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Page 1
Bivalent binding of a fully human IgG to the SARS-CoV-2 spike proteins reveals mechanisms of potent neutralization.
Wang B, Asarnow D, Lee WH, Huang CW, Faust B, Ng PML, Ngoh EZX, Bohn M, Bulkley D, Pizzorno A, Tan HC, Lee CY, Minhat RA, Terrier O, Soh MK, Teo FJ, Yeap YYC, Hu Y, Seah SGK, Maurer-Stroh S, Renia L, Hanson BJ, Rosa-Calatrava M, Manglik A, Cheng Y, Craik CS, Wang CI. Wang B, et al. Among authors: ngoh ezx. bioRxiv [Preprint]. 2020 Jul 15:2020.07.14.203414. doi: 10.1101/2020.07.14.203414. bioRxiv. 2020. PMID: 32699850 Free PMC article. Preprint.
Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia.
Asarnow D, Wang B, Lee WH, Hu Y, Huang CW, Faust B, Ng PML, Ngoh EZX, Bohn M, Bulkley D, Pizzorno A, Ary B, Tan HC, Lee CY, Minhat RA, Terrier O, Soh MK, Teo FJ, Yeap YYC, Seah SGK, Chan CEZ, Connelly E, Young NJ, Maurer-Stroh S, Renia L, Hanson BJ, Rosa-Calatrava M, Manglik A, Cheng Y, Craik CS, Wang CI. Asarnow D, et al. Among authors: ngoh ezx. Cell. 2021 Jun 10;184(12):3192-3204.e16. doi: 10.1016/j.cell.2021.04.033. Epub 2021 Apr 24. Cell. 2021. PMID: 33974910 Free PMC article.
Resistance of SARS-CoV-2 Delta variant to neutralization by BNT162b2-elicited antibodies in Asians.
Wang B, Goh YS, Fong SW, Young BE, Ngoh EZX, Chavatte JM, Salleh SNM, Yeo NK, Amrun SN, Hor PX, Loh CY, Lee CY, Chan YH, Chang ZW, Tay MZ, Rouers A, Torres-Ruesta A, Carissimo G, Soh MK, Lee RTC, Xu Y, Pada S, Lin RTP, Leo YS, Lye DC, Maurer-Stroh S, Ng LFP, Renia L, Wang CI. Wang B, et al. Among authors: ngoh ezx. Lancet Reg Health West Pac. 2021 Oct;15:100276. doi: 10.1016/j.lanwpc.2021.100276. Epub 2021 Sep 20. Lancet Reg Health West Pac. 2021. PMID: 34568853 Free PMC article. No abstract available.
Decreased memory B cell frequencies in COVID-19 delta variant vaccine breakthrough infection.
Tay MZ, Rouers A, Fong SW, Goh YS, Chan YH, Chang ZW, Xu W, Tan CW, Chia WN, Torres-Ruesta A, Amrun SN, Huang Y, Hor PX, Loh CY, Yeo NK, Wang B, Ngoh EZX, Salleh SNM, Chavatte JM, Lim AJ, Maurer-Stroh S, Wang LF, Lin RVTP, Wang CI, Tan SY, Young BE, Leo YS, Lye DC, Renia L, Ng LF. Tay MZ, et al. Among authors: ngoh ezx. EMBO Mol Med. 2022 Mar 7;14(3):e15227. doi: 10.15252/emmm.202115227. Epub 2022 Jan 21. EMBO Mol Med. 2022. PMID: 34994081 Free PMC article.
Comprehensive engineering of a therapeutic neutralizing antibody targeting SARS-CoV-2 spike protein to neutralize escape variants.
Kuramochi T, Gan SW, Ho AWS, Wang B, Kageji N, Nambu T, Iida S, Okuda-Miura M, Chia WS, Yeo CY, Chen D, Lee WH, Ngoh EZX, Mohd Salleh SN, Wang CI, Igawa T, Shimada H. Kuramochi T, et al. Among authors: ngoh ezx. MAbs. 2022 Jan-Dec;14(1):2040350. doi: 10.1080/19420862.2022.2040350. MAbs. 2022. PMID: 35293276 Free PMC article.
Lower vaccine-acquired immunity in the elderly population following two-dose BNT162b2 vaccination is alleviated by a third vaccine dose.
Renia L, Goh YS, Rouers A, Le Bert N, Chia WN, Chavatte JM, Fong SW, Chang ZW, Zhuo NZ, Tay MZ, Chan YH, Tan CW, Yeo NK, Amrun SN, Huang Y, Wong JXE, Hor PX, Loh CY, Wang B, Ngoh EZX, Salleh SNM, Carissimo G, Dowla S, Lim AJ, Zhang J, Lim JME, Wang CI, Ding Y, Pada S, Sun LJ, Somani J, Lee ES, Ong DLS; SCOPE Cohort Study Group; Leo YS, MacAry PA, Lin RTP, Wang LF, Ren EC, Lye DC, Bertoletti A, Young BE, Ng LFP. Renia L, et al. Among authors: ngoh ezx. Nat Commun. 2022 Aug 8;13(1):4615. doi: 10.1038/s41467-022-32312-1. Nat Commun. 2022. PMID: 35941158 Free PMC article.
Heterologous booster vaccination with CoronaVac following prime vaccination with mRNA vaccine.
Goh YS, Fong SW, Rouers A, Chang ZW, Tay MZ, Chavatte JM, Zhuo NZ, Hor PX, Loh CY, Huang Y, Wong JXE, Tan YJ, Lim DRX, Wang B, Ngoh EZX, Salleh SNM, Lee RTC, Pada S, Sun LJ, Ong DLS, Somani J, Lee ES; NCID Study Group; COVID‐19 Study Group; Maurer-Stroh S, Wang CI, Leo YS, Lin RT, Ren EC, Lye DC, Young BE, Lim PL, Ng LF, Renia L. Goh YS, et al. Among authors: ngoh ezx. Clin Transl Immunology. 2022 Aug 23;11(8):e1403. doi: 10.1002/cti2.1403. eCollection 2022. Clin Transl Immunology. 2022. PMID: 36016852 Free PMC article.
Efficient recall of SARS-CoV-2 variant-reactive B cells and T responses in the elderly upon heterologous mRNA vaccines as boosters.
Rouers A, Wong N, Goh YS, Torres-Ruesta A, Tay MZ, Chang ZW, Fong SW, Neo V, Kam IKJ, Yeo NK, Huang Y, Loh CY, Hor PX, Wong JXE, Tan YJ; COVID-19 Study Group; Macary PA, Qian X, Bei W, Ngoh EZX, Salleh SNM, Wang CI, Poh XY, Rao S, Chia PY, Ong SWX, Lee TH, Lin RJH, Lim C, Teo J, Ren EC, Lye DC, Young BE, Ng LFP, Renia L. Rouers A, et al. Among authors: ngoh ezx. J Med Virol. 2023 Jan;95(1):e28258. doi: 10.1002/jmv.28258. Epub 2022 Nov 16. J Med Virol. 2023. PMID: 36305052 Free PMC article.
Waning of specific antibodies against Delta and Omicron variants five months after a third dose of BNT162b2 SARS-CoV-2 vaccine in elderly individuals.
Goh YS, Rouers A, Fong SW, Zhuo NZ, Hor PX, Loh CY, Huang Y, Neo VK, Kam IKJ, Wang B, Ngoh EZX, Salleh SNM, Lee RTC, Pada S, Sun LJ, Ong DLS, Somani J, Lee ES; NCID Study Group; COVID-19 Study Group; Maurer-Stroh S, Wang CI, Leo YS, Ren EC, Lye DC, Young BE, Ng LFP, Renia L. Goh YS, et al. Among authors: ngoh ezx. Front Immunol. 2022 Nov 14;13:1031852. doi: 10.3389/fimmu.2022.1031852. eCollection 2022. Front Immunol. 2022. PMID: 36451833 Free PMC article.
18 results