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ERα is an RNA-binding protein sustaining tumor cell survival and drug resistance.
Xu Y, Huangyang P, Wang Y, Xue L, Devericks E, Nguyen HG, Yu X, Oses-Prieto JA, Burlingame AL, Miglani S, Goodarzi H, Ruggero D. Xu Y, et al. Among authors: goodarzi h. Cell. 2021 Sep 30;184(20):5215-5229.e17. doi: 10.1016/j.cell.2021.08.036. Epub 2021 Sep 23. Cell. 2021. PMID: 34559986 Free PMC article.
Nuclear TARBP2 Drives Oncogenic Dysregulation of RNA Splicing and Decay.
Fish L, Navickas A, Culbertson B, Xu Y, Nguyen HCB, Zhang S, Hochman M, Okimoto R, Dill BD, Molina H, Najafabadi HS, Alarcón C, Ruggero D, Goodarzi H. Fish L, et al. Among authors: goodarzi h. Mol Cell. 2019 Sep 5;75(5):967-981.e9. doi: 10.1016/j.molcel.2019.06.001. Epub 2019 Jul 9. Mol Cell. 2019. PMID: 31300274 Free PMC article.
The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles.
Leidal AM, Huang HH, Marsh T, Solvik T, Zhang D, Ye J, Kai F, Goldsmith J, Liu JY, Huang YH, Monkkonen T, Vlahakis A, Huang EJ, Goodarzi H, Yu L, Wiita AP, Debnath J. Leidal AM, et al. Among authors: goodarzi h. Nat Cell Biol. 2020 Feb;22(2):187-199. doi: 10.1038/s41556-019-0450-y. Epub 2020 Jan 13. Nat Cell Biol. 2020. PMID: 31932738 Free PMC article.
An mRNA processing pathway suppresses metastasis by governing translational control from the nucleus.
Navickas A, Asgharian H, Winkler J, Fish L, Garcia K, Markett D, Dodel M, Culbertson B, Miglani S, Joshi T, Yin K, Nguyen P, Zhang S, Stevers N, Hwang HW, Mardakheh F, Goga A, Goodarzi H. Navickas A, et al. Among authors: goodarzi h. Nat Cell Biol. 2023 Jun;25(6):892-903. doi: 10.1038/s41556-023-01141-9. Epub 2023 May 8. Nat Cell Biol. 2023. PMID: 37156909 Free PMC article.
Direct transposition of native DNA for sensitive multimodal single-molecule sequencing.
Nanda AS, Wu K, Irkliyenko I, Woo B, Ostrowski MS, Clugston AS, Sayles LC, Xu L, Satpathy AT, Nguyen HG, Alejandro Sweet-Cordero E, Goodarzi H, Kasinathan S, Ramani V. Nanda AS, et al. Among authors: goodarzi h. Nat Genet. 2024 Jun;56(6):1300-1309. doi: 10.1038/s41588-024-01748-0. Epub 2024 May 9. Nat Genet. 2024. PMID: 38724748 Free PMC article.
Systematic identification of post-transcriptional regulatory modules.
Khoroshkin M, Buyan A, Dodel M, Navickas A, Yu J, Trejo F, Doty A, Baratam R, Zhou S, Lee SB, Joshi T, Garcia K, Choi B, Miglani S, Subramanyam V, Modi H, Carpenter C, Markett D, Corces MR, Mardakheh FK, Kulakovskiy IV, Goodarzi H. Khoroshkin M, et al. Among authors: goodarzi h. Nat Commun. 2024 Sep 9;15(1):7872. doi: 10.1038/s41467-024-52215-7. Nat Commun. 2024. PMID: 39251607 Free PMC article.
Functional screen for mediators of onco-mRNA translation specificity.
Kovalski JR, Sarioglu G, Subramanyam V, Hernandez G, Rademaker G, Oses-Prieto JA, Slota M, Mohan N, Yiakis K, Liu I, Wen KW, Kim GE, Miglani S, Burlingame AL, Goodarzi H, Perera RM, Ruggero D. Kovalski JR, et al. Among authors: goodarzi h. bioRxiv [Preprint]. 2024 Oct 11:2024.10.10.617637. doi: 10.1101/2024.10.10.617637. bioRxiv. 2024. PMID: 39416102 Free PMC article. Preprint.
190 results