de Veer SJ - Search Results

1

An Ultrapotent and Selective Cyclic Peptide Inhibitor of Human β-Factor XIIa in a Cyclotide Scaffold.

Liu W, de Veer SJ, Huang YH, Sengoku T, Okada C, Ogata K, Zdenek CN, Fry BG, Swedberg JE, Passioura T, Craik DJ, Suga H. Liu W, et al. Among authors: de veer sj. J Am Chem Soc. 2021 Nov 10;143(44):18481-18489. doi: 10.1021/jacs.1c07574. Epub 2021 Nov 1. J Am Chem Soc. 2021. PMID: 34723512

2

Substrate-guided design of a potent and selective kallikrein-related peptidase inhibitor for kallikrein 4.

Swedberg JE, Nigon LV, Reid JC, de Veer SJ, Walpole CM, Stephens CR, Walsh TP, Takayama TK, Hooper JD, Clements JA, Buckle AM, Harris JM. Swedberg JE, et al. Among authors: de veer sj. Chem Biol. 2009 Jun 26;16(6):633-43. doi: 10.1016/j.chembiol.2009.05.008. Chem Biol. 2009. PMID: 19549601

3

Natural and engineered kallikrein inhibitors: an emerging pharmacopoeia.

Swedberg JE, de Veer SJ, Harris JM. Swedberg JE, et al. Among authors: de veer sj. Biol Chem. 2010 Apr;391(4):357-74. doi: 10.1515/BC.2010.037. Biol Chem. 2010. PMID: 20180638 Free article. Review.

4

Mastering the canonical loop of serine protease inhibitors: enhancing potency by optimising the internal hydrogen bond network.

Swedberg JE, de Veer SJ, Sit KC, Reboul CF, Buckle AM, Harris JM. Swedberg JE, et al. Among authors: de veer sj. PLoS One. 2011 Apr 27;6(4):e19302. doi: 10.1371/journal.pone.0019302. PLoS One. 2011. PMID: 21556330 Free PMC article.

5

Non-combinatorial library screening reveals subsite cooperativity and identifies new high-efficiency substrates for kallikrein-related peptidase 14.

de Veer SJ, Swedberg JE, Parker EA, Harris JM. de Veer SJ, et al. Biol Chem. 2012 Apr;393(5):331-41. doi: 10.1515/bc-2011-250. Biol Chem. 2012. PMID: 22505516 Free article.

6

Selective cleavage of human sex hormone-binding globulin by kallikrein-related peptidases and effects on androgen action in LNCaP prostate cancer cells.

Sanchez WY, de Veer SJ, Swedberg JE, Hong EJ, Reid JC, Walsh TP, Hooper JD, Hammond GL, Clements JA, Harris JM. Sanchez WY, et al. Among authors: de veer sj. Endocrinology. 2012 Jul;153(7):3179-89. doi: 10.1210/en.2012-1011. Epub 2012 Apr 30. Endocrinology. 2012. PMID: 22547569 Free article.

7

Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1.

de Veer SJ, Ukolova SS, Munro CA, Swedberg JE, Buckle AM, Harris JM. de Veer SJ, et al. Biopolymers. 2013 Mar 11. doi: 10.1002/peps.22231. Online ahead of print. Biopolymers. 2013. PMID: 23494567

8

Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1.

de Veer SJ, Ukolova SS, Munro CA, Swedberg JE, Buckle AM, Harris JM. de Veer SJ, et al. Biopolymers. 2013 Sep;100(5):510-8. doi: 10.1002/bip.22231. Biopolymers. 2013. PMID: 24078181

9

Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition.

de Veer SJ, Swedberg JE, Akcan M, Rosengren KJ, Brattsand M, Craik DJ, Harris JM. de Veer SJ, et al. Biochem J. 2015 Jul 15;469(2):243-53. doi: 10.1042/BJ20150412. Epub 2015 May 18. Biochem J. 2015. PMID: 25981970

10

Improving the Selectivity of Engineered Protease Inhibitors: Optimizing the P2 Prime Residue Using a Versatile Cyclic Peptide Library.

de Veer SJ, Wang CK, Harris JM, Craik DJ, Swedberg JE. de Veer SJ, et al. J Med Chem. 2015 Oct 22;58(20):8257-68. doi: 10.1021/acs.jmedchem.5b01148. Epub 2015 Oct 5. J Med Chem. 2015. PMID: 26393374

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