Downward J - Search Results

1

Characterisation of tumour microenvironment remodelling following oncogene inhibition in preclinical studies with imaging mass cytometry.

van Maldegem F, Valand K, Cole M, Patel H, Angelova M, Rana S, Colliver E, Enfield K, Bah N, Kelly G, Tsang VSK, Mugarza E, Moore C, Hobson P, Levi D, Molina-Arcas M, Swanton C, Downward J. van Maldegem F, et al. Among authors: downward j. Nat Commun. 2021 Oct 8;12(1):5906. doi: 10.1038/s41467-021-26214-x. Nat Commun. 2021. PMID: 34625563 Free PMC article.

2

RNA interference, DNA methylation, and gene silencing: a bright future for cancer therapy?

Swanton C, Nicke B, Downward J. Swanton C, et al. Among authors: downward j. Lancet Oncol. 2004 Nov;5(11):653-4. doi: 10.1016/S1470-2045(04)01604-3. Lancet Oncol. 2004. PMID: 15522650 No abstract available.

3

Chromosomal instability, colorectal cancer and taxane resistance.

Swanton C, Tomlinson I, Downward J. Swanton C, et al. Among authors: downward j. Cell Cycle. 2006 Apr;5(8):818-23. doi: 10.4161/cc.5.8.2682. Epub 2006 Apr 17. Cell Cycle. 2006. PMID: 16628000 Review.

4

Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs.

Swanton C, Marani M, Pardo O, Warne PH, Kelly G, Sahai E, Elustondo F, Chang J, Temple J, Ahmed AA, Brenton JD, Downward J, Nicke B. Swanton C, et al. Among authors: downward j. Cancer Cell. 2007 Jun;11(6):498-512. doi: 10.1016/j.ccr.2007.04.011. Cancer Cell. 2007. PMID: 17560332 Free article.

5

Initiation of high frequency multi-drug resistance following kinase targeting by siRNAs.

Swanton C, Nicke B, Marani M, Kelly G, Downward J. Swanton C, et al. Among authors: downward j. Cell Cycle. 2007 Aug 15;6(16):2001-4. doi: 10.4161/cc.6.16.4538. Epub 2007 Jun 4. Cell Cycle. 2007. PMID: 17721083

6

Unraveling the complexity of endocrine resistance in breast cancer by functional genomics.

Swanton C, Downward J. Swanton C, et al. Among authors: downward j. Cancer Cell. 2008 Feb;13(2):83-5. doi: 10.1016/j.ccr.2008.01.021. Cancer Cell. 2008. PMID: 18242507 Free article.

7

Functional genomic analysis of drug sensitivity pathways to guide adjuvant strategies in breast cancer.

Swanton C, Szallasi Z, Brenton JD, Downward J. Swanton C, et al. Among authors: downward j. Breast Cancer Res. 2008;10(5):214. doi: 10.1186/bcr2159. Epub 2008 Oct 31. Breast Cancer Res. 2008. PMID: 18986507 Free PMC article. Review.

8

How to fool a wonder drug: truncate and dimerize.

Molina-Arcas M, Downward J. Molina-Arcas M, et al. Among authors: downward j. Cancer Cell. 2012 Jan 17;21(1):7-9. doi: 10.1016/j.ccr.2011.12.017. Cancer Cell. 2012. PMID: 22264784 Free article.

9

The GATA2 transcriptional network is requisite for RAS oncogene-driven non-small cell lung cancer.

Kumar MS, Hancock DC, Molina-Arcas M, Steckel M, East P, Diefenbacher M, Armenteros-Monterroso E, Lassailly F, Matthews N, Nye E, Stamp G, Behrens A, Downward J. Kumar MS, et al. Among authors: downward j. Cell. 2012 Apr 27;149(3):642-55. doi: 10.1016/j.cell.2012.02.059. Cell. 2012. PMID: 22541434 Free article.

10

Determination of synthetic lethal interactions in KRAS oncogene-dependent cancer cells reveals novel therapeutic targeting strategies.

Steckel M, Molina-Arcas M, Weigelt B, Marani M, Warne PH, Kuznetsov H, Kelly G, Saunders B, Howell M, Downward J, Hancock DC. Steckel M, et al. Among authors: downward j. Cell Res. 2012 Aug;22(8):1227-45. doi: 10.1038/cr.2012.82. Epub 2012 May 22. Cell Res. 2012. PMID: 22613949 Free PMC article.

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