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Y box binding protein 1 inhibition as a targeted therapy for ovarian cancer.
Tailor D, Resendez A, Garcia-Marques FJ, Pandrala M, Going CC, Bermudez A, Kumar V, Rafat M, Nambiar DK, Honkala A, Le QT, Sledge GW, Graves E, Pitteri SJ, Malhotra SV. Tailor D, et al. Among authors: malhotra sv. Cell Chem Biol. 2021 Aug 19;28(8):1206-1220.e6. doi: 10.1016/j.chembiol.2021.02.014. Epub 2021 Mar 12. Cell Chem Biol. 2021. PMID: 33713600 Free article.
Novel Aza-podophyllotoxin derivative induces oxidative phosphorylation and cell death via AMPK activation in triple-negative breast cancer.
Tailor D, Going CC, Resendez A, Kumar V, Nambiar DK, Li Y, Dheeraj A, LaGory EL, Ghoochani A, Birk AM, Stoyanova T, Ye J, Giaccia AJ, Le QT, Singh RP, Sledge GW, Pitteri SJ, Malhotra SV. Tailor D, et al. Among authors: malhotra sv. Br J Cancer. 2021 Feb;124(3):604-615. doi: 10.1038/s41416-020-01137-4. Epub 2020 Nov 3. Br J Cancer. 2021. PMID: 33139797 Free PMC article.
Reengineering Ponatinib to Minimize Cardiovascular Toxicity.
Hnatiuk AP, Bruyneel AAN, Tailor D, Pandrala M, Dheeraj A, Li W, Serrano R, Feyen DAM, Vu MM, Amatya P, Gupta S, Nakauchi Y, Morgado I, Wiebking V, Liao R, Porteus MH, Majeti R, Malhotra SV, Mercola M. Hnatiuk AP, et al. Among authors: malhotra sv. Cancer Res. 2022 Aug 3;82(15):2777-2791. doi: 10.1158/0008-5472.CAN-21-3652. Cancer Res. 2022. PMID: 35763671 Free PMC article.
Highlights from Stanford Drug Discovery Symposium 2021.
Chase AJ, Malhotra SV, Mercola M, Singh K, Wu JC. Chase AJ, et al. Among authors: malhotra sv. Cardiovasc Res. 2021 Aug 29;117(10):e132-e134. doi: 10.1093/cvr/cvab250. Cardiovasc Res. 2021. PMID: 34417601 Free PMC article. No abstract available.
SU086, an inhibitor of HSP90, impairs glycolysis and represents a treatment strategy for advanced prostate cancer.
Rice MA, Kumar V, Tailor D, Garcia-Marques FJ, Hsu EC, Liu S, Bermudez A, Kanchustambham V, Shankar V, Inde Z, Alabi BR, Muruganantham A, Shen M, Pandrala M, Nolley R, Aslan M, Ghoochani A, Agarwal A, Buckup M, Kumar M, Going CC, Peehl DM, Dixon SJ, Zare RN, Brooks JD, Pitteri SJ, Malhotra SV, Stoyanova T. Rice MA, et al. Among authors: malhotra sv. Cell Rep Med. 2022 Feb 2;3(2):100502. doi: 10.1016/j.xcrm.2021.100502. eCollection 2022 Feb 15. Cell Rep Med. 2022. PMID: 35243415 Free PMC article.
Targeting the Hsp40/Hsp70 Chaperone Axis as a Novel Strategy to Treat Castration-Resistant Prostate Cancer.
Moses MA, Kim YS, Rivera-Marquez GM, Oshima N, Watson MJ, Beebe KE, Wells C, Lee S, Zuehlke AD, Shao H, Bingman WE 3rd, Kumar V, Malhotra SV, Weigel NL, Gestwicki JE, Trepel JB, Neckers LM. Moses MA, et al. Among authors: malhotra sv. Cancer Res. 2018 Jul 15;78(14):4022-4035. doi: 10.1158/0008-5472.CAN-17-3728. Epub 2018 May 15. Cancer Res. 2018. PMID: 29764864 Free PMC article.
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