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The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders.
Chang H, Hoshina N, Zhang C, Ma Y, Cao H, Wang Y, Wu DD, Bergen SE, Landén M, Hultman CM, Preisig M, Kutalik Z, Castelao E, Grigoroiu-Serbanescu M, Forstner AJ, Strohmaier J, Hecker J, Schulze TG, Müller-Myhsok B, Reif A, Mitchell PB, Martin NG, Schofield PR, Cichon S, Nöthen MM; Swedish Bipolar Study Group; MooDS Bipolar Consortium; Walter H, Erk S, Heinz A, Amin N, van Duijn CM, Meyer-Lindenberg A, Tost H, Xiao X, Yamamoto T, Rietschel M, Li M. Chang H, et al. Mol Psychiatry. 2018 Feb;23(2):400-412. doi: 10.1038/mp.2016.231. Epub 2017 Jan 10. Mol Psychiatry. 2018. PMID: 28070120 Free PMC article.
Independent replications and integrative analyses confirm TRANK1 as a susceptibility gene for bipolar disorder.
Li W, Cai X, Li HJ, Song M, Zhang CY, Yang Y, Zhang L, Zhao L, Liu W, Wang L, Shao M, Zhang Y, Zhang C, Cai J, Zhou DS, Li X, Hui L, Jia QF, Qu N, Zhong BL, Zhang SF, Chen J, Xia B, Li Y, Song X, Fan W, Tang W, Tang W, Tang J, Chen X, Yue W, Zhang D, Fang Y, Xiao X, Li M, Lv L, Chang H. Li W, et al. Among authors: zhang cy, zhang l, zhang c, zhang d, zhang sf, zhang y. Neuropsychopharmacology. 2021 May;46(6):1103-1112. doi: 10.1038/s41386-020-00788-4. Epub 2020 Aug 13. Neuropsychopharmacology. 2021. PMID: 32791513 Free PMC article.
Novel Risk Loci Associated With Genetic Risk for Bipolar Disorder Among Han Chinese Individuals: A Genome-Wide Association Study and Meta-analysis.
Li HJ, Zhang C, Hui L, Zhou DS, Li Y, Zhang CY, Wang C, Wang L, Li W, Yang Y, Qu N, Tang J, He Y, Zhou J, Yang Z, Li X, Cai J, Yang L, Chen J, Fan W, Tang W, Tang W, Jia QF, Liu W, Zhuo C, Song X, Liu F, Bai Y, Zhong BL, Zhang SF, Chen J, Xia B, Lv L, Liu Z, Hu S, Li XY, Liu JW, Cai X, Yao YG, Zhang Y, Yan H, Chang S, Zhao JP, Yue WH, Luo XJ, Chen X, Xiao X, Fang Y, Li M; GeseDNA Research Team. Li HJ, et al. Among authors: zhang cy, zhang c, zhang sf, zhang y. JAMA Psychiatry. 2021 Mar 1;78(3):320-330. doi: 10.1001/jamapsychiatry.2020.3738. JAMA Psychiatry. 2021. PMID: 33263727 Free PMC article.
2,169 results