Tatton MR - Search Results

1

Exploration of a Nitromethane-Carbonylation Strategy during Route Design of an Atropisomeric KRAS^G12C Inhibitor.

Douglas JJ, Tatton MR, de Bruin D, Buttar D, Cook C, Dai K, Ferrer C, Leslie K, Morrison J, Munday R, Ronson TO, Zhao H. Douglas JJ, et al. Among authors: tatton mr. J Org Chem. 2022 Feb 18;87(4):2075-2086. doi: 10.1021/acs.joc.1c01736. Epub 2021 Oct 15. J Org Chem. 2022. PMID: 34652911

2

Approaches to Synthesis and Isolation of Enantiomerically Pure Biologically Active Atropisomers.

Carlsson AC, Karlsson S, Munday RH, Tatton MR. Carlsson AC, et al. Among authors: tatton mr. Acc Chem Res. 2022 Oct 18;55(20):2938-2948. doi: 10.1021/acs.accounts.2c00513. Epub 2022 Oct 4. Acc Chem Res. 2022. PMID: 36194144

3

Total synthesis of the antitumor antibiotic (±)-streptonigrin: first- and second-generation routes for de novo pyridine formation using ring-closing metathesis.

Donohoe TJ, Jones CR, Kornahrens AF, Barbosa LC, Walport LJ, Tatton MR, O'Hagan M, Rathi AH, Baker DB. Donohoe TJ, et al. Among authors: tatton mr. J Org Chem. 2013 Dec 20;78(24):12338-50. doi: 10.1021/jo402388f. Epub 2013 Dec 12. J Org Chem. 2013. PMID: 24328139 Free PMC article.

4

NHC Catalysis for Umpolung Pyridinium Alkylation via Deoxy-Breslow Intermediates.

Wu T, Tatton MR, Greaney MF. Wu T, et al. Among authors: tatton mr. Angew Chem Int Ed Engl. 2022 Apr 4;61(15):e202117524. doi: 10.1002/anie.202117524. Epub 2022 Feb 18. Angew Chem Int Ed Engl. 2022. PMID: 35103381 Free PMC article.

5

Synthesis of functionalized cyanopyrazoles via magnesium bases.

Dishington A, Feron JL, Gill K, Graham MA, Hollingsworth I, Pink JH, Roberts A, Simpson I, Tatton M. Dishington A, et al. Org Lett. 2014 Dec 5;16(23):6120-3. doi: 10.1021/ol502977a. Epub 2014 Nov 13. Org Lett. 2014. PMID: 25393394

6

Palladium-catalyzed enolate arylation as a key C-C bond-forming reaction for the synthesis of isoquinolines.

Pilgrim BS, Gatland AE, Esteves CH, McTernan CT, Jones GR, Tatton MR, Procopiou PA, Donohoe TJ. Pilgrim BS, et al. Among authors: tatton mr. Org Biomol Chem. 2016 Jan 21;14(3):1065-90. doi: 10.1039/c5ob02320c. Epub 2015 Dec 3. Org Biomol Chem. 2016. PMID: 26632484

7

De novo synthesis of multisubstituted aryl amines using alkene cross metathesis.

Tatton MR, Simpson I, Donohoe TJ. Tatton MR, et al. Org Lett. 2014 Apr 4;16(7):1920-3. doi: 10.1021/ol500441q. Epub 2014 Mar 19. Org Lett. 2014. PMID: 24646289 Free PMC article.

8

A short and efficient synthesis of neodysiherbaine A by using catalytic oxidative cyclization.

Donohoe TJ, Winship PC, Tatton MR, Szeto P. Donohoe TJ, et al. Among authors: tatton mr. Angew Chem Int Ed Engl. 2011 Aug 8;50(33):7604-6. doi: 10.1002/anie.201102525. Epub 2011 Jun 27. Angew Chem Int Ed Engl. 2011. PMID: 21710669 No abstract available.

9

New methods for the synthesis of naphthyl amines; application to the synthesis of dihydrosanguinarine, sanguinarine, oxysanguinarine and (±)-maclekarpines B and C.

Tatton MR, Simpson I, Donohoe TJ. Tatton MR, et al. Chem Commun (Camb). 2014 Oct 7;50(77):11314-6. doi: 10.1039/c4cc05209a. Chem Commun (Camb). 2014. PMID: 25116797

10

NHC Catalysis for Umpolung Pyridinium Alkylation via Deoxy-Breslow Intermediates.

Wu T, Tatton MR, Greaney MF. Wu T, et al. Among authors: tatton mr. Angew Chem Weinheim Bergstr Ger. 2022 Apr 4;134(15):e202117524. doi: 10.1002/ange.202117524. Epub 2022 Feb 18. Angew Chem Weinheim Bergstr Ger. 2022. PMID: 38504766 Free PMC article.

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