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Hsp70-containing extracellular vesicles are capable of activating of adaptive immunity in models of mouse melanoma and colon carcinoma.
Komarova EY, Suezov RV, Nikotina AD, Aksenov ND, Garaeva LA, Shtam TA, Zhakhov AV, Martynova MG, Bystrova OA, Istomina MS, Ischenko AM, Margulis BA, Guzhova IV. Komarova EY, et al. Among authors: nikotina ad. Sci Rep. 2021 Oct 29;11(1):21314. doi: 10.1038/s41598-021-00734-4. Sci Rep. 2021. PMID: 34716378 Free PMC article.
Small molecules preventing GAPDH aggregation are therapeutically applicable in cell and rat models of oxidative stress.
Lazarev VF, Nikotina AD, Semenyuk PI, Evstafyeva DB, Mikhaylova ER, Muronetz VI, Shevtsov MA, Tolkacheva AV, Dobrodumov AV, Shavarda AL, Guzhova IV, Margulis BA. Lazarev VF, et al. Among authors: nikotina ad. Free Radic Biol Med. 2016 Mar;92:29-38. doi: 10.1016/j.freeradbiomed.2015.12.025. Epub 2015 Dec 31. Free Radic Biol Med. 2016. PMID: 26748070
Properties of substances inhibiting aggregation of oxidized GAPDH: Data on the interaction with the enzyme and the impact on its intracellular content.
Lazarev VF, Nikotina AD, Semenyuk PI, Evstafyeva DB, Mikhaylova ER, Muronetz VI, Shevtsov MA, Tolkacheva AV, Dobrodumov AV, Shavarda AL, Guzhova IV, Margulis BA. Lazarev VF, et al. Among authors: nikotina ad. Data Brief. 2016 Feb 27;7:524-8. doi: 10.1016/j.dib.2016.02.054. eCollection 2016 Jun. Data Brief. 2016. PMID: 27054152 Free PMC article.
Prevention of High Glucose-Mediated EMT by Inhibition of Hsp70 Chaperone.
Nikotina AD, Vladimirova SA, Komarova EY, Alexeev D, Efremov S, Leonova E, Pavlov R, Kartsev VG, Polonik SG, Margulis BA, Guzhova IV. Nikotina AD, et al. Int J Mol Sci. 2021 Jun 27;22(13):6902. doi: 10.3390/ijms22136902. Int J Mol Sci. 2021. PMID: 34199046 Free PMC article.
15 results