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Gain-of-function cardiomyopathic mutations in RBM20 rewire splicing regulation and re-distribute ribonucleoprotein granules within processing bodies.
Fenix AM, Miyaoka Y, Bertero A, Blue SM, Spindler MJ, Tan KKB, Perez-Bermejo JA, Chan AH, Mayerl SJ, Nguyen TD, Russell CR, Lizarraga PP, Truong A, So PL, Kulkarni A, Chetal K, Sathe S, Sniadecki NJ, Yeo GW, Murry CE, Conklin BR, Salomonis N. Fenix AM, et al. Among authors: sniadecki nj. Nat Commun. 2021 Nov 3;12(1):6324. doi: 10.1038/s41467-021-26623-y. Nat Commun. 2021. PMID: 34732726 Free PMC article.
Correcting dilated cardiomyopathy with fibroblast-targeted p38 deficiency.
Bretherton RC, Reichardt IM, Zabrecky KA, Goldstein AJ, Bailey LRJ, Bugg D, McMillen TS, Kooiker KB, Flint GV, Martinson A, Gunaje J, Koser F, Plaster E, Linke WA, Regnier M, Moussavi-Harami F, Sniadecki NJ, DeForest CA, Davis J. Bretherton RC, et al. Among authors: sniadecki nj. bioRxiv [Preprint]. 2023 Jan 23:2023.01.23.523684. doi: 10.1101/2023.01.23.523684. bioRxiv. 2023. PMID: 36747691 Free PMC article. Preprint.
YAP dysregulation triggers hypertrophy by CCN2 secretion and TGFβ uptake in human pluripotent stem cell-derived cardiomyocytes.
Chirikian O, Faynus MA, Merk M, Singh Z, Muray C, Pham J, Chialastri A, Vander Roest A, Goldstein A, Pyle T, Lane KV, Roberts B, Smith JE, Gunawardane RN, Sniadecki NJ, Mack DL, Davis J, Bernstein D, Streichan SJ, Clegg DO, Dey SS, Wilson MZ, Pruitt BL. Chirikian O, et al. Among authors: sniadecki nj. bioRxiv [Preprint]. 2024 Jun 5:2024.06.03.597045. doi: 10.1101/2024.06.03.597045. bioRxiv. 2024. PMID: 38895282 Free PMC article. Preprint.
Let-7 family of microRNA is required for maturation and adult-like metabolism in stem cell-derived cardiomyocytes.
Kuppusamy KT, Jones DC, Sperber H, Madan A, Fischer KA, Rodriguez ML, Pabon L, Zhu WZ, Tulloch NL, Yang X, Sniadecki NJ, Laflamme MA, Ruzzo WL, Murry CE, Ruohola-Baker H. Kuppusamy KT, et al. Among authors: sniadecki nj. Proc Natl Acad Sci U S A. 2015 May 26;112(21):E2785-94. doi: 10.1073/pnas.1424042112. Epub 2015 May 11. Proc Natl Acad Sci U S A. 2015. PMID: 25964336 Free PMC article.
Chromatin compartment dynamics in a haploinsufficient model of cardiac laminopathy.
Bertero A, Fields PA, Smith AST, Leonard A, Beussman K, Sniadecki NJ, Kim DH, Tse HF, Pabon L, Shendure J, Noble WS, Murry CE. Bertero A, et al. Among authors: sniadecki nj. J Cell Biol. 2019 Sep 2;218(9):2919-2944. doi: 10.1083/jcb.201902117. Epub 2019 Aug 8. J Cell Biol. 2019. PMID: 31395619 Free PMC article.
Fatty Acids Enhance the Maturation of Cardiomyocytes Derived from Human Pluripotent Stem Cells.
Yang X, Rodriguez ML, Leonard A, Sun L, Fischer KA, Wang Y, Ritterhoff J, Zhao L, Kolwicz SC Jr, Pabon L, Reinecke H, Sniadecki NJ, Tian R, Ruohola-Baker H, Xu H, Murry CE. Yang X, et al. Among authors: sniadecki nj. Stem Cell Reports. 2019 Oct 8;13(4):657-668. doi: 10.1016/j.stemcr.2019.08.013. Epub 2019 Sep 26. Stem Cell Reports. 2019. PMID: 31564645 Free PMC article.
77 results