Liu Q - Search Results

1

Structures of full-length glycoprotein hormone receptor signalling complexes.

Duan J, Xu P, Cheng X, Mao C, Croll T, He X, Shi J, Luan X, Yin W, You E, Liu Q, Zhang S, Jiang H, Zhang Y, Jiang Y, Xu HE. Duan J, et al. Among authors: liu q. Nature. 2021 Oct;598(7882):688-692. doi: 10.1038/s41586-021-03924-2. Epub 2021 Sep 22. Nature. 2021. PMID: 34552239

2

Structure-based design of a hyperthermostable AgUricase for hyperuricemia and gout therapy.

Shi Y, Wang T, Zhou XE, Liu QF, Jiang Y, Xu HE. Shi Y, et al. Acta Pharmacol Sin. 2019 Oct;40(10):1364-1372. doi: 10.1038/s41401-019-0269-x. Epub 2019 Jun 28. Acta Pharmacol Sin. 2019. PMID: 31253939 Free PMC article.

3

Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design.

Wang Y, Dai Y, Wu X, Li F, Liu B, Li C, Liu Q, Zhou Y, Wang B, Zhu M, Cui R, Tan X, Xiong Z, Liu J, Tan M, Xu Y, Geng M, Jiang H, Liu H, Ai J, Zheng M. Wang Y, et al. Among authors: liu j, liu h, liu b, liu q. J Med Chem. 2019 Aug 22;62(16):7473-7488. doi: 10.1021/acs.jmedchem.9b00510. Epub 2019 Aug 9. J Med Chem. 2019. PMID: 31335138

4

Cryo-EM structure of an activated VIP1 receptor-G protein complex revealed by a NanoBiT tethering strategy.

Duan J, Shen DD, Zhou XE, Bi P, Liu QF, Tan YX, Zhuang YW, Zhang HB, Xu PY, Huang SJ, Ma SS, He XH, Melcher K, Zhang Y, Xu HE, Jiang Y. Duan J, et al. Nat Commun. 2020 Aug 17;11(1):4121. doi: 10.1038/s41467-020-17933-8. Nat Commun. 2020. PMID: 32807782 Free PMC article.

5

Kinetics-Driven Drug Design Strategy for Next-Generation Acetylcholinesterase Inhibitors to Clinical Candidate.

Zhou Y, Fu Y, Yin W, Li J, Wang W, Bai F, Xu S, Gong Q, Peng T, Hong Y, Zhang D, Zhang D, Liu Q, Xu Y, Xu HE, Zhang H, Jiang H, Liu H. Zhou Y, et al. Among authors: liu h, liu q. J Med Chem. 2021 Feb 25;64(4):1844-1855. doi: 10.1021/acs.jmedchem.0c01863. Epub 2021 Feb 11. J Med Chem. 2021. PMID: 33570950

6

Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor.

Liu Q, Yang D, Zhuang Y, Croll TI, Cai X, Dai A, He X, Duan J, Yin W, Ye C, Zhou F, Wu B, Zhao Q, Xu HE, Wang MW, Jiang Y. Liu Q, et al. Nat Chem Biol. 2021 Dec;17(12):1238-1244. doi: 10.1038/s41589-021-00841-3. Epub 2021 Sep 23. Nat Chem Biol. 2021. PMID: 34556862 Free PMC article.

7

Molecular basis for allosteric agonism and G protein subtype selectivity of galanin receptors.

Duan J, Shen DD, Zhao T, Guo S, He X, Yin W, Xu P, Ji Y, Chen LN, Liu J, Zhang H, Liu Q, Shi Y, Cheng X, Jiang H, Eric Xu H, Zhang Y, Xie X, Jiang Y. Duan J, et al. Among authors: liu j, liu q. Nat Commun. 2022 Mar 15;13(1):1364. doi: 10.1038/s41467-022-29072-3. Nat Commun. 2022. PMID: 35292680 Free PMC article.

8

Insights into divalent cation regulation and G₁₃-coupling of orphan receptor GPR35.

Duan J, Liu Q, Yuan Q, Ji Y, Zhu S, Tan Y, He X, Xu Y, Shi J, Cheng X, Jiang H, Eric Xu H, Jiang Y. Duan J, et al. Among authors: liu q. Cell Discov. 2022 Dec 21;8(1):135. doi: 10.1038/s41421-022-00499-8. Cell Discov. 2022. PMID: 36543774 Free PMC article.

9

Free energy landscape for the binding process of Huperzine A to acetylcholinesterase.

Bai F, Xu Y, Chen J, Liu Q, Gu J, Wang X, Ma J, Li H, Onuchic JN, Jiang H. Bai F, et al. Among authors: liu q. Proc Natl Acad Sci U S A. 2013 Mar 12;110(11):4273-8. doi: 10.1073/pnas.1301814110. Epub 2013 Feb 25. Proc Natl Acad Sci U S A. 2013. PMID: 23440190 Free PMC article.

10

Structural and Thermodynamic Characterization of Protein-Ligand Interactions Formed between Lipoprotein-Associated Phospholipase A2 and Inhibitors.

Liu Q, Chen X, Chen W, Yuan X, Su H, Shen J, Xu Y. Liu Q, et al. J Med Chem. 2016 May 26;59(10):5115-20. doi: 10.1021/acs.jmedchem.6b00282. Epub 2016 Apr 26. J Med Chem. 2016. PMID: 27078579

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