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Sequestration by IFIT1 impairs translation of 2'O-unmethylated capped RNA.
Habjan M, Hubel P, Lacerda L, Benda C, Holze C, Eberl CH, Mann A, Kindler E, Gil-Cruz C, Ziebuhr J, Thiel V, Pichlmair A. Habjan M, et al. Among authors: pichlmair a. PLoS Pathog. 2013;9(10):e1003663. doi: 10.1371/journal.ppat.1003663. Epub 2013 Oct 3. PLoS Pathog. 2013. PMID: 24098121 Free PMC article.
Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway.
Holze C, Michaudel C, Mackowiak C, Haas DA, Benda C, Hubel P, Pennemann FL, Schnepf D, Wettmarshausen J, Braun M, Leung DW, Amarasinghe GK, Perocchi F, Staeheli P, Ryffel B, Pichlmair A. Holze C, et al. Among authors: pichlmair a. Nat Immunol. 2018 Feb;19(2):130-140. doi: 10.1038/s41590-017-0013-y. Epub 2017 Dec 18. Nat Immunol. 2018. PMID: 29255269 Free PMC article.
The alternative cap-binding complex is required for antiviral defense in vivo.
Gebhardt A, Bergant V, Schnepf D, Moser M, Meiler A, Togbe D, Mackowiak C, Reinert LS, Paludan SR, Ryffel B, Stukalov A, Staeheli P, Pichlmair A. Gebhardt A, et al. Among authors: pichlmair a. PLoS Pathog. 2019 Dec 19;15(12):e1008155. doi: 10.1371/journal.ppat.1008155. eCollection 2019 Dec. PLoS Pathog. 2019. PMID: 31856218 Free PMC article.
The UFM1 Pathway Impacts HCMV US2-Mediated Degradation of HLA Class I.
Schuren ABC, Boer IGJ, Bouma EM, Van de Weijer ML, Costa AI, Hubel P, Pichlmair A, Lebbink RJ, Wiertz EJHJ. Schuren ABC, et al. Among authors: pichlmair a. Molecules. 2021 Jan 8;26(2):287. doi: 10.3390/molecules26020287. Molecules. 2021. PMID: 33430125 Free PMC article.
Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.
Stukalov A, Girault V, Grass V, Karayel O, Bergant V, Urban C, Haas DA, Huang Y, Oubraham L, Wang A, Hamad MS, Piras A, Hansen FM, Tanzer MC, Paron I, Zinzula L, Engleitner T, Reinecke M, Lavacca TM, Ehmann R, Wölfel R, Jores J, Kuster B, Protzer U, Rad R, Ziebuhr J, Thiel V, Scaturro P, Mann M, Pichlmair A. Stukalov A, et al. Among authors: pichlmair a. Nature. 2021 Jun;594(7862):246-252. doi: 10.1038/s41586-021-03493-4. Epub 2021 Apr 12. Nature. 2021. PMID: 33845483
Disruption of disulfides within RBD of SARS-CoV-2 spike protein prevents fusion and represents a target for viral entry inhibition by registered drugs.
Manček-Keber M, Hafner-Bratkovič I, Lainšček D, Benčina M, Govednik T, Orehek S, Plaper T, Jazbec V, Bergant V, Grass V, Pichlmair A, Jerala R. Manček-Keber M, et al. Among authors: pichlmair a. FASEB J. 2021 Jun;35(6):e21651. doi: 10.1096/fj.202100560R. FASEB J. 2021. PMID: 34004056 Free PMC article.
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