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Functional reprogramming of regulatory T cells in the absence of Foxp3.
Charbonnier LM, Cui Y, Stephen-Victor E, Harb H, Lopez D, Bleesing JJ, Garcia-Lloret MI, Chen K, Ozen A, Carmeliet P, Li MO, Pellegrini M, Chatila TA. Charbonnier LM, et al. Among authors: chen k. Nat Immunol. 2019 Sep;20(9):1208-1219. doi: 10.1038/s41590-019-0442-x. Epub 2019 Aug 5. Nat Immunol. 2019. PMID: 31384057 Free PMC article.
Nfkb2 variants reveal a p100-degradation threshold that defines autoimmune susceptibility.
Wirasinha RC, Davies AR, Srivastava M, Sheridan JM, Sng XYX, Delmonte OM, Dobbs K, Loh KL, Miosge LA, Lee CE, Chand R, Chan A, Yap JY, Keller MD, Chen K, Rossjohn J, La Gruta NL, Vinuesa CG, Reid HH, Lionakis MS, Notarangelo LD, Gray DHD, Goodnow CC, Cook MC, Daley SR. Wirasinha RC, et al. Among authors: chen k. J Exp Med. 2021 Feb 1;218(2):e20200476. doi: 10.1084/jem.20200476. J Exp Med. 2021. PMID: 33107914 Free PMC article.
Single-cell analysis of FOXP3 deficiencies in humans and mice unmasks intrinsic and extrinsic CD4+ T cell perturbations.
Zemmour D, Charbonnier LM, Leon J, Six E, Keles S, Delville M, Benamar M, Baris S, Zuber J, Chen K, Neven B, Garcia-Lloret MI, Ruemmele FM, Brugnara C, Cerf-Bensussan N, Rieux-Laucat F, Cavazzana M, André I, Chatila TA, Mathis D, Benoist C. Zemmour D, et al. Among authors: chen k. Nat Immunol. 2021 May;22(5):607-619. doi: 10.1038/s41590-021-00910-8. Epub 2021 Apr 8. Nat Immunol. 2021. PMID: 33833438 Free PMC article.
Lymphoma in Partial DiGeorge Syndrome: Report of 2 Cases.
Lozano-Chinga M, Diaz-Cabrera N, Khimani F, Chen K, Bohnsack J, Walter JE, Tabatabaian F, Afify Z. Lozano-Chinga M, et al. Among authors: chen k. J Pediatr Hematol Oncol. 2022 Apr 1;44(3):e819-e822. doi: 10.1097/MPH.0000000000002388. J Pediatr Hematol Oncol. 2022. PMID: 34966099
STAT6 joins the gain-of-function club.
Chen K, Ochs HD, Allenspach EJ. Chen K, et al. J Allergy Clin Immunol. 2023 Jul;152(1):53-55. doi: 10.1016/j.jaci.2023.05.003. Epub 2023 May 14. J Allergy Clin Immunol. 2023. PMID: 37192684 No abstract available.
Diagnostic interpretation of genetic studies in patients with primary immunodeficiency diseases: A working group report of the Primary Immunodeficiency Diseases Committee of the American Academy of Allergy, Asthma & Immunology.
Chinn IK, Chan AY, Chen K, Chou J, Dorsey MJ, Hajjar J, Jongco AM 3rd, Keller MD, Kobrynski LJ, Kumanovics A, Lawrence MG, Leiding JW, Lugar PL, Orange JS, Patel K, Platt CD, Puck JM, Raje N, Romberg N, Slack MA, Sullivan KE, Tarrant TK, Torgerson TR, Walter JE. Chinn IK, et al. Among authors: chen k. J Allergy Clin Immunol. 2020 Jan;145(1):46-69. doi: 10.1016/j.jaci.2019.09.009. Epub 2019 Sep 27. J Allergy Clin Immunol. 2020. PMID: 31568798 Review.
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