Chin ER - Search Results

1

Discovery of Aficamten (CK-274), a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy.

Chuang C, Collibee S, Ashcraft L, Wang W, Vander Wal M, Wang X, Hwee DT, Wu Y, Wang J, Chin ER, Cremin P, Zamora J, Hartman J, Schaletzky J, Wehri E, Robertson LA, Malik FI, Morgan BP. Chuang C, et al. Among authors: chin er. J Med Chem. 2021 Oct 14;64(19):14142-14152. doi: 10.1021/acs.jmedchem.1c01290. Epub 2021 Oct 4. J Med Chem. 2021. PMID: 34606259 Free article.

2

Defects in sarcolemma repair and skeletal muscle function after injury in a mouse model of Niemann-Pick type A/B disease.

Michailowsky V, Li H, Mittra B, Iyer SR, Mazála DAG, Corrotte M, Wang Y, Chin ER, Lovering RM, Andrews NW. Michailowsky V, et al. Among authors: chin er. Skelet Muscle. 2019 Jan 5;9(1):1. doi: 10.1186/s13395-018-0187-5. Skelet Muscle. 2019. PMID: 30611303 Free PMC article.

3

The SH3 and cysteine-rich domain 3 (Stac3) gene is important to growth, fiber composition, and calcium release from the sarcoplasmic reticulum in postnatal skeletal muscle.

Cong X, Doering J, Mazala DA, Chin ER, Grange RW, Jiang H. Cong X, et al. Among authors: chin er. Skelet Muscle. 2016 Apr 11;6:17. doi: 10.1186/s13395-016-0088-4. eCollection 2016. Skelet Muscle. 2016. PMID: 27073615 Free PMC article.

4

The role of proteases in excitation-contraction coupling failure in muscular dystrophy.

Mázala DA, Grange RW, Chin ER. Mázala DA, et al. Among authors: chin er. Am J Physiol Cell Physiol. 2015 Jan 1;308(1):C33-40. doi: 10.1152/ajpcell.00267.2013. Epub 2014 Oct 8. Am J Physiol Cell Physiol. 2015. PMID: 25298424 Free PMC article.

5

SERCA1 overexpression minimizes skeletal muscle damage in dystrophic mouse models.

Mázala DA, Pratt SJP, Chen D, Molkentin JD, Lovering RM, Chin ER. Mázala DA, et al. Among authors: chin er. Am J Physiol Cell Physiol. 2015 May 1;308(9):C699-709. doi: 10.1152/ajpcell.00341.2014. Epub 2015 Feb 4. Am J Physiol Cell Physiol. 2015. PMID: 25652448 Free PMC article.

6

Perturbations in intracellular Ca2+ handling in skeletal muscle in the G93A*SOD1 mouse model of amyotrophic lateral sclerosis.

Chin ER, Chen D, Bobyk KD, Mázala DA. Chin ER, et al. Am J Physiol Cell Physiol. 2014 Dec 1;307(11):C1031-8. doi: 10.1152/ajpcell.00237.2013. Epub 2014 Sep 24. Am J Physiol Cell Physiol. 2014. PMID: 25252949 Free PMC article.

7

Activation of the endoplasmic reticulum stress response in skeletal muscle of G93A*SOD1 amyotrophic lateral sclerosis mice.

Chen D, Wang Y, Chin ER. Chen D, et al. Among authors: chin er. Front Cell Neurosci. 2015 May 18;9:170. doi: 10.3389/fncel.2015.00170. eCollection 2015. Front Cell Neurosci. 2015. PMID: 26041991 Free PMC article.

8

NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation.

Ryu D, Zhang H, Ropelle ER, Sorrentino V, Mázala DA, Mouchiroud L, Marshall PL, Campbell MD, Ali AS, Knowels GM, Bellemin S, Iyer SR, Wang X, Gariani K, Sauve AA, Cantó C, Conley KE, Walter L, Lovering RM, Chin ER, Jasmin BJ, Marcinek DJ, Menzies KJ, Auwerx J. Ryu D, et al. Among authors: chin er. Sci Transl Med. 2016 Oct 19;8(361):361ra139. doi: 10.1126/scitranslmed.aaf5504. Sci Transl Med. 2016. PMID: 27798264 Free PMC article.

9

Calcium dysregulation, functional calpainopathy, and endoplasmic reticulum stress in sporadic inclusion body myositis.

Amici DR, Pinal-Fernandez I, Mázala DA, Lloyd TE, Corse AM, Christopher-Stine L, Mammen AL, Chin ER. Amici DR, et al. Among authors: chin er. Acta Neuropathol Commun. 2017 Mar 22;5(1):24. doi: 10.1186/s40478-017-0427-7. Acta Neuropathol Commun. 2017. PMID: 28330496 Free PMC article.

10

Using a novel coculture model to dissect the role of intramuscular lipid load on skeletal muscle insulin responsiveness under reduced estrogen conditions.

Wohlers LM, Powers BL, Chin ER, Spangenburg EE. Wohlers LM, et al. Among authors: chin er. Am J Physiol Endocrinol Metab. 2013 Jun 1;304(11):E1199-212. doi: 10.1152/ajpendo.00617.2012. Epub 2013 Apr 2. Am J Physiol Endocrinol Metab. 2013. PMID: 23548610 Free PMC article.

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