde Z, et al. Among authors: xu l. Sci Adv. 2021 Aug 18;7(34):eabf8609. doi: 10.1126/sciadv.abf8609. Print 2021 Aug. Sci Adv. 2021. PMID: 34407940 Free PMC article.
PI3Kγ inhibition circumvents inflammation and vascular leak in SARS-CoV-2 and other infections.
Shepard RM, Ghebremedhin A, Pratumchai I, Robinson SR, Betts C, Hu J, Sasik R, Fisch KM, Zak J, Chen H, Paradise M, Rivera J, Amjad M, Uchiyama S, Seo H, Campos AD, Dayao DA, Tzipori S, Piedra-Mora C, Das S, Hasteh F, Russo H, Sun X, Xu L, E Alexander LC, Duran JM, Odish M, Pretorius V, Kirchberger NC, Chin SM, Von Schalscha T, Cheresh D, Morrey JD, Alargova R, O'Connell B, Martinot TA, Patel SP, Nizet V, Martinot AJ, Coussens LM, Teijaro JR, Varner JA. Shepard RM, et al. Among authors: xu l. Sci Transl Med. 2024 Jul 3;16(754):eadi6887. doi: 10.1126/scitranslmed.adi6887. Epub 2024 Jul 3. Sci Transl Med. 2024. PMID: 38959328 Free PMC article.
Increased Peripheral Blood Neutrophil Activation Phenotypes and Neutrophil Extracellular Trap Formation in Critically Ill Coronavirus Disease 2019 (COVID-19) Patients: A Case Series and Review of the Literature.
Masso-Silva JA, Moshensky A, Lam MTY, Odish MF, Patel A, Xu L, Hansen E, Trescott S, Nguyen C, Kim R, Perofsky K, Perera S, Ma L, Pham J, Rolfsen M, Olay J, Shin J, Dan JM, Abbott RK, Ramirez S, Alexander TH, Lin GY, Fuentes AL, Advani I, Gunge D, Pretorius V, Malhotra A, Sun X, Duran J, Hepokoski M, Crotty S, Coufal NG, Meier A, Crotty Alexander LE. Masso-Silva JA, et al. Among authors: xu l. Clin Infect Dis. 2022 Feb 11;74(3):479-489. doi: 10.1093/cid/ciab437. Clin Infect Dis. 2022. PMID: 33988226 Free PMC article. Review.
Correction to: Increased Peripheral Blood Neutrophil Activation Phenotypes and Neutrophil Extracellular Trap Formation in Critically Ill Coronavirus Disease 2019 Patients: A Case Series and Review of the Literature.
Masso-Silva JA, Moshensky A, Lam MTY, Odish M, Patel A, Xu L, Hansen E, Trescott S, Nguyen C, Kim R, Perofsky K, Perera S, Ma L, Pham J, Rolfsen M, Olay J, Shin J, Dan JM, Abbott R, Ramirez S, Alexander TH, Lin GY, Fuentes AL, Advani I, Gunge D, Pretorius V, Malhotra A, Sun X, Duran J, Hepokoski M, Crotty S, Coufal NG, Meier A, Crotty Alexander LE. Masso-Silva JA, et al. Among authors: xu l. Clin Infect Dis. 2022 May 30;74(10):1889-1890. doi: 10.1093/cid/ciac216. Clin Infect Dis. 2022. PMID: 35416961 Free PMC article. No abstract available.
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