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Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms.
Hu H, Piotrowska Z, Hare PJ, Chen H, Mulvey HE, Mayfield A, Noeen S, Kattermann K, Greenberg M, Williams A, Riley AK, Wilson JJ, Mao YQ, Huang RP, Banwait MK, Ho J, Crowther GS, Hariri LP, Heist RS, Kodack DP, Pinello L, Shaw AT, Mino-Kenudson M, Hata AN, Sequist LV, Benes CH, Niederst MJ, Engelman JA. Hu H, et al. Among authors: williams a. Cancer Cell. 2021 Nov 8;39(11):1531-1547.e10. doi: 10.1016/j.ccell.2021.09.003. Epub 2021 Oct 7. Cancer Cell. 2021. PMID: 34624218 Free PMC article.
Targeting FGFR overcomes EMT-mediated resistance in EGFR mutant non-small cell lung cancer.
Raoof S, Mulford IJ, Frisco-Cabanos H, Nangia V, Timonina D, Labrot E, Hafeez N, Bilton SJ, Drier Y, Ji F, Greenberg M, Williams A, Kattermann K, Damon L, Sovath S, Rakiec DP, Korn JM, Ruddy DA, Benes CH, Hammerman PS, Piotrowska Z, Sequist LV, Niederst MJ, Barretina J, Engelman JA, Hata AN. Raoof S, et al. Among authors: williams a. Oncogene. 2019 Sep;38(37):6399-6413. doi: 10.1038/s41388-019-0887-2. Epub 2019 Jul 19. Oncogene. 2019. PMID: 31324888 Free PMC article.
NOTCH1 Represses MCL-1 Levels in GSI-resistant T-ALL, Making them Susceptible to ABT-263.
Dastur A, Choi A, Costa C, Yin X, Williams A, McClanaghan J, Greenberg M, Roderick J, Patel NU, Boisvert J, McDermott U, Garnett MJ, Almenara J, Grant S, Rizzo K, Engelman JA, Kelliher M, Faber AC, Benes CH. Dastur A, et al. Among authors: williams a. Clin Cancer Res. 2019 Jan 1;25(1):312-324. doi: 10.1158/1078-0432.CCR-18-0867. Epub 2018 Sep 17. Clin Cancer Res. 2019. PMID: 30224339 Free PMC article.
Identification and characterization of substrate- and product-selective nylon hydrolases.
Drufva EE, Cahill JF, Saint-Vincent PMB, Williams AN, Bocharova V, Capra N, Meilleur F, Carper DL, Bourgery C, Miyazaki K, Yonemura M, Shiraishi Y, Parks JM, Zhou M, Dishner IT, Foster JC, Koehler SJ, Valentino HR, Sedova A, Kertesz V, Vasileva DP, Hochanadel LH, Figg CA, Negoro S, Kato DI, Chen SH, Michener JK. Drufva EE, et al. Among authors: williams an. bioRxiv [Preprint]. 2024 Nov 14:2024.11.14.623603. doi: 10.1101/2024.11.14.623603. bioRxiv. 2024. PMID: 39605696 Free PMC article. Preprint.
Dose-Related Mutagenic and Clastogenic Effects of Benzo[b]fluoranthene in Mouse Somatic Tissues Detected by Duplex Sequencing and the Micronucleus Assay.
Schuster DM, LeBlanc DPM, Zhou G, Meier MJ, Dodge AE, White PA, Long AS, Williams A, Hobbs C, Diesing A, Smith-Roe SL, Salk JJ, Marchetti F, Yauk CL. Schuster DM, et al. Among authors: williams a. Environ Sci Technol. 2024 Nov 27. doi: 10.1021/acs.est.4c07236. Online ahead of print. Environ Sci Technol. 2024. PMID: 39602390
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