Mirza S - Search Results

1

2-Substituted thienotetrahydropyridine derivatives: Allosteric ectonucleotidase inhibitors.

Schäkel L, Mirza S, Pietsch M, Lee SY, Keuler T, Sylvester K, Pelletier J, Sévigny J, Pillaiyar T, Namasivayam V, Gütschow M, Müller CE. Schäkel L, et al. Among authors: mirza s. Arch Pharm (Weinheim). 2021 Dec;354(12):e2100300. doi: 10.1002/ardp.202100300. Epub 2021 Oct 26. Arch Pharm (Weinheim). 2021. PMID: 34697820

2

Development of a selective and highly sensitive fluorescence assay for nucleoside triphosphate diphosphohydrolase1 (NTPDase1, CD39).

Lee SY , Luo X , Namasivayam V , Geiss J , Mirza S , Pelletier J , Stephan H , Sévigny J , Müller CE . Lee SY , et al. Among authors: mirza s. Analyst. 2018 Nov 5;143(22):5417-5430. doi: 10.1039/c8an01108g. Analyst. 2018. PMID: 30303204

3

Identification of adenine-N9-(methoxy)ethyl-β-bisphosphonate as NPP1 inhibitor attenuates NPPase activity in human osteoarthritic chondrocytes.

Nassir M, Arad U, Lee SY, Journo S, Mirza S, Renn C, Zimmermann H, Pelletier J, Sévigny J, Müller CE, Fischer B. Nassir M, et al. Among authors: mirza s. Purinergic Signal. 2019 Jun;15(2):247-263. doi: 10.1007/s11302-019-09649-2. Epub 2019 Apr 25. Purinergic Signal. 2019. PMID: 31025169 Free PMC article.

4

Adenine-(methoxy)-ethoxy-P_α,α-dithio-triphosphate inhibits pathologic calcium pyrophosphate deposition in osteoarthritic human chondrocytes.

Nassir M, Mirza S, Arad U, Lee S, Rafehi M, Yaw Attah I, Renn C, Zimmermann H, Pelletier J, Sévigny J, Müller CE, Fischer B. Nassir M, et al. Among authors: mirza s. Org Biomol Chem. 2019 Nov 27;17(46):9913-9923. doi: 10.1039/c9ob02199j. Org Biomol Chem. 2019. PMID: 31720670

5

Nucleotide Analog ARL67156 as a Lead Structure for the Development of CD39 and Dual CD39/CD73 Ectonucleotidase Inhibitors.

Schäkel L, Schmies CC, Idris RM, Luo X, Lee SY, Lopez V, Mirza S, Vu TH, Pelletier J, Sévigny J, Namasivayam V, Müller CE. Schäkel L, et al. Among authors: mirza s. Front Pharmacol. 2020 Sep 8;11:1294. doi: 10.3389/fphar.2020.01294. eCollection 2020. Front Pharmacol. 2020. PMID: 33013365 Free PMC article.

6

Sulfated Polysaccharides from Macroalgae Are Potent Dual Inhibitors of Human ATP-Hydrolyzing Ectonucleotidases NPP1 and CD39.

Lopez V, Schäkel L, Schuh HJM, Schmidt MS, Mirza S, Renn C, Pelletier J, Lee SY, Sévigny J, Alban S, Bendas G, Müller CE. Lopez V, et al. Among authors: mirza s. Mar Drugs. 2021 Jan 22;19(2):51. doi: 10.3390/md19020051. Mar Drugs. 2021. PMID: 33499103 Free PMC article.

7

Targeting the Main Protease of SARS-CoV-2: From the Establishment of High Throughput Screening to the Design of Tailored Inhibitors.

Breidenbach J, Lemke C, Pillaiyar T, Schäkel L, Al Hamwi G, Diett M, Gedschold R, Geiger N, Lopez V, Mirza S, Namasivayam V, Schiedel AC, Sylvester K, Thimm D, Vielmuth C, Phuong Vu L, Zyulina M, Bodem J, Gütschow M, Müller CE. Breidenbach J, et al. Among authors: mirza s. Angew Chem Int Ed Engl. 2021 Apr 26;60(18):10423-10429. doi: 10.1002/anie.202016961. Epub 2021 Mar 24. Angew Chem Int Ed Engl. 2021. PMID: 33655614 Free PMC article.

8

Discovery of potent nucleotide pyrophosphatase/phosphodiesterase3 (NPP3) inhibitors with ancillary carbonic anhydrase inhibition for cancer (immuno)therapy.

Lee SY, Namasivayam V, Boshta NM, Perotti A, Mirza S, Bua S, Supuran CT, Müller CE. Lee SY, et al. Among authors: mirza s. RSC Med Chem. 2021 Jun 16;12(7):1187-1206. doi: 10.1039/d1md00117e. eCollection 2021 Jul 21. RSC Med Chem. 2021. PMID: 34355184 Free PMC article.

9

Protein kinase inhibitor ceritinib blocks ectonucleotidase CD39 - a promising target for cancer immunotherapy.

Schäkel L, Mirza S, Winzer R, Lopez V, Idris R, Al-Hroub H, Pelletier J, Sévigny J, Tolosa E, Müller CE. Schäkel L, et al. Among authors: mirza s. J Immunother Cancer. 2022 Aug;10(8):e004660. doi: 10.1136/jitc-2022-004660. J Immunother Cancer. 2022. PMID: 35981785 Free PMC article.

10

Synthesis and structure-activity relationships of ticlopidine derivatives and analogs as inhibitors of ectonucleotidase CD39.

Bi C, Schäkel L, Mirza S, Sylvester K, Pelletier J, Lee SY, Pillaiyar T, Sévigny J, Müller CE. Bi C, et al. Among authors: mirza s. Bioorg Chem. 2023 Jun;135:106460. doi: 10.1016/j.bioorg.2023.106460. Epub 2023 Mar 11. Bioorg Chem. 2023. PMID: 37023582

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