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Page 1
A prenylated dsRNA sensor protects against severe COVID-19.
Wickenhagen A, Sugrue E, Lytras S, Kuchi S, Noerenberg M, Turnbull ML, Loney C, Herder V, Allan J, Jarmson I, Cameron-Ruiz N, Varjak M, Pinto RM, Lee JY, Iselin L, Palmalux N, Stewart DG, Swingler S, Greenwood EJD, Crozier TWM, Gu Q, Davies EL, Clohisey S, Wang B, Trindade Maranhão Costa F, Freire Santana M, de Lima Ferreira LC, Murphy L, Fawkes A, Meynert A, Grimes G; ISARIC4C Investigators; Da Silva Filho JL, Marti M, Hughes J, Stanton RJ, Wang ECY, Ho A, Davis I, Jarrett RF, Castello A, Robertson DL, Semple MG, Openshaw PJM, Palmarini M, Lehner PJ, Baillie JK, Rihn SJ, Wilson SJ. Wickenhagen A, et al. Among authors: wang ecy. Science. 2021 Oct 29;374(6567):eabj3624. doi: 10.1126/science.abj3624. Epub 2021 Oct 29. Science. 2021. PMID: 34581622 Free PMC article.
Two novel human cytomegalovirus NK cell evasion functions target MICA for lysosomal degradation.
Fielding CA, Aicheler R, Stanton RJ, Wang EC, Han S, Seirafian S, Davies J, McSharry BP, Weekes MP, Antrobus PR, Prod'homme V, Blanchet FP, Sugrue D, Cuff S, Roberts D, Davison AJ, Lehner PJ, Wilkinson GW, Tomasec P. Fielding CA, et al. PLoS Pathog. 2014 May 1;10(5):e1004058. doi: 10.1371/journal.ppat.1004058. eCollection 2014 May. PLoS Pathog. 2014. PMID: 24787765 Free PMC article.
HCMV pUL135 remodels the actin cytoskeleton to impair immune recognition of infected cells.
Stanton RJ, Prod'homme V, Purbhoo MA, Moore M, Aicheler RJ, Heinzmann M, Bailer SM, Haas J, Antrobus R, Weekes MP, Lehner PJ, Vojtesek B, Miners KL, Man S, Wilkie GS, Davison AJ, Wang ECY, Tomasec P, Wilkinson GWG. Stanton RJ, et al. Among authors: wang ecy. Cell Host Microbe. 2014 Aug 13;16(2):201-214. doi: 10.1016/j.chom.2014.07.005. Cell Host Microbe. 2014. PMID: 25121749 Free PMC article.
Suppression of costimulation by human cytomegalovirus promotes evasion of cellular immune defenses.
Wang ECY, Pjechova M, Nightingale K, Vlahava VM, Patel M, Ruckova E, Forbes SK, Nobre L, Antrobus R, Roberts D, Fielding CA, Seirafian S, Davies J, Murrell I, Lau B, Wilkie GS, Suárez NM, Stanton RJ, Vojtesek B, Davison A, Lehner PJ, Weekes MP, Wilkinson GWG, Tomasec P. Wang ECY, et al. Proc Natl Acad Sci U S A. 2018 May 8;115(19):4998-5003. doi: 10.1073/pnas.1720950115. Epub 2018 Apr 24. Proc Natl Acad Sci U S A. 2018. PMID: 29691324 Free PMC article.
High-Definition Analysis of Host Protein Stability during Human Cytomegalovirus Infection Reveals Antiviral Factors and Viral Evasion Mechanisms.
Nightingale K, Lin KM, Ravenhill BJ, Davies C, Nobre L, Fielding CA, Ruckova E, Fletcher-Etherington A, Soday L, Nichols H, Sugrue D, Wang ECY, Moreno P, Umrania Y, Huttlin EL, Antrobus R, Davison AJ, Wilkinson GWG, Stanton RJ, Tomasec P, Weekes MP. Nightingale K, et al. Among authors: wang ecy. Cell Host Microbe. 2018 Sep 12;24(3):447-460.e11. doi: 10.1016/j.chom.2018.07.011. Epub 2018 Aug 16. Cell Host Microbe. 2018. PMID: 30122656 Free PMC article.
Human Cytomegalovirus Long Non-coding RNA1.2 Suppresses Extracellular Release of the Pro-inflammatory Cytokine IL-6 by Blocking NF-κB Activation.
Lau B, Kerr K, Gu Q, Nightingale K, Antrobus R, Suárez NM, Stanton RJ, Wang ECY, Weekes MP, Davison AJ. Lau B, et al. Among authors: wang ecy. Front Cell Infect Microbiol. 2020 Jul 22;10:361. doi: 10.3389/fcimb.2020.00361. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 32793512 Free PMC article.
89 results