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Chemotherapy and mismatch repair deficiency cooperate to fuel TP53 mutagenesis and ALL relapse.
Yang F, Brady SW, Tang C, Sun H, Du L, Barz MJ, Ma X, Chen Y, Fang H, Li X, Kolekar P, Pathak O, Cai J, Ding L, Wang T, von Stackelberg A, Shen S, Eckert C, Klco JM, Chen H, Duan C, Liu Y, Li H, Li B, Kirschner-Schwabe R, Zhang J, Zhou BS. Yang F, et al. Nat Cancer. 2021 Aug;2(8):819-834. doi: 10.1038/s43018-021-00230-8. Epub 2021 Jul 22. Nat Cancer. 2021. PMID: 35122027
Therapy-induced mutations drive the genomic landscape of relapsed acute lymphoblastic leukemia.
Li B, Brady SW, Ma X, Shen S, Zhang Y, Li Y, Szlachta K, Dong L, Liu Y, Yang F, Wang N, Flasch DA, Myers MA, Mulder HL, Ding L, Liu Y, Tian L, Hagiwara K, Xu K, Zhou X, Sioson E, Wang T, Yang L, Zhao J, Zhang H, Shao Y, Sun H, Sun L, Cai J, Sun HY, Lin TN, Du L, Li H, Rusch M, Edmonson MN, Easton J, Zhu X, Zhang J, Cheng C, Raphael BJ, Tang J, Downing JR, Alexandrov LB, Zhou BS, Pui CH, Yang JJ, Zhang J. Li B, et al. Among authors: yang f, yang l, yang jj. Blood. 2020 Jan 2;135(1):41-55. doi: 10.1182/blood.2019002220. Blood. 2020. PMID: 31697823 Free PMC article.
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