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Expression of the αVβ3 integrin affects prostate cancer sEV cargo and density and promotes sEV pro-tumorigenic activity in vivo through a GPI-anchored receptor, NgR2.
Verrillo CE, Quaglia F, Shields CD, Lin S, Kossenkov AV, Tang HY, Speicher D, Naranjo NM, Testa A, Kelly WK, Liu Q, Leiby B, Musante L, Sossey-Alaoui K, Dogra N, Chen TY, Altieri DC, Languino LR. Verrillo CE, et al. Among authors: naranjo nm. J Extracell Vesicles. 2024 Aug;13(8):e12482. doi: 10.1002/jev2.12482. J Extracell Vesicles. 2024. PMID: 39105261 Free PMC article.
Neuroendocrine gene subsets are uniquely dysregulated in prostate adenocarcinoma.
Naranjo NM, Kennedy A, Testa A, Verrillo CE, Altieri AD, Kean R, Hooper DC, Yu J, Zhao J, Abinader O, Pickles MW, Hawkins A, Kelly WK, Mitra R, Languino LR. Naranjo NM, et al. Cancer Biol Ther. 2024 Dec 31;25(1):2364433. doi: 10.1080/15384047.2024.2364433. Epub 2024 Jun 26. Cancer Biol Ther. 2024. PMID: 38926911 Free PMC article.
Targeting the αVβ3/NgR2 pathway in neuroendocrine prostate cancer.
Testa A, Quaglia F, Naranjo NM, Verrillo CE, Shields CD, Lin S, Pickles MW, Hamza DF, Von Schalscha T, Cheresh DA, Leiby B, Liu Q, Ding J, Kelly WK, Hooper DC, Corey E, Plow EF, Altieri DC, Languino LR. Testa A, et al. Among authors: naranjo nm. Matrix Biol. 2023 Dec;124:49-62. doi: 10.1016/j.matbio.2023.11.003. Epub 2023 Nov 11. Matrix Biol. 2023. PMID: 37956856 Free PMC article.
Small extracellular vesicle-mediated ITGB6 siRNA delivery downregulates the αVβ6 integrin and inhibits adhesion and migration of recipient prostate cancer cells.
Krishn SR, Garcia V, Naranjo NM, Quaglia F, Shields CD, Harris MA, Kossenkov AV, Liu Q, Corey E, Altieri DC, Languino LR. Krishn SR, et al. Among authors: naranjo nm. Cancer Biol Ther. 2022 Dec 31;23(1):173-185. doi: 10.1080/15384047.2022.2030622. Cancer Biol Ther. 2022. PMID: 35188070 Free PMC article.
The Clinical outcomes, healthcare resource utilization, and related costs (COHERENT) model. Application in heart failure patients.
Bueno H, Bernal JL, Jiménez-Jiménez V, Martín-Sánchez FJ, Rossello X, Moreno G, Goñi C, Gil V, Llorens P, Naranjo N, Jacob J, Herrero-Puente P, Garrote S, Silla-Castro JC, Pocock SJ, Miró Ò; ICA-SEMES ad hoc COHERENT study group. Bueno H, et al. Among authors: naranjo n. Rev Esp Cardiol (Engl Ed). 2022 Jul;75(7):585-594. doi: 10.1016/j.rec.2021.08.009. Epub 2021 Oct 20. Rev Esp Cardiol (Engl Ed). 2022. PMID: 34688580 English, Spanish.
Skin Cancer and Dermoscopy Training for Primary Care Physicians: A Pilot Study.
De Bedout V, Williams NM, Muñoz AM, Londoño AM, Munera M, Naranjo N, Rodriguez LM, Toro AM, Miao F, Koru-Sengul T, Jaimes N. De Bedout V, et al. Among authors: naranjo n. Dermatol Pract Concept. 2021 Jan 29;11(1):e2021145. doi: 10.5826/dpc.1101a145. eCollection 2021 Jan. Dermatol Pract Concept. 2021. PMID: 33614219 Free PMC article.
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