Brekken RA - Search Results

1

AXL Inhibitor TP-0903 Reduces Metastasis and Therapy Resistance in Pancreatic Cancer.

Zhang Y, Arner EN, Rizvi A, Toombs JE, Huang H, Warner SL, Foulks JM, Brekken RA. Zhang Y, et al. Among authors: brekken ra. Mol Cancer Ther. 2022 Jan;21(1):38-47. doi: 10.1158/1535-7163.MCT-21-0293. Epub 2021 Oct 21. Mol Cancer Ther. 2022. PMID: 34675118 Free PMC article.

2

Molecular consequences of silencing mutant K-ras in pancreatic cancer cells: justification for K-ras-directed therapy.

Fleming JB, Shen GL, Holloway SE, Davis M, Brekken RA. Fleming JB, et al. Among authors: brekken ra. Mol Cancer Res. 2005 Jul;3(7):413-23. doi: 10.1158/1541-7786.MCR-04-0206. Mol Cancer Res. 2005. PMID: 16046552

3

Combination of a monoclonal anti-phosphatidylserine antibody with gemcitabine strongly inhibits the growth and metastasis of orthotopic pancreatic tumors in mice.

Beck AW, Luster TA, Miller AF, Holloway SE, Conner CR, Barnett CC, Thorpe PE, Fleming JB, Brekken RA. Beck AW, et al. Among authors: brekken ra. Int J Cancer. 2006 May 15;118(10):2639-43. doi: 10.1002/ijc.21684. Int J Cancer. 2006. PMID: 16353142

4

Forced expression of MMP9 rescues the loss of angiogenesis and abrogates metastasis of pancreatic tumors triggered by the absence of host SPARC.

Arnold S, Mira E, Muneer S, Korpanty G, Beck AW, Holloway SE, Mañes S, Brekken RA. Arnold S, et al. Among authors: brekken ra. Exp Biol Med (Maywood). 2008 Jul;233(7):860-73. doi: 10.3181/0801-RM-12. Epub 2008 Apr 29. Exp Biol Med (Maywood). 2008. PMID: 18445772 Free PMC article.

5

Vascular endothelial growth factor receptor 2 mediates macrophage infiltration into orthotopic pancreatic tumors in mice.

Dineen SP, Lynn KD, Holloway SE, Miller AF, Sullivan JP, Shames DS, Beck AW, Barnett CC, Fleming JB, Brekken RA. Dineen SP, et al. Among authors: brekken ra. Cancer Res. 2008 Jun 1;68(11):4340-6. doi: 10.1158/0008-5472.CAN-07-6705. Cancer Res. 2008. PMID: 18519694

6

The acellular fraction of stored platelets promotes tumor cell invasion.

Dineen SP, Roland CL, Toombs JE, Kelher M, Silliman CC, Brekken RA, Barnett CC Jr. Dineen SP, et al. Among authors: brekken ra. J Surg Res. 2009 May 1;153(1):132-7. doi: 10.1016/j.jss.2008.04.013. Epub 2008 May 7. J Surg Res. 2009. PMID: 18541268

7

The Adnectin CT-322 is a novel VEGF receptor 2 inhibitor that decreases tumor burden in an orthotopic mouse model of pancreatic cancer.

Dineen SP, Sullivan LA, Beck AW, Miller AF, Carbon JG, Mamluk R, Wong H, Brekken RA. Dineen SP, et al. Among authors: brekken ra. BMC Cancer. 2008 Nov 27;8:352. doi: 10.1186/1471-2407-8-352. BMC Cancer. 2008. PMID: 19038046 Free PMC article.

8

Inhibition of vascular endothelial growth factor reduces angiogenesis and modulates immune cell infiltration of orthotopic breast cancer xenografts.

Roland CL, Dineen SP, Lynn KD, Sullivan LA, Dellinger MT, Sadegh L, Sullivan JP, Shames DS, Brekken RA. Roland CL, et al. Among authors: brekken ra. Mol Cancer Ther. 2009 Jul;8(7):1761-71. doi: 10.1158/1535-7163.MCT-09-0280. Epub 2009 Jun 30. Mol Cancer Ther. 2009. PMID: 19567820

9

Cytokine levels correlate with immune cell infiltration after anti-VEGF therapy in preclinical mouse models of breast cancer.

Roland CL, Lynn KD, Toombs JE, Dineen SP, Udugamasooriya DG, Brekken RA. Roland CL, et al. Among authors: brekken ra. PLoS One. 2009 Nov 3;4(11):e7669. doi: 10.1371/journal.pone.0007669. PLoS One. 2009. PMID: 19888452 Free PMC article.

10

Smac mimetic increases chemotherapy response and improves survival in mice with pancreatic cancer.

Dineen SP, Roland CL, Greer R, Carbon JG, Toombs JE, Gupta P, Bardeesy N, Sun H, Williams N, Minna JD, Brekken RA. Dineen SP, et al. Among authors: brekken ra. Cancer Res. 2010 Apr 1;70(7):2852-61. doi: 10.1158/0008-5472.CAN-09-3892. Epub 2010 Mar 23. Cancer Res. 2010. PMID: 20332237 Free PMC article.

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