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A20 deficiency in myeloid cells protects mice from diet-induced obesity and insulin resistance due to increased fatty acid metabolism.
Catrysse L, Maes B, Mehrotra P, Martens A, Hoste E, Martens L, Maueröder C, Remmerie A, Bujko A, Slowicka K, Sze M, Vikkula H, Ghesquière B, Scott CL, Saeys Y, van de Sluis B, Ravichandran K, Janssens S, van Loo G. Catrysse L, et al. Cell Rep. 2021 Sep 21;36(12):109748. doi: 10.1016/j.celrep.2021.109748. Cell Rep. 2021. PMID: 34551300 Free article.
A20 in inflammation and autoimmunity.
Catrysse L, Vereecke L, Beyaert R, van Loo G. Catrysse L, et al. Trends Immunol. 2014 Jan;35(1):22-31. doi: 10.1016/j.it.2013.10.005. Epub 2013 Nov 15. Trends Immunol. 2014. PMID: 24246475 Review.
A20 Inhibits β-Cell Apoptosis by Multiple Mechanisms and Predicts Residual β-Cell Function in Type 1 Diabetes.
Fukaya M, Brorsson CA, Meyerovich K, Catrysse L, Delaroche D, Vanzela EC, Ortis F, Beyaert R, Nielsen LB, Andersen ML, Mortensen HB, Pociot F, van Loo G, Størling J, Cardozo AK. Fukaya M, et al. Among authors: catrysse l. Mol Endocrinol. 2016 Jan;30(1):48-61. doi: 10.1210/me.2015-1176. Epub 2015 Dec 10. Mol Endocrinol. 2016. PMID: 26652732 Free PMC article.
A20 inhibition of STAT1 expression in myeloid cells: a novel endogenous regulatory mechanism preventing development of enthesitis.
De Wilde K, Martens A, Lambrecht S, Jacques P, Drennan MB, Debusschere K, Govindarajan S, Coudenys J, Verheugen E, Windels F, Catrysse L, Lories R, McGonagle D, Beyaert R, van Loo G, Elewaut D. De Wilde K, et al. Among authors: catrysse l. Ann Rheum Dis. 2017 Mar;76(3):585-592. doi: 10.1136/annrheumdis-2016-209454. Epub 2016 Aug 22. Ann Rheum Dis. 2017. PMID: 27551052
Epithelial HMGB1 Delays Skin Wound Healing and Drives Tumor Initiation by Priming Neutrophils for NET Formation.
Hoste E, Maueröder C, van Hove L, Catrysse L, Vikkula HK, Sze M, Maes B, Karjosukarso D, Martens L, Gonçalves A, Parthoens E, Roelandt R, Declercq W, Fuentes I, Palisson F, Gonzalez S, Salas-Alanis JC, Boon L, Huebener P, Mulder KW, Ravichandran K, Saeys Y, Schwabe RF, van Loo G. Hoste E, et al. Among authors: catrysse l. Cell Rep. 2019 Nov 26;29(9):2689-2701.e4. doi: 10.1016/j.celrep.2019.10.104. Cell Rep. 2019. PMID: 31775038 Free article.
Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities.
Martens A, Priem D, Hoste E, Vetters J, Rennen S, Catrysse L, Voet S, Deelen L, Sze M, Vikkula H, Slowicka K, Hochepied T, Iliaki K, Wullaert A, Janssens S, Lamkanfi M, Beyaert R, Armaka M, Bertrand MJM, van Loo G. Martens A, et al. Among authors: catrysse l. Nat Immunol. 2020 Apr;21(4):381-387. doi: 10.1038/s41590-020-0621-9. Epub 2020 Mar 16. Nat Immunol. 2020. PMID: 32205881
20 results