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Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective.
Seifert M, Bera SC, van Nies P, Kirchdoerfer RN, Shannon A, Le TT, Meng X, Xia H, Wood JM, Harris LD, Papini FS, Arnold JJ, Almo S, Grove TL, Shi PY, Xiang Y, Canard B, Depken M, Cameron CE, Dulin D. Seifert M, et al. Among authors: shannon a. Elife. 2021 Oct 7;10:e70968. doi: 10.7554/eLife.70968. Elife. 2021. PMID: 34617885 Free PMC article.
Favipiravir strikes the SARS-CoV-2 at its Achilles heel, the RNA polymerase.
Shannon A, Selisko B, Le N, Huchting J, Touret F, Piorkowski G, Fattorini V, Ferron F, Decroly E, Meier C, Coutard B, Peersen O, Canard B. Shannon A, et al. bioRxiv [Preprint]. 2020 May 15:2020.05.15.098731. doi: 10.1101/2020.05.15.098731. bioRxiv. 2020. PMID: 32511380 Free PMC article. Preprint.
Drugs against SARS-CoV-2: What do we know about their mode of action?
Valle C, Martin B, Touret F, Shannon A, Canard B, Guillemot JC, Coutard B, Decroly E. Valle C, et al. Among authors: shannon a. Rev Med Virol. 2020 Nov;30(6):1-10. doi: 10.1002/rmv.2143. Epub 2020 Aug 11. Rev Med Virol. 2020. PMID: 32779326 Free PMC article. Review.
Inhibition of SARS-CoV-2 polymerase by nucleotide analogs: a single molecule perspective.
Seifert M, Bera SC, van Nies P, Kirchdoerfer RN, Shannon A, Le TT, Meng X, Xia H, Wood JM, Harris LD, Papini FS, Arnold JJ, Almo SC, Grove TL, Shi PY, Xiang Y, Canard B, Depken M, Cameron CE, Dulin D. Seifert M, et al. Among authors: shannon a. bioRxiv [Preprint]. 2021 Apr 8:2020.08.06.240325. doi: 10.1101/2020.08.06.240325. bioRxiv. 2021. Update in: Elife. 2021 Oct 07;10:e70968. doi: 10.7554/eLife.70968 PMID: 33851161 Free PMC article. Updated. Preprint.
324 results